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Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological S...
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| Zeitschriftentitel: | Journal of Clinical Microbiology |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Journal of Clinical Microbiology, 43, 2005, 9, S. 4815-4819 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Society for Microbiology
|
| Schlagwörter: |
| author_facet |
Bhattacharya, Dhruva Haque, Rashidul Singh, Upinder Bhattacharya, Dhruva Haque, Rashidul Singh, Upinder |
|---|---|
| author |
Bhattacharya, Dhruva Haque, Rashidul Singh, Upinder |
| spellingShingle |
Bhattacharya, Dhruva Haque, Rashidul Singh, Upinder Journal of Clinical Microbiology Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies Microbiology (medical) |
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bhattacharya, dhruva |
| spelling |
Bhattacharya, Dhruva Haque, Rashidul Singh, Upinder 0095-1137 1098-660X American Society for Microbiology Microbiology (medical) http://dx.doi.org/10.1128/jcm.43.9.4815-4819.2005 <jats:title>ABSTRACT</jats:title> <jats:p> To evaluate genetic variability among <jats:italic>Entamoeba histolytica</jats:italic> strains, we sequenced 9,077 bp from each of 14 isolates. The polymorphism rates from coding and noncoding regions were significantly different (0.07% and 0.37%, respectively), indicating that these regions are subject to different selection pressures. Additionally, single nucleotide polymorphisms (SNPs) potentially associated with specific clinical outcomes were identified. </jats:p> Coding and Noncoding Genomic Regions of <i>Entamoeba histolytica</i> Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies Journal of Clinical Microbiology |
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| title |
Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| title_unstemmed |
Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| title_full |
Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| title_fullStr |
Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| title_full_unstemmed |
Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| title_short |
Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| title_sort |
coding and noncoding genomic regions of
<i>entamoeba histolytica</i>
have significantly different rates of sequence polymorphisms: implications for epidemiological studies |
| topic |
Microbiology (medical) |
| url |
http://dx.doi.org/10.1128/jcm.43.9.4815-4819.2005 |
| publishDate |
2005 |
| physical |
4815-4819 |
| description |
<jats:title>ABSTRACT</jats:title>
<jats:p>
To evaluate genetic variability among
<jats:italic>Entamoeba histolytica</jats:italic>
strains, we sequenced 9,077 bp from each of 14 isolates. The polymorphism rates from coding and noncoding regions were significantly different (0.07% and 0.37%, respectively), indicating that these regions are subject to different selection pressures. Additionally, single nucleotide polymorphisms (SNPs) potentially associated with specific clinical outcomes were identified.
</jats:p> |
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| description | <jats:title>ABSTRACT</jats:title> <jats:p> To evaluate genetic variability among <jats:italic>Entamoeba histolytica</jats:italic> strains, we sequenced 9,077 bp from each of 14 isolates. The polymorphism rates from coding and noncoding regions were significantly different (0.07% and 0.37%, respectively), indicating that these regions are subject to different selection pressures. Additionally, single nucleotide polymorphisms (SNPs) potentially associated with specific clinical outcomes were identified. </jats:p> |
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| spelling | Bhattacharya, Dhruva Haque, Rashidul Singh, Upinder 0095-1137 1098-660X American Society for Microbiology Microbiology (medical) http://dx.doi.org/10.1128/jcm.43.9.4815-4819.2005 <jats:title>ABSTRACT</jats:title> <jats:p> To evaluate genetic variability among <jats:italic>Entamoeba histolytica</jats:italic> strains, we sequenced 9,077 bp from each of 14 isolates. The polymorphism rates from coding and noncoding regions were significantly different (0.07% and 0.37%, respectively), indicating that these regions are subject to different selection pressures. Additionally, single nucleotide polymorphisms (SNPs) potentially associated with specific clinical outcomes were identified. </jats:p> Coding and Noncoding Genomic Regions of <i>Entamoeba histolytica</i> Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies Journal of Clinical Microbiology |
| spellingShingle | Bhattacharya, Dhruva, Haque, Rashidul, Singh, Upinder, Journal of Clinical Microbiology, Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies, Microbiology (medical) |
| title | Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| title_full | Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| title_fullStr | Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| title_full_unstemmed | Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| title_short | Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| title_sort | coding and noncoding genomic regions of <i>entamoeba histolytica</i> have significantly different rates of sequence polymorphisms: implications for epidemiological studies |
| title_unstemmed | Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies |
| topic | Microbiology (medical) |
| url | http://dx.doi.org/10.1128/jcm.43.9.4815-4819.2005 |