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Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological S...
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| Zeitschriftentitel: | Journal of Clinical Microbiology |
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| Personen und Körperschaften: | , , |
| In: | Journal of Clinical Microbiology, 43, 2005, 9, S. 4815-4819 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Society for Microbiology
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| Schlagwörter: |
| Zusammenfassung: | <jats:title>ABSTRACT</jats:title> <jats:p> To evaluate genetic variability among <jats:italic>Entamoeba histolytica</jats:italic> strains, we sequenced 9,077 bp from each of 14 isolates. The polymorphism rates from coding and noncoding regions were significantly different (0.07% and 0.37%, respectively), indicating that these regions are subject to different selection pressures. Additionally, single nucleotide polymorphisms (SNPs) potentially associated with specific clinical outcomes were identified. </jats:p> |
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| Umfang: | 4815-4819 |
| ISSN: |
1098-660X
0095-1137 |
| DOI: | 10.1128/jcm.43.9.4815-4819.2005 |