Biosynthesis of Natural Flavanones in Saccharomyces cerevisiae

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Bibliographische Detailangaben
Zeitschriftentitel:	Applied and Environmental Microbiology
Personen und Körperschaften:	Yan, Yajun, Kohli, Abhijeet, Koffas, Mattheos A. G.
In:	Applied and Environmental Microbiology, 71, 2005, 9, S. 5610-5613
Format:	E-Article
Sprache:	Englisch
veröffentlicht:	American Society for Microbiology
Schlagwörter:	Ecology Applied Microbiology and Biotechnology Food Science Biotechnology

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Zusammenfassung:	<jats:title>ABSTRACT</jats:title> <jats:p> A four-step flavanone biosynthetic pathway was constructed and introduced into <jats:italic>Saccharomyces cerevisiae</jats:italic> . The recombinant yeast strain was fed with phenylpropanoid acids and produced the flavanones naringenin and pinocembrin 62 and 22 times more efficiently compared to previously reported recombinant prokaryotic strains. Microbial biosynthesis of the flavanone eriodictyol was also achieved. </jats:p>
Umfang:	5610-5613
ISSN:	0099-2240 1098-5336
DOI:	10.1128/aem.71.9.5610-5613.2005