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Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study
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| Zeitschriftentitel: | Alimentary Pharmacology & Therapeutics |
|---|---|
| Personen und Körperschaften: | , , , , , , |
| In: | Alimentary Pharmacology & Therapeutics, 21, 2005, 4, S. 485-489 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
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| Schlagwörter: |
| author_facet |
Trevisani, L. Sartori, S. Rossi, M. R. Ruina, M. Matarese, V. Gullini, S. Abbasciano, V. Trevisani, L. Sartori, S. Rossi, M. R. Ruina, M. Matarese, V. Gullini, S. Abbasciano, V. |
|---|---|
| author |
Trevisani, L. Sartori, S. Rossi, M. R. Ruina, M. Matarese, V. Gullini, S. Abbasciano, V. |
| spellingShingle |
Trevisani, L. Sartori, S. Rossi, M. R. Ruina, M. Matarese, V. Gullini, S. Abbasciano, V. Alimentary Pharmacology & Therapeutics Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study Pharmacology (medical) Gastroenterology Hepatology |
| author_sort |
trevisani, l. |
| spelling |
Trevisani, L. Sartori, S. Rossi, M. R. Ruina, M. Matarese, V. Gullini, S. Abbasciano, V. 0269-2813 1365-2036 Wiley Pharmacology (medical) Gastroenterology Hepatology http://dx.doi.org/10.1111/j.1365-2036.2005.02355.x <jats:title>Summary</jats:title><jats:p><jats:bold>Background</jats:bold> : Detection of <jats:italic>Helicobacter pylori</jats:italic> antigen in faeces is a valid method to diagnose <jats:italic>H. pylori</jats:italic> infection. Presently available stool tests are performed in the laboratory, and diagnostic report is delayed.</jats:p><jats:p><jats:bold>Aim</jats:bold> : To evaluate a new rapid stool test in a pre‐treatment setting and to compare it with a validated laboratory stool test.</jats:p><jats:p><jats:bold>Methods</jats:bold> : A total of 105 patients underwent gastroscopy with brush cytology, and biopsies for histology and rapid urease test, to assess <jats:italic>H. pylori</jats:italic> presence. <jats:italic>Helicobacter pylori</jats:italic>‐status was considered positive if at least two tests were positive; negative if all tests were negative; indeterminate if one test was positive and two negative. Stool specimens were tested using either a rapid immunoassay kit (ImmunoCard STAT) or a laboratory enzyme immunoassay kit (Hp StAR).</jats:p><jats:p><jats:bold>Results</jats:bold> : Sixty patients were infected with <jats:italic>H. pylori</jats:italic>, 44 non‐infected, one indeterminate. The sensitivity and specificity of ImmunoCard STAT were 85 and 93%; those of Hp StAR were 88 and 100% (not significant).</jats:p><jats:p><jats:bold>Conclusions</jats:bold> : ImmunoCard STAT seems a reliable method for detecting <jats:italic>H. pylori</jats:italic> in untreated patients. It could replace laboratory stool tests, as it is easy and can be performed quickly. These characteristics might be a breakthrough for diagnosing <jats:italic>H. pylori</jats:italic> in the doctor's office.</jats:p> Evaluation of a new rapid immunoassay for the detection of <i>Helicobacter pylori</i> in faeces: a prospective pilot study Alimentary Pharmacology & Therapeutics |
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| title |
Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| title_unstemmed |
Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| title_full |
Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| title_fullStr |
Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| title_full_unstemmed |
Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| title_short |
Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| title_sort |
evaluation of a new rapid immunoassay for the detection of <i>helicobacter pylori</i> in faeces: a prospective pilot study |
| topic |
Pharmacology (medical) Gastroenterology Hepatology |
| url |
http://dx.doi.org/10.1111/j.1365-2036.2005.02355.x |
| publishDate |
2005 |
| physical |
485-489 |
| description |
<jats:title>Summary</jats:title><jats:p><jats:bold>Background</jats:bold> : Detection of <jats:italic>Helicobacter pylori</jats:italic> antigen in faeces is a valid method to diagnose <jats:italic>H. pylori</jats:italic> infection. Presently available stool tests are performed in the laboratory, and diagnostic report is delayed.</jats:p><jats:p><jats:bold>Aim</jats:bold> : To evaluate a new rapid stool test in a pre‐treatment setting and to compare it with a validated laboratory stool test.</jats:p><jats:p><jats:bold>Methods</jats:bold> : A total of 105 patients underwent gastroscopy with brush cytology, and biopsies for histology and rapid urease test, to assess <jats:italic>H. pylori</jats:italic> presence. <jats:italic>Helicobacter pylori</jats:italic>‐status was considered positive if at least two tests were positive; negative if all tests were negative; indeterminate if one test was positive and two negative. Stool specimens were tested using either a rapid immunoassay kit (ImmunoCard STAT) or a laboratory enzyme immunoassay kit (Hp StAR).</jats:p><jats:p><jats:bold>Results</jats:bold> : Sixty patients were infected with <jats:italic>H. pylori</jats:italic>, 44 non‐infected, one indeterminate. The sensitivity and specificity of ImmunoCard STAT were 85 and 93%; those of Hp StAR were 88 and 100% (not significant).</jats:p><jats:p><jats:bold>Conclusions</jats:bold> : ImmunoCard STAT seems a reliable method for detecting <jats:italic>H. pylori</jats:italic> in untreated patients. It could replace laboratory stool tests, as it is easy and can be performed quickly. These characteristics might be a breakthrough for diagnosing <jats:italic>H. pylori</jats:italic> in the doctor's office.</jats:p> |
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| author | Trevisani, L., Sartori, S., Rossi, M. R., Ruina, M., Matarese, V., Gullini, S., Abbasciano, V. |
| author_facet | Trevisani, L., Sartori, S., Rossi, M. R., Ruina, M., Matarese, V., Gullini, S., Abbasciano, V., Trevisani, L., Sartori, S., Rossi, M. R., Ruina, M., Matarese, V., Gullini, S., Abbasciano, V. |
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| description | <jats:title>Summary</jats:title><jats:p><jats:bold>Background</jats:bold> : Detection of <jats:italic>Helicobacter pylori</jats:italic> antigen in faeces is a valid method to diagnose <jats:italic>H. pylori</jats:italic> infection. Presently available stool tests are performed in the laboratory, and diagnostic report is delayed.</jats:p><jats:p><jats:bold>Aim</jats:bold> : To evaluate a new rapid stool test in a pre‐treatment setting and to compare it with a validated laboratory stool test.</jats:p><jats:p><jats:bold>Methods</jats:bold> : A total of 105 patients underwent gastroscopy with brush cytology, and biopsies for histology and rapid urease test, to assess <jats:italic>H. pylori</jats:italic> presence. <jats:italic>Helicobacter pylori</jats:italic>‐status was considered positive if at least two tests were positive; negative if all tests were negative; indeterminate if one test was positive and two negative. Stool specimens were tested using either a rapid immunoassay kit (ImmunoCard STAT) or a laboratory enzyme immunoassay kit (Hp StAR).</jats:p><jats:p><jats:bold>Results</jats:bold> : Sixty patients were infected with <jats:italic>H. pylori</jats:italic>, 44 non‐infected, one indeterminate. The sensitivity and specificity of ImmunoCard STAT were 85 and 93%; those of Hp StAR were 88 and 100% (not significant).</jats:p><jats:p><jats:bold>Conclusions</jats:bold> : ImmunoCard STAT seems a reliable method for detecting <jats:italic>H. pylori</jats:italic> in untreated patients. It could replace laboratory stool tests, as it is easy and can be performed quickly. These characteristics might be a breakthrough for diagnosing <jats:italic>H. pylori</jats:italic> in the doctor's office.</jats:p> |
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| institution | DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275 |
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| spelling | Trevisani, L. Sartori, S. Rossi, M. R. Ruina, M. Matarese, V. Gullini, S. Abbasciano, V. 0269-2813 1365-2036 Wiley Pharmacology (medical) Gastroenterology Hepatology http://dx.doi.org/10.1111/j.1365-2036.2005.02355.x <jats:title>Summary</jats:title><jats:p><jats:bold>Background</jats:bold> : Detection of <jats:italic>Helicobacter pylori</jats:italic> antigen in faeces is a valid method to diagnose <jats:italic>H. pylori</jats:italic> infection. Presently available stool tests are performed in the laboratory, and diagnostic report is delayed.</jats:p><jats:p><jats:bold>Aim</jats:bold> : To evaluate a new rapid stool test in a pre‐treatment setting and to compare it with a validated laboratory stool test.</jats:p><jats:p><jats:bold>Methods</jats:bold> : A total of 105 patients underwent gastroscopy with brush cytology, and biopsies for histology and rapid urease test, to assess <jats:italic>H. pylori</jats:italic> presence. <jats:italic>Helicobacter pylori</jats:italic>‐status was considered positive if at least two tests were positive; negative if all tests were negative; indeterminate if one test was positive and two negative. Stool specimens were tested using either a rapid immunoassay kit (ImmunoCard STAT) or a laboratory enzyme immunoassay kit (Hp StAR).</jats:p><jats:p><jats:bold>Results</jats:bold> : Sixty patients were infected with <jats:italic>H. pylori</jats:italic>, 44 non‐infected, one indeterminate. The sensitivity and specificity of ImmunoCard STAT were 85 and 93%; those of Hp StAR were 88 and 100% (not significant).</jats:p><jats:p><jats:bold>Conclusions</jats:bold> : ImmunoCard STAT seems a reliable method for detecting <jats:italic>H. pylori</jats:italic> in untreated patients. It could replace laboratory stool tests, as it is easy and can be performed quickly. These characteristics might be a breakthrough for diagnosing <jats:italic>H. pylori</jats:italic> in the doctor's office.</jats:p> Evaluation of a new rapid immunoassay for the detection of <i>Helicobacter pylori</i> in faeces: a prospective pilot study Alimentary Pharmacology & Therapeutics |
| spellingShingle | Trevisani, L., Sartori, S., Rossi, M. R., Ruina, M., Matarese, V., Gullini, S., Abbasciano, V., Alimentary Pharmacology & Therapeutics, Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study, Pharmacology (medical), Gastroenterology, Hepatology |
| title | Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| title_full | Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| title_fullStr | Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| title_full_unstemmed | Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| title_short | Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| title_sort | evaluation of a new rapid immunoassay for the detection of <i>helicobacter pylori</i> in faeces: a prospective pilot study |
| title_unstemmed | Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study |
| topic | Pharmacology (medical), Gastroenterology, Hepatology |
| url | http://dx.doi.org/10.1111/j.1365-2036.2005.02355.x |