Eintrag weiter verarbeiten
New generation analysis of thrombin generation in retinal vein thrombosis
Gespeichert in:
| Zeitschriftentitel: | Acta Ophthalmologica |
|---|---|
| Personen und Körperschaften: | , , , , |
| In: | Acta Ophthalmologica, 93, 2015, S255 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Fruschelli, M. Capozzoli, M. Scapellato, C. Calzoni, P. Puccetti, L. Fruschelli, M. Capozzoli, M. Scapellato, C. Calzoni, P. Puccetti, L. |
|---|---|
| author |
Fruschelli, M. Capozzoli, M. Scapellato, C. Calzoni, P. Puccetti, L. |
| spellingShingle |
Fruschelli, M. Capozzoli, M. Scapellato, C. Calzoni, P. Puccetti, L. Acta Ophthalmologica New generation analysis of thrombin generation in retinal vein thrombosis Ophthalmology General Medicine |
| author_sort |
fruschelli, m. |
| spelling |
Fruschelli, M. Capozzoli, M. Scapellato, C. Calzoni, P. Puccetti, L. 1755-375X 1755-3768 Wiley Ophthalmology General Medicine http://dx.doi.org/10.1111/j.1755-3768.2015.1496 <jats:sec><jats:title>Purpose</jats:title><jats:p>To investigate potential mechanisms involved in retinal vein occlusion (<jats:styled-content style="fixed-case">RVO</jats:styled-content>) we evaluated thrombin generation and soluble <jats:styled-content style="fixed-case">CD</jats:styled-content>40 ligand (<jats:styled-content style="fixed-case">sCD</jats:styled-content>40L) with respect to other known thrombophilic factors.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>68 patients affected by <jats:styled-content style="fixed-case">RVO</jats:styled-content> (28 central, 40 branch) and 60 healthy controls were evaluated for endogenous thrombin potential (<jats:styled-content style="fixed-case">ETP</jats:styled-content>) by a chromogenic method and <jats:styled-content style="fixed-case">sCD</jats:styled-content>40L by <jats:styled-content style="fixed-case">ELISA</jats:styled-content> technique. Polymerase chain reaction (<jats:styled-content style="fixed-case">PCR</jats:styled-content>) was employed for genetic polymorphisms and coagulative/chromogenic methods for othe coagulation factors.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Independently of genetic polymorphisms <jats:styled-content style="fixed-case">ETP</jats:styled-content> was increased in patients with <jats:styled-content style="fixed-case">CRVO</jats:styled-content> whereas <jats:styled-content style="fixed-case">sCD</jats:styled-content>40L was higher in the whole cohort.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Our data indicate an involvement of global coagulative activation in <jats:styled-content style="fixed-case">CRVO</jats:styled-content> patients as suggested by <jats:styled-content style="fixed-case">ETP</jats:styled-content>.</jats:p></jats:sec> New generation analysis of thrombin generation in retinal vein thrombosis Acta Ophthalmologica |
| doi_str_mv |
10.1111/j.1755-3768.2015.1496 |
| facet_avail |
Online Free |
| finc_class_facet |
Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9qLjE3NTUtMzc2OC4yMDE1LjE0OTY |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9qLjE3NTUtMzc2OC4yMDE1LjE0OTY |
| institution |
DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 |
| imprint |
Wiley, 2015 |
| imprint_str_mv |
Wiley, 2015 |
| issn |
1755-375X 1755-3768 |
| issn_str_mv |
1755-375X 1755-3768 |
| language |
English |
| mega_collection |
Wiley (CrossRef) |
| match_str |
fruschelli2015newgenerationanalysisofthrombingenerationinretinalveinthrombosis |
| publishDateSort |
2015 |
| publisher |
Wiley |
| recordtype |
ai |
| record_format |
ai |
| series |
Acta Ophthalmologica |
| source_id |
49 |
| title |
New generation analysis of thrombin generation in retinal vein thrombosis |
| title_unstemmed |
New generation analysis of thrombin generation in retinal vein thrombosis |
| title_full |
New generation analysis of thrombin generation in retinal vein thrombosis |
| title_fullStr |
New generation analysis of thrombin generation in retinal vein thrombosis |
| title_full_unstemmed |
New generation analysis of thrombin generation in retinal vein thrombosis |
| title_short |
New generation analysis of thrombin generation in retinal vein thrombosis |
| title_sort |
new generation analysis of thrombin generation in retinal vein thrombosis |
| topic |
Ophthalmology General Medicine |
| url |
http://dx.doi.org/10.1111/j.1755-3768.2015.1496 |
| publishDate |
2015 |
| physical |
|
| description |
<jats:sec><jats:title>Purpose</jats:title><jats:p>To investigate potential mechanisms involved in retinal vein occlusion (<jats:styled-content style="fixed-case">RVO</jats:styled-content>) we evaluated thrombin generation and soluble <jats:styled-content style="fixed-case">CD</jats:styled-content>40 ligand (<jats:styled-content style="fixed-case">sCD</jats:styled-content>40L) with respect to other known thrombophilic factors.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>68 patients affected by <jats:styled-content style="fixed-case">RVO</jats:styled-content> (28 central, 40 branch) and 60 healthy controls were evaluated for endogenous thrombin potential (<jats:styled-content style="fixed-case">ETP</jats:styled-content>) by a chromogenic method and <jats:styled-content style="fixed-case">sCD</jats:styled-content>40L by <jats:styled-content style="fixed-case">ELISA</jats:styled-content> technique. Polymerase chain reaction (<jats:styled-content style="fixed-case">PCR</jats:styled-content>) was employed for genetic polymorphisms and coagulative/chromogenic methods for othe coagulation factors.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Independently of genetic polymorphisms <jats:styled-content style="fixed-case">ETP</jats:styled-content> was increased in patients with <jats:styled-content style="fixed-case">CRVO</jats:styled-content> whereas <jats:styled-content style="fixed-case">sCD</jats:styled-content>40L was higher in the whole cohort.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Our data indicate an involvement of global coagulative activation in <jats:styled-content style="fixed-case">CRVO</jats:styled-content> patients as suggested by <jats:styled-content style="fixed-case">ETP</jats:styled-content>.</jats:p></jats:sec> |
| container_issue |
S255 |
| container_start_page |
0 |
| container_title |
Acta Ophthalmologica |
| container_volume |
93 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792333343694520324 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T14:10:47.869Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=New+generation+analysis+of+thrombin+generation+in+retinal+vein+thrombosis&rft.date=2015-10-01&genre=article&issn=1755-3768&volume=93&issue=S255&jtitle=Acta+Ophthalmologica&atitle=New+generation+analysis+of+thrombin+generation+in+retinal+vein+thrombosis&aulast=Puccetti&aufirst=L.&rft_id=info%3Adoi%2F10.1111%2Fj.1755-3768.2015.1496&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792333343694520324 |
| author | Fruschelli, M., Capozzoli, M., Scapellato, C., Calzoni, P., Puccetti, L. |
| author_facet | Fruschelli, M., Capozzoli, M., Scapellato, C., Calzoni, P., Puccetti, L., Fruschelli, M., Capozzoli, M., Scapellato, C., Calzoni, P., Puccetti, L. |
| author_sort | fruschelli, m. |
| container_issue | S255 |
| container_start_page | 0 |
| container_title | Acta Ophthalmologica |
| container_volume | 93 |
| description | <jats:sec><jats:title>Purpose</jats:title><jats:p>To investigate potential mechanisms involved in retinal vein occlusion (<jats:styled-content style="fixed-case">RVO</jats:styled-content>) we evaluated thrombin generation and soluble <jats:styled-content style="fixed-case">CD</jats:styled-content>40 ligand (<jats:styled-content style="fixed-case">sCD</jats:styled-content>40L) with respect to other known thrombophilic factors.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>68 patients affected by <jats:styled-content style="fixed-case">RVO</jats:styled-content> (28 central, 40 branch) and 60 healthy controls were evaluated for endogenous thrombin potential (<jats:styled-content style="fixed-case">ETP</jats:styled-content>) by a chromogenic method and <jats:styled-content style="fixed-case">sCD</jats:styled-content>40L by <jats:styled-content style="fixed-case">ELISA</jats:styled-content> technique. Polymerase chain reaction (<jats:styled-content style="fixed-case">PCR</jats:styled-content>) was employed for genetic polymorphisms and coagulative/chromogenic methods for othe coagulation factors.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Independently of genetic polymorphisms <jats:styled-content style="fixed-case">ETP</jats:styled-content> was increased in patients with <jats:styled-content style="fixed-case">CRVO</jats:styled-content> whereas <jats:styled-content style="fixed-case">sCD</jats:styled-content>40L was higher in the whole cohort.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Our data indicate an involvement of global coagulative activation in <jats:styled-content style="fixed-case">CRVO</jats:styled-content> patients as suggested by <jats:styled-content style="fixed-case">ETP</jats:styled-content>.</jats:p></jats:sec> |
| doi_str_mv | 10.1111/j.1755-3768.2015.1496 |
| facet_avail | Online, Free |
| finc_class_facet | Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9qLjE3NTUtMzc2OC4yMDE1LjE0OTY |
| imprint | Wiley, 2015 |
| imprint_str_mv | Wiley, 2015 |
| institution | DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14 |
| issn | 1755-375X, 1755-3768 |
| issn_str_mv | 1755-375X, 1755-3768 |
| language | English |
| last_indexed | 2024-03-01T14:10:47.869Z |
| match_str | fruschelli2015newgenerationanalysisofthrombingenerationinretinalveinthrombosis |
| mega_collection | Wiley (CrossRef) |
| physical | |
| publishDate | 2015 |
| publishDateSort | 2015 |
| publisher | Wiley |
| record_format | ai |
| recordtype | ai |
| series | Acta Ophthalmologica |
| source_id | 49 |
| spelling | Fruschelli, M. Capozzoli, M. Scapellato, C. Calzoni, P. Puccetti, L. 1755-375X 1755-3768 Wiley Ophthalmology General Medicine http://dx.doi.org/10.1111/j.1755-3768.2015.1496 <jats:sec><jats:title>Purpose</jats:title><jats:p>To investigate potential mechanisms involved in retinal vein occlusion (<jats:styled-content style="fixed-case">RVO</jats:styled-content>) we evaluated thrombin generation and soluble <jats:styled-content style="fixed-case">CD</jats:styled-content>40 ligand (<jats:styled-content style="fixed-case">sCD</jats:styled-content>40L) with respect to other known thrombophilic factors.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>68 patients affected by <jats:styled-content style="fixed-case">RVO</jats:styled-content> (28 central, 40 branch) and 60 healthy controls were evaluated for endogenous thrombin potential (<jats:styled-content style="fixed-case">ETP</jats:styled-content>) by a chromogenic method and <jats:styled-content style="fixed-case">sCD</jats:styled-content>40L by <jats:styled-content style="fixed-case">ELISA</jats:styled-content> technique. Polymerase chain reaction (<jats:styled-content style="fixed-case">PCR</jats:styled-content>) was employed for genetic polymorphisms and coagulative/chromogenic methods for othe coagulation factors.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Independently of genetic polymorphisms <jats:styled-content style="fixed-case">ETP</jats:styled-content> was increased in patients with <jats:styled-content style="fixed-case">CRVO</jats:styled-content> whereas <jats:styled-content style="fixed-case">sCD</jats:styled-content>40L was higher in the whole cohort.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Our data indicate an involvement of global coagulative activation in <jats:styled-content style="fixed-case">CRVO</jats:styled-content> patients as suggested by <jats:styled-content style="fixed-case">ETP</jats:styled-content>.</jats:p></jats:sec> New generation analysis of thrombin generation in retinal vein thrombosis Acta Ophthalmologica |
| spellingShingle | Fruschelli, M., Capozzoli, M., Scapellato, C., Calzoni, P., Puccetti, L., Acta Ophthalmologica, New generation analysis of thrombin generation in retinal vein thrombosis, Ophthalmology, General Medicine |
| title | New generation analysis of thrombin generation in retinal vein thrombosis |
| title_full | New generation analysis of thrombin generation in retinal vein thrombosis |
| title_fullStr | New generation analysis of thrombin generation in retinal vein thrombosis |
| title_full_unstemmed | New generation analysis of thrombin generation in retinal vein thrombosis |
| title_short | New generation analysis of thrombin generation in retinal vein thrombosis |
| title_sort | new generation analysis of thrombin generation in retinal vein thrombosis |
| title_unstemmed | New generation analysis of thrombin generation in retinal vein thrombosis |
| topic | Ophthalmology, General Medicine |
| url | http://dx.doi.org/10.1111/j.1755-3768.2015.1496 |