A 2D graphical representation of the sequences of DNA based on triplets and its application

Gespeichert in:

Bibliographische Detailangaben
Zeitschriftentitel:	EURASIP Journal on Bioinformatics and Systems Biology
Personen und Körperschaften:	Zou, Sai, Wang, Lei, Wang, Junfeng
In:	EURASIP Journal on Bioinformatics and Systems Biology, 2014, 2014, 1
Format:	E-Article
Sprache:	Englisch
veröffentlicht:	Springer Science and Business Media LLC
Schlagwörter:	Computational Mathematics Computer Science Applications General Biochemistry, Genetics and Molecular Biology

Details
Zusammenfassung:	<jats:title>Abstract</jats:title> <jats:p>In this paper, we first present a new concept of ‘weight’ for 64 triplets and define a different weight for each kind of triplet. Then, we give a novel 2D graphical representation for DNA sequences, which can transform a DNA sequence into a plot set to facilitate quantitative comparisons of DNA sequences. Thereafter, associating with a newly designed measure of similarity, we introduce a novel approach to make similarities/dissimilarities analysis of DNA sequences. Finally, the applications in similarities/dissimilarities analysis of the complete coding sequences of β-globin genes of 11 species illustrate the utilities of our newly proposed method.</jats:p>
ISSN:	1687-4153
DOI:	10.1186/1687-4153-2014-1