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Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL
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| Zeitschriftentitel: | Blood |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , , , , , |
| In: | Blood, 131, 2018, 16, S. 1809-1819 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Society of Hematology
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| Schlagwörter: |
| author_facet |
Vari, Frank Arpon, David Keane, Colm Hertzberg, Mark S. Talaulikar, Dipti Jain, Sanjiv Cui, Qingyan Han, Erica Tobin, Josh Bird, Robert Cross, Donna Hernandez, Annette Gould, Clare Birch, Simone Gandhi, Maher K. Vari, Frank Arpon, David Keane, Colm Hertzberg, Mark S. Talaulikar, Dipti Jain, Sanjiv Cui, Qingyan Han, Erica Tobin, Josh Bird, Robert Cross, Donna Hernandez, Annette Gould, Clare Birch, Simone Gandhi, Maher K. |
|---|---|
| author |
Vari, Frank Arpon, David Keane, Colm Hertzberg, Mark S. Talaulikar, Dipti Jain, Sanjiv Cui, Qingyan Han, Erica Tobin, Josh Bird, Robert Cross, Donna Hernandez, Annette Gould, Clare Birch, Simone Gandhi, Maher K. |
| spellingShingle |
Vari, Frank Arpon, David Keane, Colm Hertzberg, Mark S. Talaulikar, Dipti Jain, Sanjiv Cui, Qingyan Han, Erica Tobin, Josh Bird, Robert Cross, Donna Hernandez, Annette Gould, Clare Birch, Simone Gandhi, Maher K. Blood Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL Cell Biology Hematology Immunology Biochemistry |
| author_sort |
vari, frank |
| spelling |
Vari, Frank Arpon, David Keane, Colm Hertzberg, Mark S. Talaulikar, Dipti Jain, Sanjiv Cui, Qingyan Han, Erica Tobin, Josh Bird, Robert Cross, Donna Hernandez, Annette Gould, Clare Birch, Simone Gandhi, Maher K. 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2017-07-796342 <jats:title>Key Points</jats:title> <jats:p>Expansion of PD-1+ CD3−CD56hiCD16-ve NK cells and PD-L1+ monocytes/macrophages is more prominent in cHL than DLBCL. PD-1 blockade reverses the immune evasion mediated by the interaction of PD-1+ NK cells and PD-L1+ monocytes/macrophages.</jats:p> Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL Blood |
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10.1182/blood-2017-07-796342 |
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American Society of Hematology, 2018 |
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American Society of Hematology, 2018 |
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0006-4971 1528-0020 |
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| title |
Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| title_unstemmed |
Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| title_full |
Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| title_fullStr |
Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| title_full_unstemmed |
Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| title_short |
Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| title_sort |
immune evasion via pd-1/pd-l1 on nk cells and monocyte/macrophages is more prominent in hodgkin lymphoma than dlbcl |
| topic |
Cell Biology Hematology Immunology Biochemistry |
| url |
http://dx.doi.org/10.1182/blood-2017-07-796342 |
| publishDate |
2018 |
| physical |
1809-1819 |
| description |
<jats:title>Key Points</jats:title>
<jats:p>Expansion of PD-1+ CD3−CD56hiCD16-ve NK cells and PD-L1+ monocytes/macrophages is more prominent in cHL than DLBCL. PD-1 blockade reverses the immune evasion mediated by the interaction of PD-1+ NK cells and PD-L1+ monocytes/macrophages.</jats:p> |
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| author | Vari, Frank, Arpon, David, Keane, Colm, Hertzberg, Mark S., Talaulikar, Dipti, Jain, Sanjiv, Cui, Qingyan, Han, Erica, Tobin, Josh, Bird, Robert, Cross, Donna, Hernandez, Annette, Gould, Clare, Birch, Simone, Gandhi, Maher K. |
| author_facet | Vari, Frank, Arpon, David, Keane, Colm, Hertzberg, Mark S., Talaulikar, Dipti, Jain, Sanjiv, Cui, Qingyan, Han, Erica, Tobin, Josh, Bird, Robert, Cross, Donna, Hernandez, Annette, Gould, Clare, Birch, Simone, Gandhi, Maher K., Vari, Frank, Arpon, David, Keane, Colm, Hertzberg, Mark S., Talaulikar, Dipti, Jain, Sanjiv, Cui, Qingyan, Han, Erica, Tobin, Josh, Bird, Robert, Cross, Donna, Hernandez, Annette, Gould, Clare, Birch, Simone, Gandhi, Maher K. |
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| description | <jats:title>Key Points</jats:title> <jats:p>Expansion of PD-1+ CD3−CD56hiCD16-ve NK cells and PD-L1+ monocytes/macrophages is more prominent in cHL than DLBCL. PD-1 blockade reverses the immune evasion mediated by the interaction of PD-1+ NK cells and PD-L1+ monocytes/macrophages.</jats:p> |
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| imprint_str_mv | American Society of Hematology, 2018 |
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| spelling | Vari, Frank Arpon, David Keane, Colm Hertzberg, Mark S. Talaulikar, Dipti Jain, Sanjiv Cui, Qingyan Han, Erica Tobin, Josh Bird, Robert Cross, Donna Hernandez, Annette Gould, Clare Birch, Simone Gandhi, Maher K. 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2017-07-796342 <jats:title>Key Points</jats:title> <jats:p>Expansion of PD-1+ CD3−CD56hiCD16-ve NK cells and PD-L1+ monocytes/macrophages is more prominent in cHL than DLBCL. PD-1 blockade reverses the immune evasion mediated by the interaction of PD-1+ NK cells and PD-L1+ monocytes/macrophages.</jats:p> Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL Blood |
| spellingShingle | Vari, Frank, Arpon, David, Keane, Colm, Hertzberg, Mark S., Talaulikar, Dipti, Jain, Sanjiv, Cui, Qingyan, Han, Erica, Tobin, Josh, Bird, Robert, Cross, Donna, Hernandez, Annette, Gould, Clare, Birch, Simone, Gandhi, Maher K., Blood, Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL, Cell Biology, Hematology, Immunology, Biochemistry |
| title | Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| title_full | Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| title_fullStr | Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| title_full_unstemmed | Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| title_short | Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| title_sort | immune evasion via pd-1/pd-l1 on nk cells and monocyte/macrophages is more prominent in hodgkin lymphoma than dlbcl |
| title_unstemmed | Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL |
| topic | Cell Biology, Hematology, Immunology, Biochemistry |
| url | http://dx.doi.org/10.1182/blood-2017-07-796342 |