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Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model
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Zeitschriftentitel: | Blood |
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Personen und Körperschaften: | , , , , , , , , , , , , , , , |
In: | Blood, 124, 2014, 22, S. 3250-3259 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
American Society of Hematology
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Schlagwörter: |
author_facet |
Reagan, Michaela R. Mishima, Yuji Glavey, Siobhan V. Zhang, Yong Manier, Salomon Lu, Zhi Ning Memarzadeh, Masoumeh Zhang, Yu Sacco, Antonio Aljawai, Yosra Shi, Jiantao Tai, Yu-Tzu Ready, John E. Kaplan, David L. Roccaro, Aldo M. Ghobrial, Irene M. Reagan, Michaela R. Mishima, Yuji Glavey, Siobhan V. Zhang, Yong Manier, Salomon Lu, Zhi Ning Memarzadeh, Masoumeh Zhang, Yu Sacco, Antonio Aljawai, Yosra Shi, Jiantao Tai, Yu-Tzu Ready, John E. Kaplan, David L. Roccaro, Aldo M. Ghobrial, Irene M. |
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author |
Reagan, Michaela R. Mishima, Yuji Glavey, Siobhan V. Zhang, Yong Manier, Salomon Lu, Zhi Ning Memarzadeh, Masoumeh Zhang, Yu Sacco, Antonio Aljawai, Yosra Shi, Jiantao Tai, Yu-Tzu Ready, John E. Kaplan, David L. Roccaro, Aldo M. Ghobrial, Irene M. |
spellingShingle |
Reagan, Michaela R. Mishima, Yuji Glavey, Siobhan V. Zhang, Yong Manier, Salomon Lu, Zhi Ning Memarzadeh, Masoumeh Zhang, Yu Sacco, Antonio Aljawai, Yosra Shi, Jiantao Tai, Yu-Tzu Ready, John E. Kaplan, David L. Roccaro, Aldo M. Ghobrial, Irene M. Blood Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model Cell Biology Hematology Immunology Biochemistry |
author_sort |
reagan, michaela r. |
spelling |
Reagan, Michaela R. Mishima, Yuji Glavey, Siobhan V. Zhang, Yong Manier, Salomon Lu, Zhi Ning Memarzadeh, Masoumeh Zhang, Yu Sacco, Antonio Aljawai, Yosra Shi, Jiantao Tai, Yu-Tzu Ready, John E. Kaplan, David L. Roccaro, Aldo M. Ghobrial, Irene M. 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2014-02-558007 <jats:title>Key Points</jats:title> <jats:p>3D bone marrow niche model recapitulates in vivo interactions of tumor and bone cells in a more biologically relevant system than in 2D. Differential expression levels of miRs in MSCs provide novel insights into mechanisms of regulation of osteoblasts in multiple myeloma.</jats:p> Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model Blood |
doi_str_mv |
10.1182/blood-2014-02-558007 |
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Biologie Medizin Chemie und Pharmazie |
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American Society of Hematology, 2014 |
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American Society of Hematology, 2014 |
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American Society of Hematology |
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Blood |
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49 |
title |
Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
title_unstemmed |
Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
title_full |
Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
title_fullStr |
Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
title_full_unstemmed |
Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
title_short |
Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
title_sort |
investigating osteogenic differentiation in multiple myeloma using a novel 3d bone marrow niche model |
topic |
Cell Biology Hematology Immunology Biochemistry |
url |
http://dx.doi.org/10.1182/blood-2014-02-558007 |
publishDate |
2014 |
physical |
3250-3259 |
description |
<jats:title>Key Points</jats:title>
<jats:p>3D bone marrow niche model recapitulates in vivo interactions of tumor and bone cells in a more biologically relevant system than in 2D. Differential expression levels of miRs in MSCs provide novel insights into mechanisms of regulation of osteoblasts in multiple myeloma.</jats:p> |
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author | Reagan, Michaela R., Mishima, Yuji, Glavey, Siobhan V., Zhang, Yong, Manier, Salomon, Lu, Zhi Ning, Memarzadeh, Masoumeh, Zhang, Yu, Sacco, Antonio, Aljawai, Yosra, Shi, Jiantao, Tai, Yu-Tzu, Ready, John E., Kaplan, David L., Roccaro, Aldo M., Ghobrial, Irene M. |
author_facet | Reagan, Michaela R., Mishima, Yuji, Glavey, Siobhan V., Zhang, Yong, Manier, Salomon, Lu, Zhi Ning, Memarzadeh, Masoumeh, Zhang, Yu, Sacco, Antonio, Aljawai, Yosra, Shi, Jiantao, Tai, Yu-Tzu, Ready, John E., Kaplan, David L., Roccaro, Aldo M., Ghobrial, Irene M., Reagan, Michaela R., Mishima, Yuji, Glavey, Siobhan V., Zhang, Yong, Manier, Salomon, Lu, Zhi Ning, Memarzadeh, Masoumeh, Zhang, Yu, Sacco, Antonio, Aljawai, Yosra, Shi, Jiantao, Tai, Yu-Tzu, Ready, John E., Kaplan, David L., Roccaro, Aldo M., Ghobrial, Irene M. |
author_sort | reagan, michaela r. |
container_issue | 22 |
container_start_page | 3250 |
container_title | Blood |
container_volume | 124 |
description | <jats:title>Key Points</jats:title> <jats:p>3D bone marrow niche model recapitulates in vivo interactions of tumor and bone cells in a more biologically relevant system than in 2D. Differential expression levels of miRs in MSCs provide novel insights into mechanisms of regulation of osteoblasts in multiple myeloma.</jats:p> |
doi_str_mv | 10.1182/blood-2014-02-558007 |
facet_avail | Online, Free |
finc_class_facet | Biologie, Medizin, Chemie und Pharmazie |
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publisher | American Society of Hematology |
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series | Blood |
source_id | 49 |
spelling | Reagan, Michaela R. Mishima, Yuji Glavey, Siobhan V. Zhang, Yong Manier, Salomon Lu, Zhi Ning Memarzadeh, Masoumeh Zhang, Yu Sacco, Antonio Aljawai, Yosra Shi, Jiantao Tai, Yu-Tzu Ready, John E. Kaplan, David L. Roccaro, Aldo M. Ghobrial, Irene M. 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2014-02-558007 <jats:title>Key Points</jats:title> <jats:p>3D bone marrow niche model recapitulates in vivo interactions of tumor and bone cells in a more biologically relevant system than in 2D. Differential expression levels of miRs in MSCs provide novel insights into mechanisms of regulation of osteoblasts in multiple myeloma.</jats:p> Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model Blood |
spellingShingle | Reagan, Michaela R., Mishima, Yuji, Glavey, Siobhan V., Zhang, Yong, Manier, Salomon, Lu, Zhi Ning, Memarzadeh, Masoumeh, Zhang, Yu, Sacco, Antonio, Aljawai, Yosra, Shi, Jiantao, Tai, Yu-Tzu, Ready, John E., Kaplan, David L., Roccaro, Aldo M., Ghobrial, Irene M., Blood, Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model, Cell Biology, Hematology, Immunology, Biochemistry |
title | Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
title_full | Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
title_fullStr | Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
title_full_unstemmed | Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
title_short | Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
title_sort | investigating osteogenic differentiation in multiple myeloma using a novel 3d bone marrow niche model |
title_unstemmed | Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model |
topic | Cell Biology, Hematology, Immunology, Biochemistry |
url | http://dx.doi.org/10.1182/blood-2014-02-558007 |