Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model

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Bibliographische Detailangaben
Zeitschriftentitel:	Blood
Personen und Körperschaften:	Reagan, Michaela R., Mishima, Yuji, Glavey, Siobhan V., Zhang, Yong, Manier, Salomon, Lu, Zhi Ning, Memarzadeh, Masoumeh, Zhang, Yu, Sacco, Antonio, Aljawai, Yosra, Shi, Jiantao, Tai, Yu-Tzu, Ready, John E., Kaplan, David L., Roccaro, Aldo M., Ghobrial, Irene M.
In:	Blood, 124, 2014, 22, S. 3250-3259
Format:	E-Article
Sprache:	Englisch
veröffentlicht:	American Society of Hematology
Schlagwörter:	Cell Biology Hematology Immunology Biochemistry

Details
Zusammenfassung:	<jats:title>Key Points</jats:title> <jats:p>3D bone marrow niche model recapitulates in vivo interactions of tumor and bone cells in a more biologically relevant system than in 2D. Differential expression levels of miRs in MSCs provide novel insights into mechanisms of regulation of osteoblasts in multiple myeloma.</jats:p>
Umfang:	3250-3259
ISSN:	0006-4971 1528-0020
DOI:	10.1182/blood-2014-02-558007