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ChIP-chip Comes of Age for Genome-wide Functional Analysis
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| Zeitschriftentitel: | Cancer Research |
|---|---|
| Personen und Körperschaften: | , , , |
| In: | Cancer Research, 66, 2006, 14, S. 6899-6902 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Association for Cancer Research (AACR)
|
| Schlagwörter: |
| author_facet |
Wu, Jiejun Smith, Laura T. Plass, Christoph Huang, Tim H-M. Wu, Jiejun Smith, Laura T. Plass, Christoph Huang, Tim H-M. |
|---|---|
| author |
Wu, Jiejun Smith, Laura T. Plass, Christoph Huang, Tim H-M. |
| spellingShingle |
Wu, Jiejun Smith, Laura T. Plass, Christoph Huang, Tim H-M. Cancer Research ChIP-chip Comes of Age for Genome-wide Functional Analysis Cancer Research Oncology |
| author_sort |
wu, jiejun |
| spelling |
Wu, Jiejun Smith, Laura T. Plass, Christoph Huang, Tim H-M. 0008-5472 1538-7445 American Association for Cancer Research (AACR) Cancer Research Oncology http://dx.doi.org/10.1158/0008-5472.can-06-0276 <jats:title>Abstract</jats:title> <jats:p>In the post-genome era, attention has focused on the functions of genome sequences and how they are regulated. The emerging epigenomic changes and the interactions between cis-acting elements and protein factors may play a central role in gene regulation. To understand the crosstalk between DNA and protein on a genome-wide scale, one emerging technique, called ChIP-chip, takes the strategy of combining chromatin immunoprecipitation with microarray. This new high-throughput strategy helps screen the targets of critical transcription factors and profile the genome-wide distribution of histone modifications, which will enable the feasibility of conducting a large-scale study, such as the Human Epigenome Project. (Cancer Res 2006; 66(14): 6899-902)</jats:p> ChIP-chip Comes of Age for Genome-wide Functional Analysis Cancer Research |
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American Association for Cancer Research (AACR), 2006 |
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American Association for Cancer Research (AACR), 2006 |
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0008-5472 1538-7445 |
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Cancer Research |
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| title |
ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| title_unstemmed |
ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| title_full |
ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| title_fullStr |
ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| title_full_unstemmed |
ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| title_short |
ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| title_sort |
chip-chip comes of age for genome-wide functional analysis |
| topic |
Cancer Research Oncology |
| url |
http://dx.doi.org/10.1158/0008-5472.can-06-0276 |
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2006 |
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6899-6902 |
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<jats:title>Abstract</jats:title>
<jats:p>In the post-genome era, attention has focused on the functions of genome sequences and how they are regulated. The emerging epigenomic changes and the interactions between cis-acting elements and protein factors may play a central role in gene regulation. To understand the crosstalk between DNA and protein on a genome-wide scale, one emerging technique, called ChIP-chip, takes the strategy of combining chromatin immunoprecipitation with microarray. This new high-throughput strategy helps screen the targets of critical transcription factors and profile the genome-wide distribution of histone modifications, which will enable the feasibility of conducting a large-scale study, such as the Human Epigenome Project. (Cancer Res 2006; 66(14): 6899-902)</jats:p> |
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| author | Wu, Jiejun, Smith, Laura T., Plass, Christoph, Huang, Tim H-M. |
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| description | <jats:title>Abstract</jats:title> <jats:p>In the post-genome era, attention has focused on the functions of genome sequences and how they are regulated. The emerging epigenomic changes and the interactions between cis-acting elements and protein factors may play a central role in gene regulation. To understand the crosstalk between DNA and protein on a genome-wide scale, one emerging technique, called ChIP-chip, takes the strategy of combining chromatin immunoprecipitation with microarray. This new high-throughput strategy helps screen the targets of critical transcription factors and profile the genome-wide distribution of histone modifications, which will enable the feasibility of conducting a large-scale study, such as the Human Epigenome Project. (Cancer Res 2006; 66(14): 6899-902)</jats:p> |
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| imprint_str_mv | American Association for Cancer Research (AACR), 2006 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Zi4, DE-Gla1, DE-15, DE-Pl11, DE-Rs1, DE-14, DE-105, DE-Ch1, DE-L229 |
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| spelling | Wu, Jiejun Smith, Laura T. Plass, Christoph Huang, Tim H-M. 0008-5472 1538-7445 American Association for Cancer Research (AACR) Cancer Research Oncology http://dx.doi.org/10.1158/0008-5472.can-06-0276 <jats:title>Abstract</jats:title> <jats:p>In the post-genome era, attention has focused on the functions of genome sequences and how they are regulated. The emerging epigenomic changes and the interactions between cis-acting elements and protein factors may play a central role in gene regulation. To understand the crosstalk between DNA and protein on a genome-wide scale, one emerging technique, called ChIP-chip, takes the strategy of combining chromatin immunoprecipitation with microarray. This new high-throughput strategy helps screen the targets of critical transcription factors and profile the genome-wide distribution of histone modifications, which will enable the feasibility of conducting a large-scale study, such as the Human Epigenome Project. (Cancer Res 2006; 66(14): 6899-902)</jats:p> ChIP-chip Comes of Age for Genome-wide Functional Analysis Cancer Research |
| spellingShingle | Wu, Jiejun, Smith, Laura T., Plass, Christoph, Huang, Tim H-M., Cancer Research, ChIP-chip Comes of Age for Genome-wide Functional Analysis, Cancer Research, Oncology |
| title | ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| title_full | ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| title_fullStr | ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| title_full_unstemmed | ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| title_short | ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| title_sort | chip-chip comes of age for genome-wide functional analysis |
| title_unstemmed | ChIP-chip Comes of Age for Genome-wide Functional Analysis |
| topic | Cancer Research, Oncology |
| url | http://dx.doi.org/10.1158/0008-5472.can-06-0276 |