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Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus)
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| Zeitschriftentitel: | Genetical Research |
|---|---|
| Personen und Körperschaften: | , |
| In: | Genetical Research, 57, 1991, 1, S. 61-70 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Hindawi Limited
|
| Schlagwörter: |
| author_facet |
von Deimling, O. H. Gaa, A. von Deimling, O. H. Gaa, A. |
|---|---|
| author |
von Deimling, O. H. Gaa, A. |
| spellingShingle |
von Deimling, O. H. Gaa, A. Genetical Research Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) Genetics General Medicine |
| author_sort |
von deimling, o. h. |
| spelling |
von Deimling, O. H. Gaa, A. 0016-6723 1469-5073 Hindawi Limited Genetics General Medicine http://dx.doi.org/10.1017/s0016672300029050 <jats:title>Summary</jats:title><jats:p>Esterase-27A (ES-27A) was characterized in strain A/WySnA by a cascade of seven bands seen after disc electrophoresis of serum and subsequent staining for esterase. ES-27A catalyses the hydrolysis of thiocholine butyrate and is strongly inhibited by 100 μ<jats:sc>m</jats:sc> tetraisopropyl pyrophosphamide (isoOMPA). Hence, the enzyme was concluded to be a cholinesterase EC 3.1.1.8. A heat-labile form termed ES-27B was represented by strain AKR/Han. From a three-point cross (AKR/Han, A/Wy) and a five-point cross (AKR/Han, SEG/1), the gene order on chromosome 3 was concluded to be centromere–<jats:italic>Car-2–Es-26–Es-27–Amy-1–Adh-1</jats:italic>.</jats:p> Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (<i>Mus musculus</i>) Genetical Research |
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10.1017/s0016672300029050 |
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Hindawi Limited, 1991 |
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Hindawi Limited, 1991 |
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1991 |
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Genetical Research |
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| title |
Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| title_unstemmed |
Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| title_full |
Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| title_fullStr |
Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| title_full_unstemmed |
Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| title_short |
Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| title_sort |
biochemical and genetic characterization of esterase-27 (es-27), the major plasma cholinesterase of the house mouse (<i>mus musculus</i>) |
| topic |
Genetics General Medicine |
| url |
http://dx.doi.org/10.1017/s0016672300029050 |
| publishDate |
1991 |
| physical |
61-70 |
| description |
<jats:title>Summary</jats:title><jats:p>Esterase-27A (ES-27A) was characterized in strain A/WySnA by a cascade of seven bands seen after disc electrophoresis of serum and subsequent staining for esterase. ES-27A catalyses the hydrolysis of thiocholine butyrate and is strongly inhibited by 100 μ<jats:sc>m</jats:sc> tetraisopropyl pyrophosphamide (isoOMPA). Hence, the enzyme was concluded to be a cholinesterase EC 3.1.1.8. A heat-labile form termed ES-27B was represented by strain AKR/Han. From a three-point cross (AKR/Han, A/Wy) and a five-point cross (AKR/Han, SEG/1), the gene order on chromosome 3 was concluded to be centromere–<jats:italic>Car-2–Es-26–Es-27–Amy-1–Adh-1</jats:italic>.</jats:p> |
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| author | von Deimling, O. H., Gaa, A. |
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| description | <jats:title>Summary</jats:title><jats:p>Esterase-27A (ES-27A) was characterized in strain A/WySnA by a cascade of seven bands seen after disc electrophoresis of serum and subsequent staining for esterase. ES-27A catalyses the hydrolysis of thiocholine butyrate and is strongly inhibited by 100 μ<jats:sc>m</jats:sc> tetraisopropyl pyrophosphamide (isoOMPA). Hence, the enzyme was concluded to be a cholinesterase EC 3.1.1.8. A heat-labile form termed ES-27B was represented by strain AKR/Han. From a three-point cross (AKR/Han, A/Wy) and a five-point cross (AKR/Han, SEG/1), the gene order on chromosome 3 was concluded to be centromere–<jats:italic>Car-2–Es-26–Es-27–Amy-1–Adh-1</jats:italic>.</jats:p> |
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| imprint | Hindawi Limited, 1991 |
| imprint_str_mv | Hindawi Limited, 1991 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229 |
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| physical | 61-70 |
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| series | Genetical Research |
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| spelling | von Deimling, O. H. Gaa, A. 0016-6723 1469-5073 Hindawi Limited Genetics General Medicine http://dx.doi.org/10.1017/s0016672300029050 <jats:title>Summary</jats:title><jats:p>Esterase-27A (ES-27A) was characterized in strain A/WySnA by a cascade of seven bands seen after disc electrophoresis of serum and subsequent staining for esterase. ES-27A catalyses the hydrolysis of thiocholine butyrate and is strongly inhibited by 100 μ<jats:sc>m</jats:sc> tetraisopropyl pyrophosphamide (isoOMPA). Hence, the enzyme was concluded to be a cholinesterase EC 3.1.1.8. A heat-labile form termed ES-27B was represented by strain AKR/Han. From a three-point cross (AKR/Han, A/Wy) and a five-point cross (AKR/Han, SEG/1), the gene order on chromosome 3 was concluded to be centromere–<jats:italic>Car-2–Es-26–Es-27–Amy-1–Adh-1</jats:italic>.</jats:p> Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (<i>Mus musculus</i>) Genetical Research |
| spellingShingle | von Deimling, O. H., Gaa, A., Genetical Research, Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus), Genetics, General Medicine |
| title | Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| title_full | Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| title_fullStr | Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| title_full_unstemmed | Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| title_short | Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| title_sort | biochemical and genetic characterization of esterase-27 (es-27), the major plasma cholinesterase of the house mouse (<i>mus musculus</i>) |
| title_unstemmed | Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus) |
| topic | Genetics, General Medicine |
| url | http://dx.doi.org/10.1017/s0016672300029050 |