author_facet Hoheisel, Jörg D.
Lehrach, Hans
Hoheisel, Jörg D.
Lehrach, Hans
author Hoheisel, Jörg D.
Lehrach, Hans
spellingShingle Hoheisel, Jörg D.
Lehrach, Hans
FEBS Letters
Use of reference libraries and hybridisation fingerprinting for relational genome analysis
Cell Biology
Genetics
Molecular Biology
Biochemistry
Structural Biology
Biophysics
author_sort hoheisel, jörg d.
spelling Hoheisel, Jörg D. Lehrach, Hans 0014-5793 1873-3468 Wiley Cell Biology Genetics Molecular Biology Biochemistry Structural Biology Biophysics http://dx.doi.org/10.1016/0014-5793(93)81426-z <jats:p>The concept of relational genome analysis by hybridisation has been developed into a working system. Various genomic and cDNA libraries have been generated and are distributed via a reference system. Analysis procedures have been tested successfully in the mapping of the entire <jats:italic>Schizosaccharomyces pombe</jats:italic> genome. In another test‐case for their refinement, analyses on the <jats:italic>Drosophila</jats:italic> genome are well under way. Human and mouse libraries are being studied on all levels, from generating YAC maps to partially sequencing representative cDNA libraries. The automation of the involved processes and the development of improved image detection and analysis are well advanced.</jats:p> Use of reference libraries and hybridisation fingerprinting for relational genome analysis FEBS Letters
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title Use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_unstemmed Use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_full Use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_fullStr Use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_full_unstemmed Use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_short Use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_sort use of reference libraries and hybridisation fingerprinting for relational genome analysis
topic Cell Biology
Genetics
Molecular Biology
Biochemistry
Structural Biology
Biophysics
url http://dx.doi.org/10.1016/0014-5793(93)81426-z
publishDate 1993
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description <jats:p>The concept of relational genome analysis by hybridisation has been developed into a working system. Various genomic and cDNA libraries have been generated and are distributed via a reference system. Analysis procedures have been tested successfully in the mapping of the entire <jats:italic>Schizosaccharomyces pombe</jats:italic> genome. In another test‐case for their refinement, analyses on the <jats:italic>Drosophila</jats:italic> genome are well under way. Human and mouse libraries are being studied on all levels, from generating YAC maps to partially sequencing representative cDNA libraries. The automation of the involved processes and the development of improved image detection and analysis are well advanced.</jats:p>
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author Hoheisel, Jörg D., Lehrach, Hans
author_facet Hoheisel, Jörg D., Lehrach, Hans, Hoheisel, Jörg D., Lehrach, Hans
author_sort hoheisel, jörg d.
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spelling Hoheisel, Jörg D. Lehrach, Hans 0014-5793 1873-3468 Wiley Cell Biology Genetics Molecular Biology Biochemistry Structural Biology Biophysics http://dx.doi.org/10.1016/0014-5793(93)81426-z <jats:p>The concept of relational genome analysis by hybridisation has been developed into a working system. Various genomic and cDNA libraries have been generated and are distributed via a reference system. Analysis procedures have been tested successfully in the mapping of the entire <jats:italic>Schizosaccharomyces pombe</jats:italic> genome. In another test‐case for their refinement, analyses on the <jats:italic>Drosophila</jats:italic> genome are well under way. Human and mouse libraries are being studied on all levels, from generating YAC maps to partially sequencing representative cDNA libraries. The automation of the involved processes and the development of improved image detection and analysis are well advanced.</jats:p> Use of reference libraries and hybridisation fingerprinting for relational genome analysis FEBS Letters
spellingShingle Hoheisel, Jörg D., Lehrach, Hans, FEBS Letters, Use of reference libraries and hybridisation fingerprinting for relational genome analysis, Cell Biology, Genetics, Molecular Biology, Biochemistry, Structural Biology, Biophysics
title Use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_full Use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_fullStr Use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_full_unstemmed Use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_short Use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_sort use of reference libraries and hybridisation fingerprinting for relational genome analysis
title_unstemmed Use of reference libraries and hybridisation fingerprinting for relational genome analysis
topic Cell Biology, Genetics, Molecular Biology, Biochemistry, Structural Biology, Biophysics
url http://dx.doi.org/10.1016/0014-5793(93)81426-z