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Liver Injury and Failure in Critical Illness
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| Zeitschriftentitel: | Hepatology |
|---|---|
| Personen und Körperschaften: | , , , |
| In: | Hepatology, 70, 2019, 6, S. 2204-2215 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Ovid Technologies (Wolters Kluwer Health)
|
| Schlagwörter: |
| author_facet |
Horvatits, Thomas Drolz, Andreas Trauner, Michael Fuhrmann, Valentin Horvatits, Thomas Drolz, Andreas Trauner, Michael Fuhrmann, Valentin |
|---|---|
| author |
Horvatits, Thomas Drolz, Andreas Trauner, Michael Fuhrmann, Valentin |
| spellingShingle |
Horvatits, Thomas Drolz, Andreas Trauner, Michael Fuhrmann, Valentin Hepatology Liver Injury and Failure in Critical Illness Hepatology |
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horvatits, thomas |
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Horvatits, Thomas Drolz, Andreas Trauner, Michael Fuhrmann, Valentin 0270-9139 1527-3350 Ovid Technologies (Wolters Kluwer Health) Hepatology http://dx.doi.org/10.1002/hep.30824 <jats:p>The frequency of acquired liver injury and failure in critical illness has been significantly increasing over recent decades. Currently, liver injury and failure are observed in up to 20% of patients in intensive care units and are associated with significantly increased morbidity and mortality. Secondary forms of liver injury in critical illness are divided primarily into cholestatic, hypoxic, or mixed forms. Therefore, sufficient knowledge of underlying alterations (e.g., hemodynamic, inflammatory, or drug induced) is key to a better understanding of clinical manifestations, prognostic implications, as well as diagnostic and therapeutic options of acquired liver injury and failure. This review provides a structured approach for the evaluation and treatment of acquired liver injury and failure in critically ill patients.</jats:p> Liver Injury and Failure in Critical Illness Hepatology |
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Liver Injury and Failure in Critical Illness |
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Liver Injury and Failure in Critical Illness |
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Liver Injury and Failure in Critical Illness |
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Liver Injury and Failure in Critical Illness |
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Liver Injury and Failure in Critical Illness |
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liver injury and failure in critical illness |
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Hepatology |
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http://dx.doi.org/10.1002/hep.30824 |
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2019 |
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<jats:p>The frequency of acquired liver injury and failure in critical illness has been significantly increasing over recent decades. Currently, liver injury and failure are observed in up to 20% of patients in intensive care units and are associated with significantly increased morbidity and mortality. Secondary forms of liver injury in critical illness are divided primarily into cholestatic, hypoxic, or mixed forms. Therefore, sufficient knowledge of underlying alterations (e.g., hemodynamic, inflammatory, or drug induced) is key to a better understanding of clinical manifestations, prognostic implications, as well as diagnostic and therapeutic options of acquired liver injury and failure. This review provides a structured approach for the evaluation and treatment of acquired liver injury and failure in critically ill patients.</jats:p> |
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| author | Horvatits, Thomas, Drolz, Andreas, Trauner, Michael, Fuhrmann, Valentin |
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| description | <jats:p>The frequency of acquired liver injury and failure in critical illness has been significantly increasing over recent decades. Currently, liver injury and failure are observed in up to 20% of patients in intensive care units and are associated with significantly increased morbidity and mortality. Secondary forms of liver injury in critical illness are divided primarily into cholestatic, hypoxic, or mixed forms. Therefore, sufficient knowledge of underlying alterations (e.g., hemodynamic, inflammatory, or drug induced) is key to a better understanding of clinical manifestations, prognostic implications, as well as diagnostic and therapeutic options of acquired liver injury and failure. This review provides a structured approach for the evaluation and treatment of acquired liver injury and failure in critically ill patients.</jats:p> |
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| spelling | Horvatits, Thomas Drolz, Andreas Trauner, Michael Fuhrmann, Valentin 0270-9139 1527-3350 Ovid Technologies (Wolters Kluwer Health) Hepatology http://dx.doi.org/10.1002/hep.30824 <jats:p>The frequency of acquired liver injury and failure in critical illness has been significantly increasing over recent decades. Currently, liver injury and failure are observed in up to 20% of patients in intensive care units and are associated with significantly increased morbidity and mortality. Secondary forms of liver injury in critical illness are divided primarily into cholestatic, hypoxic, or mixed forms. Therefore, sufficient knowledge of underlying alterations (e.g., hemodynamic, inflammatory, or drug induced) is key to a better understanding of clinical manifestations, prognostic implications, as well as diagnostic and therapeutic options of acquired liver injury and failure. This review provides a structured approach for the evaluation and treatment of acquired liver injury and failure in critically ill patients.</jats:p> Liver Injury and Failure in Critical Illness Hepatology |
| spellingShingle | Horvatits, Thomas, Drolz, Andreas, Trauner, Michael, Fuhrmann, Valentin, Hepatology, Liver Injury and Failure in Critical Illness, Hepatology |
| title | Liver Injury and Failure in Critical Illness |
| title_full | Liver Injury and Failure in Critical Illness |
| title_fullStr | Liver Injury and Failure in Critical Illness |
| title_full_unstemmed | Liver Injury and Failure in Critical Illness |
| title_short | Liver Injury and Failure in Critical Illness |
| title_sort | liver injury and failure in critical illness |
| title_unstemmed | Liver Injury and Failure in Critical Illness |
| topic | Hepatology |
| url | http://dx.doi.org/10.1002/hep.30824 |