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Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein
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| Zeitschriftentitel: | Molecular Biology of the Cell |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , , , |
| In: | Molecular Biology of the Cell, 32, 2021, 5, S. 376-390 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Society for Cell Biology (ASCB)
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| Schlagwörter: |
| author_facet |
Nouri-Nejad, Daniel O’Donnell, Brooke L. Patil, Chetan S. Sanchez-Pupo, Rafael E. Johnston, Danielle Sayedyahossein, Samar Jurcic, Kristina Lau, Rebecca Gyenis, Laszlo Litchfield, David W. Jackson, Michael F. Gloor, Gregory B. Penuela, Silvia Nouri-Nejad, Daniel O’Donnell, Brooke L. Patil, Chetan S. Sanchez-Pupo, Rafael E. Johnston, Danielle Sayedyahossein, Samar Jurcic, Kristina Lau, Rebecca Gyenis, Laszlo Litchfield, David W. Jackson, Michael F. Gloor, Gregory B. Penuela, Silvia |
|---|---|
| author |
Nouri-Nejad, Daniel O’Donnell, Brooke L. Patil, Chetan S. Sanchez-Pupo, Rafael E. Johnston, Danielle Sayedyahossein, Samar Jurcic, Kristina Lau, Rebecca Gyenis, Laszlo Litchfield, David W. Jackson, Michael F. Gloor, Gregory B. Penuela, Silvia |
| spellingShingle |
Nouri-Nejad, Daniel O’Donnell, Brooke L. Patil, Chetan S. Sanchez-Pupo, Rafael E. Johnston, Danielle Sayedyahossein, Samar Jurcic, Kristina Lau, Rebecca Gyenis, Laszlo Litchfield, David W. Jackson, Michael F. Gloor, Gregory B. Penuela, Silvia Molecular Biology of the Cell Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein Cell Biology Molecular Biology |
| author_sort |
nouri-nejad, daniel |
| spelling |
Nouri-Nejad, Daniel O’Donnell, Brooke L. Patil, Chetan S. Sanchez-Pupo, Rafael E. Johnston, Danielle Sayedyahossein, Samar Jurcic, Kristina Lau, Rebecca Gyenis, Laszlo Litchfield, David W. Jackson, Michael F. Gloor, Gregory B. Penuela, Silvia 1059-1524 1939-4586 American Society for Cell Biology (ASCB) Cell Biology Molecular Biology http://dx.doi.org/10.1091/mbc.e19-10-0585 <jats:p> In this study, we discovered the first mutation in a phosphorylation site of pannexin 1 (PANX1) that affects phosphorylation, glycosylation, and trafficking of PANX1 channels in a melanoma patient tumor. We also reported on the ancestral allele of PANX1 that is the most representative variant within human populations. </jats:p> Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein Molecular Biology of the Cell |
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| title |
Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_unstemmed |
Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_full |
Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_fullStr |
Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_full_unstemmed |
Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_short |
Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_sort |
pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| topic |
Cell Biology Molecular Biology |
| url |
http://dx.doi.org/10.1091/mbc.e19-10-0585 |
| publishDate |
2021 |
| physical |
376-390 |
| description |
<jats:p> In this study, we discovered the first mutation in a phosphorylation site of pannexin 1 (PANX1) that affects phosphorylation, glycosylation, and trafficking of PANX1 channels in a melanoma patient tumor. We also reported on the ancestral allele of PANX1 that is the most representative variant within human populations. </jats:p> |
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| author | Nouri-Nejad, Daniel, O’Donnell, Brooke L., Patil, Chetan S., Sanchez-Pupo, Rafael E., Johnston, Danielle, Sayedyahossein, Samar, Jurcic, Kristina, Lau, Rebecca, Gyenis, Laszlo, Litchfield, David W., Jackson, Michael F., Gloor, Gregory B., Penuela, Silvia |
| author_facet | Nouri-Nejad, Daniel, O’Donnell, Brooke L., Patil, Chetan S., Sanchez-Pupo, Rafael E., Johnston, Danielle, Sayedyahossein, Samar, Jurcic, Kristina, Lau, Rebecca, Gyenis, Laszlo, Litchfield, David W., Jackson, Michael F., Gloor, Gregory B., Penuela, Silvia, Nouri-Nejad, Daniel, O’Donnell, Brooke L., Patil, Chetan S., Sanchez-Pupo, Rafael E., Johnston, Danielle, Sayedyahossein, Samar, Jurcic, Kristina, Lau, Rebecca, Gyenis, Laszlo, Litchfield, David W., Jackson, Michael F., Gloor, Gregory B., Penuela, Silvia |
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| description | <jats:p> In this study, we discovered the first mutation in a phosphorylation site of pannexin 1 (PANX1) that affects phosphorylation, glycosylation, and trafficking of PANX1 channels in a melanoma patient tumor. We also reported on the ancestral allele of PANX1 that is the most representative variant within human populations. </jats:p> |
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| spelling | Nouri-Nejad, Daniel O’Donnell, Brooke L. Patil, Chetan S. Sanchez-Pupo, Rafael E. Johnston, Danielle Sayedyahossein, Samar Jurcic, Kristina Lau, Rebecca Gyenis, Laszlo Litchfield, David W. Jackson, Michael F. Gloor, Gregory B. Penuela, Silvia 1059-1524 1939-4586 American Society for Cell Biology (ASCB) Cell Biology Molecular Biology http://dx.doi.org/10.1091/mbc.e19-10-0585 <jats:p> In this study, we discovered the first mutation in a phosphorylation site of pannexin 1 (PANX1) that affects phosphorylation, glycosylation, and trafficking of PANX1 channels in a melanoma patient tumor. We also reported on the ancestral allele of PANX1 that is the most representative variant within human populations. </jats:p> Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein Molecular Biology of the Cell |
| spellingShingle | Nouri-Nejad, Daniel, O’Donnell, Brooke L., Patil, Chetan S., Sanchez-Pupo, Rafael E., Johnston, Danielle, Sayedyahossein, Samar, Jurcic, Kristina, Lau, Rebecca, Gyenis, Laszlo, Litchfield, David W., Jackson, Michael F., Gloor, Gregory B., Penuela, Silvia, Molecular Biology of the Cell, Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein, Cell Biology, Molecular Biology |
| title | Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_full | Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_fullStr | Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_full_unstemmed | Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_short | Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_sort | pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| title_unstemmed | Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein |
| topic | Cell Biology, Molecular Biology |
| url | http://dx.doi.org/10.1091/mbc.e19-10-0585 |