A case of beta-thalassaemia major resistant to standard treatment

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Bibliographische Detailangaben
Zeitschriftentitel:	Clinical Management Issues
Personen und Körperschaften:	Masera, Nicoletta, Decimi, Valentina, Tavecchia, Luisa, Capra, Marietta, Cazzaniga, Giovanni, Biondi, Andrea, Masera, Giuseppe
In:	Clinical Management Issues, 4, 2010, 2, S. 65-70
Format:	E-Article
Sprache:	Unbestimmt
veröffentlicht:	Seed SRL
Schlagwörter:	Business, Management and Accounting (miscellaneous) Medicine (miscellaneous)

Details
Zusammenfassung:	<jats:p>We report the case of a 22-year-old woman from Albania, with thalassaemia major, in severe clinical condition who could no longer be transfused due to the occurrence of severe, acute, post-transfusional reactions. After 10 years of treatment, she failed to respond to hydroxyurea. When she received thalidomide, haemoglobin levels increased from 3.7 g/dl to 9 g/dl. Since then, at 22 months of follow-up, the therapy is still effective and well tolerated. The case gives the opportunity to describe the clinical use of thalidomide, and its potential in the management of beta-thalassaemia.</jats:p>
Umfang:	65-70
ISSN:	2283-3137 1973-4832
DOI:	10.7175/cmi.v4i2.531