Eintrag weiter verarbeiten
Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep
Gespeichert in:
| Zeitschriftentitel: | Archives Animal Breeding |
|---|---|
| Personen und Körperschaften: | , , , , |
| In: | Archives Animal Breeding, 62, 2019, 2, S. 413-422 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Copernicus GmbH
|
| author_facet |
Ibrahim, Adel H. M. Tzanidakis, Nikolaos Sotiraki, Smaragda Zhou, Huitong Hickford, Jonathan G. H. Ibrahim, Adel H. M. Tzanidakis, Nikolaos Sotiraki, Smaragda Zhou, Huitong Hickford, Jonathan G. H. |
|---|---|
| author |
Ibrahim, Adel H. M. Tzanidakis, Nikolaos Sotiraki, Smaragda Zhou, Huitong Hickford, Jonathan G. H. |
| spellingShingle |
Ibrahim, Adel H. M. Tzanidakis, Nikolaos Sotiraki, Smaragda Zhou, Huitong Hickford, Jonathan G. H. Archives Animal Breeding Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| author_sort |
ibrahim, adel h. m. |
| spelling |
Ibrahim, Adel H. M. Tzanidakis, Nikolaos Sotiraki, Smaragda Zhou, Huitong Hickford, Jonathan G. H. 2363-9822 Copernicus GmbH http://dx.doi.org/10.5194/aab-62-413-2019 <jats:p>Abstract. The aim of this study was to estimate the effect of variation in the fatty acid binding protein 4 gene (FABP4) on milk production traits in Greek Sfakia sheep. Polymerase chain reaction – single-stranded conformational polymorphism (PCR-SSCP) analysis was used to genotype a total of 374 Sfakia ewes for two regions of FABP4 located around exon 2–intron 2 (Region 1) and exon 3–intron 3 (Region 2). Each month, for a period of 6 months, milk samples were collected from the ewes to measure total milk yield, fat content, protein content, lactose content, non-fat solid content, pH, and somatic cell count (SCC). A general linear model was used to test the association between the variation observed in FABP4 and milk production traits. Four gene variants (A1–A4) were found in Region 1 and two variants (C1–C2) were found in Region 2. In the first region, the FABP4 genotype significantly affected (P<0.05) non-fat solid levels, fat content, and SCC. The presence of the A2 variant was significantly associated (P<0.05) with decreased SCC, while the presence of A4 was significantly associated with decreased milk yield (P<0.01), increased non-fat solid content (P<0.05), decreased fat content (P<0.01), increased lactose content (P<0.05), and increased pH (P<0.05). In the second region, FABP4 genotype had an effect (P<0.05) on protein content and the presence of the C2 variant was associated (P<0.05) with increased protein content, decreased SCC, and lower pH. The results suggest an association between variation in ovine FABP4 and milk production traits in Greek Sfakia sheep. Nevertheless, further analyses in independent sheep populations of increased size will strengthen these findings.</jats:p> Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep Archives Animal Breeding |
| doi_str_mv |
10.5194/aab-62-413-2019 |
| facet_avail |
Online Free |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuNTE5NC9hYWItNjItNDEzLTIwMTk |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuNTE5NC9hYWItNjItNDEzLTIwMTk |
| institution |
DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 DE-Ch1 |
| imprint |
Copernicus GmbH, 2019 |
| imprint_str_mv |
Copernicus GmbH, 2019 |
| issn |
2363-9822 |
| issn_str_mv |
2363-9822 |
| language |
English |
| mega_collection |
Copernicus GmbH (CrossRef) |
| match_str |
ibrahim2019identificationoftheassociationbetweenltigtfabp4ltigtgenepolymorphismsandmilkproductiontraitsinsfakiasheep |
| publishDateSort |
2019 |
| publisher |
Copernicus GmbH |
| recordtype |
ai |
| record_format |
ai |
| series |
Archives Animal Breeding |
| source_id |
49 |
| title |
Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title_unstemmed |
Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title_full |
Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title_fullStr |
Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title_full_unstemmed |
Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title_short |
Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title_sort |
identification of the association between <i>fabp4</i> gene polymorphisms and milk production traits in sfakia sheep |
| url |
http://dx.doi.org/10.5194/aab-62-413-2019 |
| publishDate |
2019 |
| physical |
413-422 |
| description |
<jats:p>Abstract. The aim of this study was to estimate the effect of variation in the fatty acid binding protein 4 gene (FABP4) on milk production traits in Greek Sfakia sheep. Polymerase chain reaction – single-stranded conformational polymorphism (PCR-SSCP) analysis was used to genotype a total of 374 Sfakia ewes for two regions of FABP4 located around exon 2–intron 2 (Region 1) and exon 3–intron 3 (Region 2). Each month, for a period of 6 months, milk samples were collected from the ewes to measure total milk yield, fat content, protein content, lactose content, non-fat solid content, pH, and somatic cell count (SCC). A general linear model was used to test the association between the variation observed in FABP4 and milk production traits. Four gene variants (A1–A4) were found in Region 1 and two variants (C1–C2) were found in Region 2. In the first region, the FABP4 genotype significantly affected (P<0.05) non-fat solid levels, fat content, and SCC. The presence of the A2 variant was significantly associated (P<0.05) with decreased SCC, while the presence of A4 was significantly associated with decreased milk yield (P<0.01), increased non-fat solid content (P<0.05), decreased fat content (P<0.01), increased lactose content (P<0.05), and increased pH (P<0.05). In the second region, FABP4 genotype had an effect (P<0.05) on protein content and the presence of the C2 variant was associated (P<0.05) with increased protein content, decreased SCC, and lower pH. The results suggest an association between variation in ovine FABP4 and milk production traits in Greek Sfakia sheep. Nevertheless, further analyses in independent sheep populations of increased size will strengthen these findings.</jats:p> |
| container_issue |
2 |
| container_start_page |
413 |
| container_title |
Archives Animal Breeding |
| container_volume |
62 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792340927432359943 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T16:11:48.376Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Identification+of+the+association+between+%26lt%3Bi%26gt%3BFABP4%26lt%3B%2Fi%26gt%3B+gene+polymorphisms+and+milk+production+traits+in+Sfakia+sheep&rft.date=2019-07-15&genre=article&issn=2363-9822&volume=62&issue=2&spage=413&epage=422&pages=413-422&jtitle=Archives+Animal+Breeding&atitle=Identification+of+the+association+between+%26lt%3Bi%26gt%3BFABP4%26lt%3B%2Fi%26gt%3B+gene+polymorphisms+and+milk+production+traits+in+Sfakia+sheep&aulast=Hickford&aufirst=Jonathan+G.+H.&rft_id=info%3Adoi%2F10.5194%2Faab-62-413-2019&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792340927432359943 |
| author | Ibrahim, Adel H. M., Tzanidakis, Nikolaos, Sotiraki, Smaragda, Zhou, Huitong, Hickford, Jonathan G. H. |
| author_facet | Ibrahim, Adel H. M., Tzanidakis, Nikolaos, Sotiraki, Smaragda, Zhou, Huitong, Hickford, Jonathan G. H., Ibrahim, Adel H. M., Tzanidakis, Nikolaos, Sotiraki, Smaragda, Zhou, Huitong, Hickford, Jonathan G. H. |
| author_sort | ibrahim, adel h. m. |
| container_issue | 2 |
| container_start_page | 413 |
| container_title | Archives Animal Breeding |
| container_volume | 62 |
| description | <jats:p>Abstract. The aim of this study was to estimate the effect of variation in the fatty acid binding protein 4 gene (FABP4) on milk production traits in Greek Sfakia sheep. Polymerase chain reaction – single-stranded conformational polymorphism (PCR-SSCP) analysis was used to genotype a total of 374 Sfakia ewes for two regions of FABP4 located around exon 2–intron 2 (Region 1) and exon 3–intron 3 (Region 2). Each month, for a period of 6 months, milk samples were collected from the ewes to measure total milk yield, fat content, protein content, lactose content, non-fat solid content, pH, and somatic cell count (SCC). A general linear model was used to test the association between the variation observed in FABP4 and milk production traits. Four gene variants (A1–A4) were found in Region 1 and two variants (C1–C2) were found in Region 2. In the first region, the FABP4 genotype significantly affected (P<0.05) non-fat solid levels, fat content, and SCC. The presence of the A2 variant was significantly associated (P<0.05) with decreased SCC, while the presence of A4 was significantly associated with decreased milk yield (P<0.01), increased non-fat solid content (P<0.05), decreased fat content (P<0.01), increased lactose content (P<0.05), and increased pH (P<0.05). In the second region, FABP4 genotype had an effect (P<0.05) on protein content and the presence of the C2 variant was associated (P<0.05) with increased protein content, decreased SCC, and lower pH. The results suggest an association between variation in ovine FABP4 and milk production traits in Greek Sfakia sheep. Nevertheless, further analyses in independent sheep populations of increased size will strengthen these findings.</jats:p> |
| doi_str_mv | 10.5194/aab-62-413-2019 |
| facet_avail | Online, Free |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuNTE5NC9hYWItNjItNDEzLTIwMTk |
| imprint | Copernicus GmbH, 2019 |
| imprint_str_mv | Copernicus GmbH, 2019 |
| institution | DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1 |
| issn | 2363-9822 |
| issn_str_mv | 2363-9822 |
| language | English |
| last_indexed | 2024-03-01T16:11:48.376Z |
| match_str | ibrahim2019identificationoftheassociationbetweenltigtfabp4ltigtgenepolymorphismsandmilkproductiontraitsinsfakiasheep |
| mega_collection | Copernicus GmbH (CrossRef) |
| physical | 413-422 |
| publishDate | 2019 |
| publishDateSort | 2019 |
| publisher | Copernicus GmbH |
| record_format | ai |
| recordtype | ai |
| series | Archives Animal Breeding |
| source_id | 49 |
| spelling | Ibrahim, Adel H. M. Tzanidakis, Nikolaos Sotiraki, Smaragda Zhou, Huitong Hickford, Jonathan G. H. 2363-9822 Copernicus GmbH http://dx.doi.org/10.5194/aab-62-413-2019 <jats:p>Abstract. The aim of this study was to estimate the effect of variation in the fatty acid binding protein 4 gene (FABP4) on milk production traits in Greek Sfakia sheep. Polymerase chain reaction – single-stranded conformational polymorphism (PCR-SSCP) analysis was used to genotype a total of 374 Sfakia ewes for two regions of FABP4 located around exon 2–intron 2 (Region 1) and exon 3–intron 3 (Region 2). Each month, for a period of 6 months, milk samples were collected from the ewes to measure total milk yield, fat content, protein content, lactose content, non-fat solid content, pH, and somatic cell count (SCC). A general linear model was used to test the association between the variation observed in FABP4 and milk production traits. Four gene variants (A1–A4) were found in Region 1 and two variants (C1–C2) were found in Region 2. In the first region, the FABP4 genotype significantly affected (P<0.05) non-fat solid levels, fat content, and SCC. The presence of the A2 variant was significantly associated (P<0.05) with decreased SCC, while the presence of A4 was significantly associated with decreased milk yield (P<0.01), increased non-fat solid content (P<0.05), decreased fat content (P<0.01), increased lactose content (P<0.05), and increased pH (P<0.05). In the second region, FABP4 genotype had an effect (P<0.05) on protein content and the presence of the C2 variant was associated (P<0.05) with increased protein content, decreased SCC, and lower pH. The results suggest an association between variation in ovine FABP4 and milk production traits in Greek Sfakia sheep. Nevertheless, further analyses in independent sheep populations of increased size will strengthen these findings.</jats:p> Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep Archives Animal Breeding |
| spellingShingle | Ibrahim, Adel H. M., Tzanidakis, Nikolaos, Sotiraki, Smaragda, Zhou, Huitong, Hickford, Jonathan G. H., Archives Animal Breeding, Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title | Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title_full | Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title_fullStr | Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title_full_unstemmed | Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title_short | Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| title_sort | identification of the association between <i>fabp4</i> gene polymorphisms and milk production traits in sfakia sheep |
| title_unstemmed | Identification of the association between <i>FABP4</i> gene polymorphisms and milk production traits in Sfakia sheep |
| url | http://dx.doi.org/10.5194/aab-62-413-2019 |