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Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs
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| Zeitschriftentitel: | Gene Expression |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Gene Expression, 16, 2014, 2, S. 85-92 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Xia & He Publishing
|
| Schlagwörter: |
| author_facet |
Reyes, Ryan K. Motiwala, Tasneem Jacob, Samson T. Reyes, Ryan K. Motiwala, Tasneem Jacob, Samson T. |
|---|---|
| author |
Reyes, Ryan K. Motiwala, Tasneem Jacob, Samson T. |
| spellingShingle |
Reyes, Ryan K. Motiwala, Tasneem Jacob, Samson T. Gene Expression Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs Genetics Molecular Biology |
| author_sort |
reyes, ryan k. |
| spelling |
Reyes, Ryan K. Motiwala, Tasneem Jacob, Samson T. 1052-2166 Xia & He Publishing Genetics Molecular Biology http://dx.doi.org/10.3727/105221614x13919976902093 <jats:p>In the past decade, considerable effort has been made in elucidating the mechanism underlying the high level of aerobic glycolysis in cancer cells. While some recent studies have attempted to address this issue, the potential role of microRNAs in this process has not been explored until recently. These studies have demonstrated involvement of just five deregulated miRNAs in glucose metabolism in hepatocarcinogenesis. This review discusses the metabolic significance of these miRNAs in hepatoceullular carcinoma, their targets in glycolysis, gluconeogenesis, and pentose phosphate pathways, and provides an insight into the therapeutic potential of targeting specific miRNAs.</jats:p> Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs Gene Expression |
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Gene Expression |
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49 |
| title |
Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| title_unstemmed |
Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| title_full |
Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| title_fullStr |
Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| title_full_unstemmed |
Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| title_short |
Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| title_sort |
regulation of glucose metabolism in hepatocarcinogenesis by micrornas |
| topic |
Genetics Molecular Biology |
| url |
http://dx.doi.org/10.3727/105221614x13919976902093 |
| publishDate |
2014 |
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85-92 |
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<jats:p>In the past decade, considerable effort has been made in elucidating the mechanism underlying the high level of aerobic glycolysis in cancer cells. While some recent studies have attempted to address this issue, the potential role of microRNAs in this process has not been explored until
recently. These studies have demonstrated involvement of just five deregulated miRNAs in glucose metabolism in hepatocarcinogenesis. This review discusses the metabolic significance of these miRNAs in hepatoceullular carcinoma, their targets in glycolysis, gluconeogenesis, and pentose phosphate
pathways, and provides an insight into the therapeutic potential of targeting specific miRNAs.</jats:p> |
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| author | Reyes, Ryan K., Motiwala, Tasneem, Jacob, Samson T. |
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| description | <jats:p>In the past decade, considerable effort has been made in elucidating the mechanism underlying the high level of aerobic glycolysis in cancer cells. While some recent studies have attempted to address this issue, the potential role of microRNAs in this process has not been explored until recently. These studies have demonstrated involvement of just five deregulated miRNAs in glucose metabolism in hepatocarcinogenesis. This review discusses the metabolic significance of these miRNAs in hepatoceullular carcinoma, their targets in glycolysis, gluconeogenesis, and pentose phosphate pathways, and provides an insight into the therapeutic potential of targeting specific miRNAs.</jats:p> |
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| imprint | Xia & He Publishing, 2014 |
| imprint_str_mv | Xia & He Publishing, 2014 |
| institution | DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1 |
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| physical | 85-92 |
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| publisher | Xia & He Publishing |
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| recordtype | ai |
| series | Gene Expression |
| source_id | 49 |
| spelling | Reyes, Ryan K. Motiwala, Tasneem Jacob, Samson T. 1052-2166 Xia & He Publishing Genetics Molecular Biology http://dx.doi.org/10.3727/105221614x13919976902093 <jats:p>In the past decade, considerable effort has been made in elucidating the mechanism underlying the high level of aerobic glycolysis in cancer cells. While some recent studies have attempted to address this issue, the potential role of microRNAs in this process has not been explored until recently. These studies have demonstrated involvement of just five deregulated miRNAs in glucose metabolism in hepatocarcinogenesis. This review discusses the metabolic significance of these miRNAs in hepatoceullular carcinoma, their targets in glycolysis, gluconeogenesis, and pentose phosphate pathways, and provides an insight into the therapeutic potential of targeting specific miRNAs.</jats:p> Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs Gene Expression |
| spellingShingle | Reyes, Ryan K., Motiwala, Tasneem, Jacob, Samson T., Gene Expression, Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs, Genetics, Molecular Biology |
| title | Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| title_full | Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| title_fullStr | Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| title_full_unstemmed | Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| title_short | Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| title_sort | regulation of glucose metabolism in hepatocarcinogenesis by micrornas |
| title_unstemmed | Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs |
| topic | Genetics, Molecular Biology |
| url | http://dx.doi.org/10.3727/105221614x13919976902093 |