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Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease
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| Zeitschriftentitel: | Nutrients |
|---|---|
| Personen und Körperschaften: | , , , , , , |
| In: | Nutrients, 11, 2019, 1, S. 86 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
MDPI AG
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| Schlagwörter: |
| author_facet |
Rico, Daniel Martin-Diana, Ana Belén Lasa, Arrate Aguirre, Leixuri Milton-Laskibar, Iñaki De Luis, Daniel Antonio Miranda, Jonatan Rico, Daniel Martin-Diana, Ana Belén Lasa, Arrate Aguirre, Leixuri Milton-Laskibar, Iñaki De Luis, Daniel Antonio Miranda, Jonatan |
|---|---|
| author |
Rico, Daniel Martin-Diana, Ana Belén Lasa, Arrate Aguirre, Leixuri Milton-Laskibar, Iñaki De Luis, Daniel Antonio Miranda, Jonatan |
| spellingShingle |
Rico, Daniel Martin-Diana, Ana Belén Lasa, Arrate Aguirre, Leixuri Milton-Laskibar, Iñaki De Luis, Daniel Antonio Miranda, Jonatan Nutrients Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease Food Science Nutrition and Dietetics |
| author_sort |
rico, daniel |
| spelling |
Rico, Daniel Martin-Diana, Ana Belén Lasa, Arrate Aguirre, Leixuri Milton-Laskibar, Iñaki De Luis, Daniel Antonio Miranda, Jonatan 2072-6643 MDPI AG Food Science Nutrition and Dietetics http://dx.doi.org/10.3390/nu11010086 <jats:p>Snacks combining different functional ingredients could represent a useful therapeutic strategy against NAFLD. The present study aimed to analyze the effect of two snack formulations based on carob and wakame flour in the treatment for NAFLD in rats. For this purpose, metabolic syndrome was induced in 50 adult rats by a high-fat high-fructose diet over eight weeks. After this period, rats were fed either normal calorie diets supplemented or not with snack A (1/50 wakame/carob pod) and snack B (1/5 wakame/carob pod) for four additional weeks. After sacrifice, liver composition and serum parameters were analyzed. Different pathways of triacylglycerol metabolism in liver were studied including fatty acid oxidation, fatty acid synthesis, triglyceride assembly and release, fatty acid uptake and glucose uptake. Oxidative stress was also measured. Snack treatment, and mainly B snack, reduced liver triacylglycerol levels by increasing fat oxidation. Moreover, this snack reduced oxidative stress. Therefore, this snack formulation could represent an interesting tool useful for fatty liver treatment.</jats:p> Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease Nutrients |
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| title |
Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| title_unstemmed |
Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| title_full |
Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| title_fullStr |
Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| title_full_unstemmed |
Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| title_short |
Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| title_sort |
effect of wakame and carob pod snacks on non-alcoholic fatty liver disease |
| topic |
Food Science Nutrition and Dietetics |
| url |
http://dx.doi.org/10.3390/nu11010086 |
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2019 |
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86 |
| description |
<jats:p>Snacks combining different functional ingredients could represent a useful therapeutic strategy against NAFLD. The present study aimed to analyze the effect of two snack formulations based on carob and wakame flour in the treatment for NAFLD in rats. For this purpose, metabolic syndrome was induced in 50 adult rats by a high-fat high-fructose diet over eight weeks. After this period, rats were fed either normal calorie diets supplemented or not with snack A (1/50 wakame/carob pod) and snack B (1/5 wakame/carob pod) for four additional weeks. After sacrifice, liver composition and serum parameters were analyzed. Different pathways of triacylglycerol metabolism in liver were studied including fatty acid oxidation, fatty acid synthesis, triglyceride assembly and release, fatty acid uptake and glucose uptake. Oxidative stress was also measured. Snack treatment, and mainly B snack, reduced liver triacylglycerol levels by increasing fat oxidation. Moreover, this snack reduced oxidative stress. Therefore, this snack formulation could represent an interesting tool useful for fatty liver treatment.</jats:p> |
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| author | Rico, Daniel, Martin-Diana, Ana Belén, Lasa, Arrate, Aguirre, Leixuri, Milton-Laskibar, Iñaki, De Luis, Daniel Antonio, Miranda, Jonatan |
| author_facet | Rico, Daniel, Martin-Diana, Ana Belén, Lasa, Arrate, Aguirre, Leixuri, Milton-Laskibar, Iñaki, De Luis, Daniel Antonio, Miranda, Jonatan, Rico, Daniel, Martin-Diana, Ana Belén, Lasa, Arrate, Aguirre, Leixuri, Milton-Laskibar, Iñaki, De Luis, Daniel Antonio, Miranda, Jonatan |
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| description | <jats:p>Snacks combining different functional ingredients could represent a useful therapeutic strategy against NAFLD. The present study aimed to analyze the effect of two snack formulations based on carob and wakame flour in the treatment for NAFLD in rats. For this purpose, metabolic syndrome was induced in 50 adult rats by a high-fat high-fructose diet over eight weeks. After this period, rats were fed either normal calorie diets supplemented or not with snack A (1/50 wakame/carob pod) and snack B (1/5 wakame/carob pod) for four additional weeks. After sacrifice, liver composition and serum parameters were analyzed. Different pathways of triacylglycerol metabolism in liver were studied including fatty acid oxidation, fatty acid synthesis, triglyceride assembly and release, fatty acid uptake and glucose uptake. Oxidative stress was also measured. Snack treatment, and mainly B snack, reduced liver triacylglycerol levels by increasing fat oxidation. Moreover, this snack reduced oxidative stress. Therefore, this snack formulation could represent an interesting tool useful for fatty liver treatment.</jats:p> |
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| spelling | Rico, Daniel Martin-Diana, Ana Belén Lasa, Arrate Aguirre, Leixuri Milton-Laskibar, Iñaki De Luis, Daniel Antonio Miranda, Jonatan 2072-6643 MDPI AG Food Science Nutrition and Dietetics http://dx.doi.org/10.3390/nu11010086 <jats:p>Snacks combining different functional ingredients could represent a useful therapeutic strategy against NAFLD. The present study aimed to analyze the effect of two snack formulations based on carob and wakame flour in the treatment for NAFLD in rats. For this purpose, metabolic syndrome was induced in 50 adult rats by a high-fat high-fructose diet over eight weeks. After this period, rats were fed either normal calorie diets supplemented or not with snack A (1/50 wakame/carob pod) and snack B (1/5 wakame/carob pod) for four additional weeks. After sacrifice, liver composition and serum parameters were analyzed. Different pathways of triacylglycerol metabolism in liver were studied including fatty acid oxidation, fatty acid synthesis, triglyceride assembly and release, fatty acid uptake and glucose uptake. Oxidative stress was also measured. Snack treatment, and mainly B snack, reduced liver triacylglycerol levels by increasing fat oxidation. Moreover, this snack reduced oxidative stress. Therefore, this snack formulation could represent an interesting tool useful for fatty liver treatment.</jats:p> Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease Nutrients |
| spellingShingle | Rico, Daniel, Martin-Diana, Ana Belén, Lasa, Arrate, Aguirre, Leixuri, Milton-Laskibar, Iñaki, De Luis, Daniel Antonio, Miranda, Jonatan, Nutrients, Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease, Food Science, Nutrition and Dietetics |
| title | Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| title_full | Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| title_fullStr | Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| title_full_unstemmed | Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| title_short | Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| title_sort | effect of wakame and carob pod snacks on non-alcoholic fatty liver disease |
| title_unstemmed | Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| topic | Food Science, Nutrition and Dietetics |
| url | http://dx.doi.org/10.3390/nu11010086 |