Eintrag weiter verarbeiten
Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study
Gespeichert in:
| Zeitschriftentitel: | Diagnostics |
|---|---|
| Personen und Körperschaften: | , , , , , , , , |
| In: | Diagnostics, 11, 2021, 2, S. 374 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
MDPI AG
|
| Schlagwörter: |
| author_facet |
Małek, Łukasz A. Mazurkiewicz, Łukasz Marszałek, Mikołaj Barczuk-Falęcka, Marzena Simon, Jenny E. Grzybowski, Jacek Miłosz-Wieczorek, Barbara Postuła, Marek Marczak, Magdalena Małek, Łukasz A. Mazurkiewicz, Łukasz Marszałek, Mikołaj Barczuk-Falęcka, Marzena Simon, Jenny E. Grzybowski, Jacek Miłosz-Wieczorek, Barbara Postuła, Marek Marczak, Magdalena |
|---|---|
| author |
Małek, Łukasz A. Mazurkiewicz, Łukasz Marszałek, Mikołaj Barczuk-Falęcka, Marzena Simon, Jenny E. Grzybowski, Jacek Miłosz-Wieczorek, Barbara Postuła, Marek Marczak, Magdalena |
| spellingShingle |
Małek, Łukasz A. Mazurkiewicz, Łukasz Marszałek, Mikołaj Barczuk-Falęcka, Marzena Simon, Jenny E. Grzybowski, Jacek Miłosz-Wieczorek, Barbara Postuła, Marek Marczak, Magdalena Diagnostics Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study Clinical Biochemistry |
| author_sort |
małek, łukasz a. |
| spelling |
Małek, Łukasz A. Mazurkiewicz, Łukasz Marszałek, Mikołaj Barczuk-Falęcka, Marzena Simon, Jenny E. Grzybowski, Jacek Miłosz-Wieczorek, Barbara Postuła, Marek Marczak, Magdalena 2075-4418 MDPI AG Clinical Biochemistry http://dx.doi.org/10.3390/diagnostics11020374 <jats:p>A better understanding of the left ventricle (LV) and right ventricle (RV) functioning would help with the differentiation between athlete’s heart and dilated cardiomyopathy (DCM). We aimed to analyse deformation parameters in endurance athletes relative to patients with DCM using cardiac magnetic resonance feature tracking (CMR-FT). The study included males of a similar age: 22 ultramarathon runners, 22 patients with DCM and 21 sedentary healthy controls (41 ± 9 years). The analysed parameters were peak LV global longitudinal, circumferential and radial strains (GLS, GCS and GRS, respectively); peak LV torsion; peak RV GLS. The peak LV GLS was similar in controls and athletes, but lower in DCM (p < 0.0001). Peak LV GCS and GRS decreased from controls to DCM (both p < 0.0001). The best value for differentiation between DCM and other groups was found for the LV ejection fraction (area under the curve (AUC) = 0.990, p = 0.0001, with 90.9% sensitivity and 100% specificity for ≤53%) and the peak LV GRS diastolic rate (AUC = 0.987, p = 0.0001, with 100% sensitivity and 88.4% specificity for >−1.27 s−1). The peak LV GRS diastolic rate was the only independent predictor of DCM (p = 0.003). Distinctive deformation patterns that were typical for each of the analysed groups existed and can help to differentiate between athlete’s heart, a nonathletic heart and a dilated cardiomyopathy.</jats:p> Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study Diagnostics |
| doi_str_mv |
10.3390/diagnostics11020374 |
| facet_avail |
Online Free |
| finc_class_facet |
Medizin Biologie Chemie und Pharmazie |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMzM5MC9kaWFnbm9zdGljczExMDIwMzc0 |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMzM5MC9kaWFnbm9zdGljczExMDIwMzc0 |
| institution |
DE-15 DE-Rs1 DE-Pl11 DE-105 DE-14 DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 |
| imprint |
MDPI AG, 2021 |
| imprint_str_mv |
MDPI AG, 2021 |
| issn |
2075-4418 |
| issn_str_mv |
2075-4418 |
| language |
English |
| mega_collection |
MDPI AG (CrossRef) |
| match_str |
malek2021deformationparametersoftheheartinenduranceathletesandinpatientswithdilatedcardiomyopathyacardiacmagneticresonancestudy |
| publishDateSort |
2021 |
| publisher |
MDPI AG |
| recordtype |
ai |
| record_format |
ai |
| series |
Diagnostics |
| source_id |
49 |
| title |
Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| title_unstemmed |
Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| title_full |
Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| title_fullStr |
Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| title_full_unstemmed |
Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| title_short |
Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| title_sort |
deformation parameters of the heart in endurance athletes and in patients with dilated cardiomyopathy—a cardiac magnetic resonance study |
| topic |
Clinical Biochemistry |
| url |
http://dx.doi.org/10.3390/diagnostics11020374 |
| publishDate |
2021 |
| physical |
374 |
| description |
<jats:p>A better understanding of the left ventricle (LV) and right ventricle (RV) functioning would help with the differentiation between athlete’s heart and dilated cardiomyopathy (DCM). We aimed to analyse deformation parameters in endurance athletes relative to patients with DCM using cardiac magnetic resonance feature tracking (CMR-FT). The study included males of a similar age: 22 ultramarathon runners, 22 patients with DCM and 21 sedentary healthy controls (41 ± 9 years). The analysed parameters were peak LV global longitudinal, circumferential and radial strains (GLS, GCS and GRS, respectively); peak LV torsion; peak RV GLS. The peak LV GLS was similar in controls and athletes, but lower in DCM (p < 0.0001). Peak LV GCS and GRS decreased from controls to DCM (both p < 0.0001). The best value for differentiation between DCM and other groups was found for the LV ejection fraction (area under the curve (AUC) = 0.990, p = 0.0001, with 90.9% sensitivity and 100% specificity for ≤53%) and the peak LV GRS diastolic rate (AUC = 0.987, p = 0.0001, with 100% sensitivity and 88.4% specificity for >−1.27 s−1). The peak LV GRS diastolic rate was the only independent predictor of DCM (p = 0.003). Distinctive deformation patterns that were typical for each of the analysed groups existed and can help to differentiate between athlete’s heart, a nonathletic heart and a dilated cardiomyopathy.</jats:p> |
| container_issue |
2 |
| container_start_page |
0 |
| container_title |
Diagnostics |
| container_volume |
11 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792348312755503114 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T18:09:11.791Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Deformation+Parameters+of+the+Heart+in+Endurance+Athletes+and+in+Patients+with+Dilated+Cardiomyopathy%E2%80%94A+Cardiac+Magnetic+Resonance+Study&rft.date=2021-02-22&genre=article&issn=2075-4418&volume=11&issue=2&pages=374&jtitle=Diagnostics&atitle=Deformation+Parameters+of+the+Heart+in+Endurance+Athletes+and+in+Patients+with+Dilated+Cardiomyopathy%E2%80%94A+Cardiac+Magnetic+Resonance+Study&aulast=Marczak&aufirst=Magdalena&rft_id=info%3Adoi%2F10.3390%2Fdiagnostics11020374&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792348312755503114 |
| author | Małek, Łukasz A., Mazurkiewicz, Łukasz, Marszałek, Mikołaj, Barczuk-Falęcka, Marzena, Simon, Jenny E., Grzybowski, Jacek, Miłosz-Wieczorek, Barbara, Postuła, Marek, Marczak, Magdalena |
| author_facet | Małek, Łukasz A., Mazurkiewicz, Łukasz, Marszałek, Mikołaj, Barczuk-Falęcka, Marzena, Simon, Jenny E., Grzybowski, Jacek, Miłosz-Wieczorek, Barbara, Postuła, Marek, Marczak, Magdalena, Małek, Łukasz A., Mazurkiewicz, Łukasz, Marszałek, Mikołaj, Barczuk-Falęcka, Marzena, Simon, Jenny E., Grzybowski, Jacek, Miłosz-Wieczorek, Barbara, Postuła, Marek, Marczak, Magdalena |
| author_sort | małek, łukasz a. |
| container_issue | 2 |
| container_start_page | 0 |
| container_title | Diagnostics |
| container_volume | 11 |
| description | <jats:p>A better understanding of the left ventricle (LV) and right ventricle (RV) functioning would help with the differentiation between athlete’s heart and dilated cardiomyopathy (DCM). We aimed to analyse deformation parameters in endurance athletes relative to patients with DCM using cardiac magnetic resonance feature tracking (CMR-FT). The study included males of a similar age: 22 ultramarathon runners, 22 patients with DCM and 21 sedentary healthy controls (41 ± 9 years). The analysed parameters were peak LV global longitudinal, circumferential and radial strains (GLS, GCS and GRS, respectively); peak LV torsion; peak RV GLS. The peak LV GLS was similar in controls and athletes, but lower in DCM (p < 0.0001). Peak LV GCS and GRS decreased from controls to DCM (both p < 0.0001). The best value for differentiation between DCM and other groups was found for the LV ejection fraction (area under the curve (AUC) = 0.990, p = 0.0001, with 90.9% sensitivity and 100% specificity for ≤53%) and the peak LV GRS diastolic rate (AUC = 0.987, p = 0.0001, with 100% sensitivity and 88.4% specificity for >−1.27 s−1). The peak LV GRS diastolic rate was the only independent predictor of DCM (p = 0.003). Distinctive deformation patterns that were typical for each of the analysed groups existed and can help to differentiate between athlete’s heart, a nonathletic heart and a dilated cardiomyopathy.</jats:p> |
| doi_str_mv | 10.3390/diagnostics11020374 |
| facet_avail | Online, Free |
| finc_class_facet | Medizin, Biologie, Chemie und Pharmazie |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMzM5MC9kaWFnbm9zdGljczExMDIwMzc0 |
| imprint | MDPI AG, 2021 |
| imprint_str_mv | MDPI AG, 2021 |
| institution | DE-15, DE-Rs1, DE-Pl11, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4 |
| issn | 2075-4418 |
| issn_str_mv | 2075-4418 |
| language | English |
| last_indexed | 2024-03-01T18:09:11.791Z |
| match_str | malek2021deformationparametersoftheheartinenduranceathletesandinpatientswithdilatedcardiomyopathyacardiacmagneticresonancestudy |
| mega_collection | MDPI AG (CrossRef) |
| physical | 374 |
| publishDate | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI AG |
| record_format | ai |
| recordtype | ai |
| series | Diagnostics |
| source_id | 49 |
| spelling | Małek, Łukasz A. Mazurkiewicz, Łukasz Marszałek, Mikołaj Barczuk-Falęcka, Marzena Simon, Jenny E. Grzybowski, Jacek Miłosz-Wieczorek, Barbara Postuła, Marek Marczak, Magdalena 2075-4418 MDPI AG Clinical Biochemistry http://dx.doi.org/10.3390/diagnostics11020374 <jats:p>A better understanding of the left ventricle (LV) and right ventricle (RV) functioning would help with the differentiation between athlete’s heart and dilated cardiomyopathy (DCM). We aimed to analyse deformation parameters in endurance athletes relative to patients with DCM using cardiac magnetic resonance feature tracking (CMR-FT). The study included males of a similar age: 22 ultramarathon runners, 22 patients with DCM and 21 sedentary healthy controls (41 ± 9 years). The analysed parameters were peak LV global longitudinal, circumferential and radial strains (GLS, GCS and GRS, respectively); peak LV torsion; peak RV GLS. The peak LV GLS was similar in controls and athletes, but lower in DCM (p < 0.0001). Peak LV GCS and GRS decreased from controls to DCM (both p < 0.0001). The best value for differentiation between DCM and other groups was found for the LV ejection fraction (area under the curve (AUC) = 0.990, p = 0.0001, with 90.9% sensitivity and 100% specificity for ≤53%) and the peak LV GRS diastolic rate (AUC = 0.987, p = 0.0001, with 100% sensitivity and 88.4% specificity for >−1.27 s−1). The peak LV GRS diastolic rate was the only independent predictor of DCM (p = 0.003). Distinctive deformation patterns that were typical for each of the analysed groups existed and can help to differentiate between athlete’s heart, a nonathletic heart and a dilated cardiomyopathy.</jats:p> Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study Diagnostics |
| spellingShingle | Małek, Łukasz A., Mazurkiewicz, Łukasz, Marszałek, Mikołaj, Barczuk-Falęcka, Marzena, Simon, Jenny E., Grzybowski, Jacek, Miłosz-Wieczorek, Barbara, Postuła, Marek, Marczak, Magdalena, Diagnostics, Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study, Clinical Biochemistry |
| title | Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| title_full | Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| title_fullStr | Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| title_full_unstemmed | Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| title_short | Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| title_sort | deformation parameters of the heart in endurance athletes and in patients with dilated cardiomyopathy—a cardiac magnetic resonance study |
| title_unstemmed | Deformation Parameters of the Heart in Endurance Athletes and in Patients with Dilated Cardiomyopathy—A Cardiac Magnetic Resonance Study |
| topic | Clinical Biochemistry |
| url | http://dx.doi.org/10.3390/diagnostics11020374 |