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Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review
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| Zeitschriftentitel: | Cancers |
|---|---|
| Personen und Körperschaften: | , , , , , , , , |
| In: | Cancers, 12, 2020, 3, S. 733 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
MDPI AG
|
| Schlagwörter: |
| author_facet |
Özdirik, Burcin Kayser, Antonin Ullrich, Andrea Savic, Lynn J. Reiss, Markus Tacke, Frank Wiedenmann, Bertram Jann, Henning Roderburg, Christoph Özdirik, Burcin Kayser, Antonin Ullrich, Andrea Savic, Lynn J. Reiss, Markus Tacke, Frank Wiedenmann, Bertram Jann, Henning Roderburg, Christoph |
|---|---|
| author |
Özdirik, Burcin Kayser, Antonin Ullrich, Andrea Savic, Lynn J. Reiss, Markus Tacke, Frank Wiedenmann, Bertram Jann, Henning Roderburg, Christoph |
| spellingShingle |
Özdirik, Burcin Kayser, Antonin Ullrich, Andrea Savic, Lynn J. Reiss, Markus Tacke, Frank Wiedenmann, Bertram Jann, Henning Roderburg, Christoph Cancers Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review Cancer Research Oncology |
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özdirik, burcin |
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Özdirik, Burcin Kayser, Antonin Ullrich, Andrea Savic, Lynn J. Reiss, Markus Tacke, Frank Wiedenmann, Bertram Jann, Henning Roderburg, Christoph 2072-6694 MDPI AG Cancer Research Oncology http://dx.doi.org/10.3390/cancers12030733 <jats:p>Primary neuroendocrine carcinoma of the breast (NECB) as defined by the World Health Organization (WHO) in 2012 is a rare, but possibly under-diagnosed entity. It is heterogeneous as it entails a wide spectrum of diseases comprising both well-differentiated neuroendocrine tumors of the breast as well as highly aggressive small cell carcinomas. Retrospective screening of hospital charts of 612 patients (2008–2019) from our specialized outpatient unit for neuroendocrine neoplasia revealed five patients diagnosed with NECB. Given the low prevalence of these malignancies, correct diagnosis remains a challenge that requires an interdisciplinary approach. Specifically, NECB may be misclassified as carcinoma of the breast with neuroendocrine differentiation, carcinomas of the breast of no special type/invasive ductal carcinoma, or a metastasis to the breast. Therefore, this study presents multifaceted characteristics as well as the clinical course of these patients and discusses the five cases from our institution in the context of available literature.</jats:p> Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review Cancers |
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MDPI AG, 2020 |
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| title |
Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| title_unstemmed |
Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| title_full |
Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| title_fullStr |
Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| title_full_unstemmed |
Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| title_short |
Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| title_sort |
primary neuroendocrine neoplasms of the breast: case series and literature review |
| topic |
Cancer Research Oncology |
| url |
http://dx.doi.org/10.3390/cancers12030733 |
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2020 |
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733 |
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<jats:p>Primary neuroendocrine carcinoma of the breast (NECB) as defined by the World Health Organization (WHO) in 2012 is a rare, but possibly under-diagnosed entity. It is heterogeneous as it entails a wide spectrum of diseases comprising both well-differentiated neuroendocrine tumors of the breast as well as highly aggressive small cell carcinomas. Retrospective screening of hospital charts of 612 patients (2008–2019) from our specialized outpatient unit for neuroendocrine neoplasia revealed five patients diagnosed with NECB. Given the low prevalence of these malignancies, correct diagnosis remains a challenge that requires an interdisciplinary approach. Specifically, NECB may be misclassified as carcinoma of the breast with neuroendocrine differentiation, carcinomas of the breast of no special type/invasive ductal carcinoma, or a metastasis to the breast. Therefore, this study presents multifaceted characteristics as well as the clinical course of these patients and discusses the five cases from our institution in the context of available literature.</jats:p> |
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| author | Özdirik, Burcin, Kayser, Antonin, Ullrich, Andrea, Savic, Lynn J., Reiss, Markus, Tacke, Frank, Wiedenmann, Bertram, Jann, Henning, Roderburg, Christoph |
| author_facet | Özdirik, Burcin, Kayser, Antonin, Ullrich, Andrea, Savic, Lynn J., Reiss, Markus, Tacke, Frank, Wiedenmann, Bertram, Jann, Henning, Roderburg, Christoph, Özdirik, Burcin, Kayser, Antonin, Ullrich, Andrea, Savic, Lynn J., Reiss, Markus, Tacke, Frank, Wiedenmann, Bertram, Jann, Henning, Roderburg, Christoph |
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| description | <jats:p>Primary neuroendocrine carcinoma of the breast (NECB) as defined by the World Health Organization (WHO) in 2012 is a rare, but possibly under-diagnosed entity. It is heterogeneous as it entails a wide spectrum of diseases comprising both well-differentiated neuroendocrine tumors of the breast as well as highly aggressive small cell carcinomas. Retrospective screening of hospital charts of 612 patients (2008–2019) from our specialized outpatient unit for neuroendocrine neoplasia revealed five patients diagnosed with NECB. Given the low prevalence of these malignancies, correct diagnosis remains a challenge that requires an interdisciplinary approach. Specifically, NECB may be misclassified as carcinoma of the breast with neuroendocrine differentiation, carcinomas of the breast of no special type/invasive ductal carcinoma, or a metastasis to the breast. Therefore, this study presents multifaceted characteristics as well as the clinical course of these patients and discusses the five cases from our institution in the context of available literature.</jats:p> |
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| spelling | Özdirik, Burcin Kayser, Antonin Ullrich, Andrea Savic, Lynn J. Reiss, Markus Tacke, Frank Wiedenmann, Bertram Jann, Henning Roderburg, Christoph 2072-6694 MDPI AG Cancer Research Oncology http://dx.doi.org/10.3390/cancers12030733 <jats:p>Primary neuroendocrine carcinoma of the breast (NECB) as defined by the World Health Organization (WHO) in 2012 is a rare, but possibly under-diagnosed entity. It is heterogeneous as it entails a wide spectrum of diseases comprising both well-differentiated neuroendocrine tumors of the breast as well as highly aggressive small cell carcinomas. Retrospective screening of hospital charts of 612 patients (2008–2019) from our specialized outpatient unit for neuroendocrine neoplasia revealed five patients diagnosed with NECB. Given the low prevalence of these malignancies, correct diagnosis remains a challenge that requires an interdisciplinary approach. Specifically, NECB may be misclassified as carcinoma of the breast with neuroendocrine differentiation, carcinomas of the breast of no special type/invasive ductal carcinoma, or a metastasis to the breast. Therefore, this study presents multifaceted characteristics as well as the clinical course of these patients and discusses the five cases from our institution in the context of available literature.</jats:p> Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review Cancers |
| spellingShingle | Özdirik, Burcin, Kayser, Antonin, Ullrich, Andrea, Savic, Lynn J., Reiss, Markus, Tacke, Frank, Wiedenmann, Bertram, Jann, Henning, Roderburg, Christoph, Cancers, Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review, Cancer Research, Oncology |
| title | Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| title_full | Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| title_fullStr | Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| title_full_unstemmed | Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| title_short | Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| title_sort | primary neuroendocrine neoplasms of the breast: case series and literature review |
| title_unstemmed | Primary Neuroendocrine Neoplasms of the Breast: Case Series and Literature Review |
| topic | Cancer Research, Oncology |
| url | http://dx.doi.org/10.3390/cancers12030733 |