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An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens
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| Zeitschriftentitel: | Antibiotics |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , |
| In: | Antibiotics, 8, 2019, 4, S. 213 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
MDPI AG
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| Schlagwörter: |
| author_facet |
Karetsi, V.A. Banti, C.N. Kourkoumelis, N. Papachristodoulou, C. Stalikas, C.D. Raptopoulou, C.P. Psycharis, V. Zoumpoulakis, P. Mavromoustakos, T. Sainis, I. Hadjikakou, S.K. Karetsi, V.A. Banti, C.N. Kourkoumelis, N. Papachristodoulou, C. Stalikas, C.D. Raptopoulou, C.P. Psycharis, V. Zoumpoulakis, P. Mavromoustakos, T. Sainis, I. Hadjikakou, S.K. |
|---|---|
| author |
Karetsi, V.A. Banti, C.N. Kourkoumelis, N. Papachristodoulou, C. Stalikas, C.D. Raptopoulou, C.P. Psycharis, V. Zoumpoulakis, P. Mavromoustakos, T. Sainis, I. Hadjikakou, S.K. |
| spellingShingle |
Karetsi, V.A. Banti, C.N. Kourkoumelis, N. Papachristodoulou, C. Stalikas, C.D. Raptopoulou, C.P. Psycharis, V. Zoumpoulakis, P. Mavromoustakos, T. Sainis, I. Hadjikakou, S.K. Antibiotics An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens Pharmacology (medical) Infectious Diseases Microbiology (medical) General Pharmacology, Toxicology and Pharmaceutics Biochemistry Microbiology |
| author_sort |
karetsi, v.a. |
| spelling |
Karetsi, V.A. Banti, C.N. Kourkoumelis, N. Papachristodoulou, C. Stalikas, C.D. Raptopoulou, C.P. Psycharis, V. Zoumpoulakis, P. Mavromoustakos, T. Sainis, I. Hadjikakou, S.K. 2079-6382 MDPI AG Pharmacology (medical) Infectious Diseases Microbiology (medical) General Pharmacology, Toxicology and Pharmaceutics Biochemistry Microbiology http://dx.doi.org/10.3390/antibiotics8040213 <jats:p>The [Zn3(CitH)2] (1) (CitH4= citric acid), was dispersed in sodium lauryl sulphate (SLS) to form the micelle of SLS@[Zn3(CitH)2] (2). This material 2 was incorporated in hydrogel made by hydroxyethyl-methacrylate (HEMA), an ingredient of contact lenses, toward the formation of pHEMA@(SLS@[Zn3(CitH)2]) (3). Samples of 1 and 2 were characterized by UV-Vis, 1H-NMR, FT-IR, FT-Raman, single crystal X-ray crystallography, X-ray fluorescence analysis, atomic absorption and TG/DTA/DSC. The antibacterial activity of 1–3 as well as of SLS against Gram-positive (Staphylococcus epidermidis (St. epidermidis) and Staphylococcus aureus (St. aureus)) and Gram-negative (Pseudomonas aeruginosa (PAO1), and Escherichia coli (E. coli)) bacteria was evaluated by the means of minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and inhibitory zone (IZ). 2 showed 10 to 20-fold higher activity than 1 against the bacteria tested. Moreover the 3 decreases the abundance of Gram-positive microbes up to 30% (St. aureus) and up to 20% (PAO1) the Gram-negative ones. The noteworthy antimicrobial activity of the obtained composite 3 suggests an effective antimicrobial additive for infection-free contact lenses.</jats:p> An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens Antibiotics |
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10.3390/antibiotics8040213 |
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| title |
An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| title_unstemmed |
An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| title_full |
An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| title_fullStr |
An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| title_full_unstemmed |
An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| title_short |
An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| title_sort |
an efficient disinfectant, composite material {sls@[zn3(cith)2]} as ingredient for development of sterilized and non infectious contact lens |
| topic |
Pharmacology (medical) Infectious Diseases Microbiology (medical) General Pharmacology, Toxicology and Pharmaceutics Biochemistry Microbiology |
| url |
http://dx.doi.org/10.3390/antibiotics8040213 |
| publishDate |
2019 |
| physical |
213 |
| description |
<jats:p>The [Zn3(CitH)2] (1) (CitH4= citric acid), was dispersed in sodium lauryl sulphate (SLS) to form the micelle of SLS@[Zn3(CitH)2] (2). This material 2 was incorporated in hydrogel made by hydroxyethyl-methacrylate (HEMA), an ingredient of contact lenses, toward the formation of pHEMA@(SLS@[Zn3(CitH)2]) (3). Samples of 1 and 2 were characterized by UV-Vis, 1H-NMR, FT-IR, FT-Raman, single crystal X-ray crystallography, X-ray fluorescence analysis, atomic absorption and TG/DTA/DSC. The antibacterial activity of 1–3 as well as of SLS against Gram-positive (Staphylococcus epidermidis (St. epidermidis) and Staphylococcus aureus (St. aureus)) and Gram-negative (Pseudomonas aeruginosa (PAO1), and Escherichia coli (E. coli)) bacteria was evaluated by the means of minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and inhibitory zone (IZ). 2 showed 10 to 20-fold higher activity than 1 against the bacteria tested. Moreover the 3 decreases the abundance of Gram-positive microbes up to 30% (St. aureus) and up to 20% (PAO1) the Gram-negative ones. The noteworthy antimicrobial activity of the obtained composite 3 suggests an effective antimicrobial additive for infection-free contact lenses.</jats:p> |
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| author | Karetsi, V.A., Banti, C.N., Kourkoumelis, N., Papachristodoulou, C., Stalikas, C.D., Raptopoulou, C.P., Psycharis, V., Zoumpoulakis, P., Mavromoustakos, T., Sainis, I., Hadjikakou, S.K. |
| author_facet | Karetsi, V.A., Banti, C.N., Kourkoumelis, N., Papachristodoulou, C., Stalikas, C.D., Raptopoulou, C.P., Psycharis, V., Zoumpoulakis, P., Mavromoustakos, T., Sainis, I., Hadjikakou, S.K., Karetsi, V.A., Banti, C.N., Kourkoumelis, N., Papachristodoulou, C., Stalikas, C.D., Raptopoulou, C.P., Psycharis, V., Zoumpoulakis, P., Mavromoustakos, T., Sainis, I., Hadjikakou, S.K. |
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| description | <jats:p>The [Zn3(CitH)2] (1) (CitH4= citric acid), was dispersed in sodium lauryl sulphate (SLS) to form the micelle of SLS@[Zn3(CitH)2] (2). This material 2 was incorporated in hydrogel made by hydroxyethyl-methacrylate (HEMA), an ingredient of contact lenses, toward the formation of pHEMA@(SLS@[Zn3(CitH)2]) (3). Samples of 1 and 2 were characterized by UV-Vis, 1H-NMR, FT-IR, FT-Raman, single crystal X-ray crystallography, X-ray fluorescence analysis, atomic absorption and TG/DTA/DSC. The antibacterial activity of 1–3 as well as of SLS against Gram-positive (Staphylococcus epidermidis (St. epidermidis) and Staphylococcus aureus (St. aureus)) and Gram-negative (Pseudomonas aeruginosa (PAO1), and Escherichia coli (E. coli)) bacteria was evaluated by the means of minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and inhibitory zone (IZ). 2 showed 10 to 20-fold higher activity than 1 against the bacteria tested. Moreover the 3 decreases the abundance of Gram-positive microbes up to 30% (St. aureus) and up to 20% (PAO1) the Gram-negative ones. The noteworthy antimicrobial activity of the obtained composite 3 suggests an effective antimicrobial additive for infection-free contact lenses.</jats:p> |
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| spelling | Karetsi, V.A. Banti, C.N. Kourkoumelis, N. Papachristodoulou, C. Stalikas, C.D. Raptopoulou, C.P. Psycharis, V. Zoumpoulakis, P. Mavromoustakos, T. Sainis, I. Hadjikakou, S.K. 2079-6382 MDPI AG Pharmacology (medical) Infectious Diseases Microbiology (medical) General Pharmacology, Toxicology and Pharmaceutics Biochemistry Microbiology http://dx.doi.org/10.3390/antibiotics8040213 <jats:p>The [Zn3(CitH)2] (1) (CitH4= citric acid), was dispersed in sodium lauryl sulphate (SLS) to form the micelle of SLS@[Zn3(CitH)2] (2). This material 2 was incorporated in hydrogel made by hydroxyethyl-methacrylate (HEMA), an ingredient of contact lenses, toward the formation of pHEMA@(SLS@[Zn3(CitH)2]) (3). Samples of 1 and 2 were characterized by UV-Vis, 1H-NMR, FT-IR, FT-Raman, single crystal X-ray crystallography, X-ray fluorescence analysis, atomic absorption and TG/DTA/DSC. The antibacterial activity of 1–3 as well as of SLS against Gram-positive (Staphylococcus epidermidis (St. epidermidis) and Staphylococcus aureus (St. aureus)) and Gram-negative (Pseudomonas aeruginosa (PAO1), and Escherichia coli (E. coli)) bacteria was evaluated by the means of minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and inhibitory zone (IZ). 2 showed 10 to 20-fold higher activity than 1 against the bacteria tested. Moreover the 3 decreases the abundance of Gram-positive microbes up to 30% (St. aureus) and up to 20% (PAO1) the Gram-negative ones. The noteworthy antimicrobial activity of the obtained composite 3 suggests an effective antimicrobial additive for infection-free contact lenses.</jats:p> An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens Antibiotics |
| spellingShingle | Karetsi, V.A., Banti, C.N., Kourkoumelis, N., Papachristodoulou, C., Stalikas, C.D., Raptopoulou, C.P., Psycharis, V., Zoumpoulakis, P., Mavromoustakos, T., Sainis, I., Hadjikakou, S.K., Antibiotics, An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens, Pharmacology (medical), Infectious Diseases, Microbiology (medical), General Pharmacology, Toxicology and Pharmaceutics, Biochemistry, Microbiology |
| title | An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| title_full | An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| title_fullStr | An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| title_full_unstemmed | An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| title_short | An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| title_sort | an efficient disinfectant, composite material {sls@[zn3(cith)2]} as ingredient for development of sterilized and non infectious contact lens |
| title_unstemmed | An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens |
| topic | Pharmacology (medical), Infectious Diseases, Microbiology (medical), General Pharmacology, Toxicology and Pharmaceutics, Biochemistry, Microbiology |
| url | http://dx.doi.org/10.3390/antibiotics8040213 |