author_facet Takkar, Nidhi
Takkar, Jai Prakash
Padmakumar, R
Patil, Navin A
Rao, Karthik N
Bhattacharje, Dipanjan
Takkar, Nidhi
Takkar, Jai Prakash
Padmakumar, R
Patil, Navin A
Rao, Karthik N
Bhattacharje, Dipanjan
author Takkar, Nidhi
Takkar, Jai Prakash
Padmakumar, R
Patil, Navin A
Rao, Karthik N
Bhattacharje, Dipanjan
spellingShingle Takkar, Nidhi
Takkar, Jai Prakash
Padmakumar, R
Patil, Navin A
Rao, Karthik N
Bhattacharje, Dipanjan
Romanian Journal of Diabetes Nutrition and Metabolic Diseases
Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
author_sort takkar, nidhi
spelling Takkar, Nidhi Takkar, Jai Prakash Padmakumar, R Patil, Navin A Rao, Karthik N Bhattacharje, Dipanjan 2284-6417 Walter de Gruyter GmbH http://dx.doi.org/10.1515/rjdnmd-2017-0034 <jats:title>Abstract</jats:title> <jats:p> <jats:bold>Background and Aims:</jats:bold> Autonomic dysfunction in type 2 diabetes mellitus (DM) patients may translate into an increased cardiovascular morbidity and mortality. Autonomic system regulates ‘heart rate recovery’ (HRR), an important predictor of cardiovascular mortality, which can be assessed using the exercise electrocardiogram (ECG). Hence, utilizing HRR, this study assessed the autonomic function of the cardiovascular system after one minute of exercise stress test in both, patients with and without type 2 DM.</jats:p> <jats:p> <jats:bold>Materials and Methods:</jats:bold> A prospective case control study involving 50 patients with type 2 DM and 50 without type 2 DM, matched for age and sex, was carried out. Each subject underwent an exercise stress test by treadmill using the Bruce protocol. Cardiovascular parameters like heart rate was recorded using a 12 lead ECG along with blood pressure.</jats:p> <jats:p> <jats:bold>Results:</jats:bold> Patients with T2DM had lesser HRR after exercise (p &lt; 0.001). Exercise capacity was significantly reduced among patients with T2DM when compared to controls (p = 0.01). A multiple linear regression analysis (R<jats:sup>2</jats:sup>=0.26) revealed that duration of diabetes (β=−0.02, p=0.048) and resting systolic blood pressure (SBP) (β=−010, p=0.048) are independent predictors of HRR.</jats:p> <jats:p> <jats:bold>Conclusion:</jats:bold> The study revealed HRR to be significantly reduced among patients with type 2 DM. HRR may hint at the presence of cardiac autonomic dysfunction and predict the cardiovascular mortality.</jats:p> Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics Romanian Journal of Diabetes Nutrition and Metabolic Diseases
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title Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title_unstemmed Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title_full Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title_fullStr Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title_full_unstemmed Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title_short Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title_sort assessment of cardiac autonomic function by post exercise heart rate recovery in diabetics
url http://dx.doi.org/10.1515/rjdnmd-2017-0034
publishDate 2017
physical 289-293
description <jats:title>Abstract</jats:title> <jats:p> <jats:bold>Background and Aims:</jats:bold> Autonomic dysfunction in type 2 diabetes mellitus (DM) patients may translate into an increased cardiovascular morbidity and mortality. Autonomic system regulates ‘heart rate recovery’ (HRR), an important predictor of cardiovascular mortality, which can be assessed using the exercise electrocardiogram (ECG). Hence, utilizing HRR, this study assessed the autonomic function of the cardiovascular system after one minute of exercise stress test in both, patients with and without type 2 DM.</jats:p> <jats:p> <jats:bold>Materials and Methods:</jats:bold> A prospective case control study involving 50 patients with type 2 DM and 50 without type 2 DM, matched for age and sex, was carried out. Each subject underwent an exercise stress test by treadmill using the Bruce protocol. Cardiovascular parameters like heart rate was recorded using a 12 lead ECG along with blood pressure.</jats:p> <jats:p> <jats:bold>Results:</jats:bold> Patients with T2DM had lesser HRR after exercise (p &lt; 0.001). Exercise capacity was significantly reduced among patients with T2DM when compared to controls (p = 0.01). A multiple linear regression analysis (R<jats:sup>2</jats:sup>=0.26) revealed that duration of diabetes (β=−0.02, p=0.048) and resting systolic blood pressure (SBP) (β=−010, p=0.048) are independent predictors of HRR.</jats:p> <jats:p> <jats:bold>Conclusion:</jats:bold> The study revealed HRR to be significantly reduced among patients with type 2 DM. HRR may hint at the presence of cardiac autonomic dysfunction and predict the cardiovascular mortality.</jats:p>
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author Takkar, Nidhi, Takkar, Jai Prakash, Padmakumar, R, Patil, Navin A, Rao, Karthik N, Bhattacharje, Dipanjan
author_facet Takkar, Nidhi, Takkar, Jai Prakash, Padmakumar, R, Patil, Navin A, Rao, Karthik N, Bhattacharje, Dipanjan, Takkar, Nidhi, Takkar, Jai Prakash, Padmakumar, R, Patil, Navin A, Rao, Karthik N, Bhattacharje, Dipanjan
author_sort takkar, nidhi
container_issue 4
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container_title Romanian Journal of Diabetes Nutrition and Metabolic Diseases
container_volume 24
description <jats:title>Abstract</jats:title> <jats:p> <jats:bold>Background and Aims:</jats:bold> Autonomic dysfunction in type 2 diabetes mellitus (DM) patients may translate into an increased cardiovascular morbidity and mortality. Autonomic system regulates ‘heart rate recovery’ (HRR), an important predictor of cardiovascular mortality, which can be assessed using the exercise electrocardiogram (ECG). Hence, utilizing HRR, this study assessed the autonomic function of the cardiovascular system after one minute of exercise stress test in both, patients with and without type 2 DM.</jats:p> <jats:p> <jats:bold>Materials and Methods:</jats:bold> A prospective case control study involving 50 patients with type 2 DM and 50 without type 2 DM, matched for age and sex, was carried out. Each subject underwent an exercise stress test by treadmill using the Bruce protocol. Cardiovascular parameters like heart rate was recorded using a 12 lead ECG along with blood pressure.</jats:p> <jats:p> <jats:bold>Results:</jats:bold> Patients with T2DM had lesser HRR after exercise (p &lt; 0.001). Exercise capacity was significantly reduced among patients with T2DM when compared to controls (p = 0.01). A multiple linear regression analysis (R<jats:sup>2</jats:sup>=0.26) revealed that duration of diabetes (β=−0.02, p=0.048) and resting systolic blood pressure (SBP) (β=−010, p=0.048) are independent predictors of HRR.</jats:p> <jats:p> <jats:bold>Conclusion:</jats:bold> The study revealed HRR to be significantly reduced among patients with type 2 DM. HRR may hint at the presence of cardiac autonomic dysfunction and predict the cardiovascular mortality.</jats:p>
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spelling Takkar, Nidhi Takkar, Jai Prakash Padmakumar, R Patil, Navin A Rao, Karthik N Bhattacharje, Dipanjan 2284-6417 Walter de Gruyter GmbH http://dx.doi.org/10.1515/rjdnmd-2017-0034 <jats:title>Abstract</jats:title> <jats:p> <jats:bold>Background and Aims:</jats:bold> Autonomic dysfunction in type 2 diabetes mellitus (DM) patients may translate into an increased cardiovascular morbidity and mortality. Autonomic system regulates ‘heart rate recovery’ (HRR), an important predictor of cardiovascular mortality, which can be assessed using the exercise electrocardiogram (ECG). Hence, utilizing HRR, this study assessed the autonomic function of the cardiovascular system after one minute of exercise stress test in both, patients with and without type 2 DM.</jats:p> <jats:p> <jats:bold>Materials and Methods:</jats:bold> A prospective case control study involving 50 patients with type 2 DM and 50 without type 2 DM, matched for age and sex, was carried out. Each subject underwent an exercise stress test by treadmill using the Bruce protocol. Cardiovascular parameters like heart rate was recorded using a 12 lead ECG along with blood pressure.</jats:p> <jats:p> <jats:bold>Results:</jats:bold> Patients with T2DM had lesser HRR after exercise (p &lt; 0.001). Exercise capacity was significantly reduced among patients with T2DM when compared to controls (p = 0.01). A multiple linear regression analysis (R<jats:sup>2</jats:sup>=0.26) revealed that duration of diabetes (β=−0.02, p=0.048) and resting systolic blood pressure (SBP) (β=−010, p=0.048) are independent predictors of HRR.</jats:p> <jats:p> <jats:bold>Conclusion:</jats:bold> The study revealed HRR to be significantly reduced among patients with type 2 DM. HRR may hint at the presence of cardiac autonomic dysfunction and predict the cardiovascular mortality.</jats:p> Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics Romanian Journal of Diabetes Nutrition and Metabolic Diseases
spellingShingle Takkar, Nidhi, Takkar, Jai Prakash, Padmakumar, R, Patil, Navin A, Rao, Karthik N, Bhattacharje, Dipanjan, Romanian Journal of Diabetes Nutrition and Metabolic Diseases, Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title_full Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title_fullStr Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title_full_unstemmed Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title_short Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
title_sort assessment of cardiac autonomic function by post exercise heart rate recovery in diabetics
title_unstemmed Assessment of Cardiac Autonomic Function by Post Exercise Heart Rate Recovery in Diabetics
url http://dx.doi.org/10.1515/rjdnmd-2017-0034