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Williams, Gareth
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Williams, Gareth
author Gill, Geoffrey V
Williams, Gareth
spellingShingle Gill, Geoffrey V
Williams, Gareth
Postgraduate Medical Journal
Brittle Addison's disease: a new variation on a familiar theme
General Medicine
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spelling Gill, Geoffrey V Williams, Gareth 1469-0756 0032-5473 Oxford University Press (OUP) General Medicine http://dx.doi.org/10.1136/pmj.76.893.166 <jats:title>Summary</jats:title> <jats:p>Unstable and unpredictable disease control in diabetes or asthma, with frequent hospitalisations, is frequently referred to as ‘brittle’. We describe two cases of Addison's disease with recurrent hospitalisations in hypo-adrenal crises. Both patients had significant psychosocial disruption, and failure to take hydrocortisone replacement therapy was admitted in one and biochemically proven in the other. We propose that ‘brittle’ Addison's disease in these cases was due to poor treatment compliance related to psychosocial factors. These features have particular similarities with the syndrome of brittle diabetes.</jats:p> Brittle Addison's disease: a new variation on a familiar theme Postgraduate Medical Journal
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title Brittle Addison's disease: a new variation on a familiar theme
title_unstemmed Brittle Addison's disease: a new variation on a familiar theme
title_full Brittle Addison's disease: a new variation on a familiar theme
title_fullStr Brittle Addison's disease: a new variation on a familiar theme
title_full_unstemmed Brittle Addison's disease: a new variation on a familiar theme
title_short Brittle Addison's disease: a new variation on a familiar theme
title_sort brittle addison's disease: a new variation on a familiar theme
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publishDate 2000
physical 166-167
description <jats:title>Summary</jats:title> <jats:p>Unstable and unpredictable disease control in diabetes or asthma, with frequent hospitalisations, is frequently referred to as ‘brittle’. We describe two cases of Addison's disease with recurrent hospitalisations in hypo-adrenal crises. Both patients had significant psychosocial disruption, and failure to take hydrocortisone replacement therapy was admitted in one and biochemically proven in the other. We propose that ‘brittle’ Addison's disease in these cases was due to poor treatment compliance related to psychosocial factors. These features have particular similarities with the syndrome of brittle diabetes.</jats:p>
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description <jats:title>Summary</jats:title> <jats:p>Unstable and unpredictable disease control in diabetes or asthma, with frequent hospitalisations, is frequently referred to as ‘brittle’. We describe two cases of Addison's disease with recurrent hospitalisations in hypo-adrenal crises. Both patients had significant psychosocial disruption, and failure to take hydrocortisone replacement therapy was admitted in one and biochemically proven in the other. We propose that ‘brittle’ Addison's disease in these cases was due to poor treatment compliance related to psychosocial factors. These features have particular similarities with the syndrome of brittle diabetes.</jats:p>
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spelling Gill, Geoffrey V Williams, Gareth 1469-0756 0032-5473 Oxford University Press (OUP) General Medicine http://dx.doi.org/10.1136/pmj.76.893.166 <jats:title>Summary</jats:title> <jats:p>Unstable and unpredictable disease control in diabetes or asthma, with frequent hospitalisations, is frequently referred to as ‘brittle’. We describe two cases of Addison's disease with recurrent hospitalisations in hypo-adrenal crises. Both patients had significant psychosocial disruption, and failure to take hydrocortisone replacement therapy was admitted in one and biochemically proven in the other. We propose that ‘brittle’ Addison's disease in these cases was due to poor treatment compliance related to psychosocial factors. These features have particular similarities with the syndrome of brittle diabetes.</jats:p> Brittle Addison's disease: a new variation on a familiar theme Postgraduate Medical Journal
spellingShingle Gill, Geoffrey V, Williams, Gareth, Postgraduate Medical Journal, Brittle Addison's disease: a new variation on a familiar theme, General Medicine
title Brittle Addison's disease: a new variation on a familiar theme
title_full Brittle Addison's disease: a new variation on a familiar theme
title_fullStr Brittle Addison's disease: a new variation on a familiar theme
title_full_unstemmed Brittle Addison's disease: a new variation on a familiar theme
title_short Brittle Addison's disease: a new variation on a familiar theme
title_sort brittle addison's disease: a new variation on a familiar theme
title_unstemmed Brittle Addison's disease: a new variation on a familiar theme
topic General Medicine
url http://dx.doi.org/10.1136/pmj.76.893.166