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Observations of Shear Stress Effects on Staphylococcus aureus Biofilm Formation
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| Zeitschriftentitel: | mSphere |
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| Personen und Körperschaften: | , , , , |
| In: | mSphere, 4, 2019, 4 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Society for Microbiology
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| Schlagwörter: |
| Zusammenfassung: | <jats:p> It is well known that flow plays an important role in the formation, transportation, and dispersion of <jats:named-content content-type="genus-species">Staphylococcus aureus</jats:named-content> biofilms. What was heretofore not known was that the formation of tower structures in these biofilms is strongly shear stress dependent; there is, in fact, a narrow range of shear stresses in which the phenomenon occurs. This work quantifies the observed shear dependence in terms of cell growth, distribution, and fluid mechanics. It represents an important first step in opening up a line of questioning as to the interaction of fluid forces and their influence on the dynamics of tower formation, break-off, and transportation in biofilms by identifying the parameter space in which this phenomenon occurs. We have also introduced state-of-the-art flow measurement techniques to address this problem. </jats:p> |
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| ISSN: |
2379-5042
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| DOI: | 10.1128/msphere.00372-19 |