Eintrag weiter verarbeiten
Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection
Gespeichert in:
| Zeitschriftentitel: | Infection and Immunity |
|---|---|
| Personen und Körperschaften: | , , , |
| In: | Infection and Immunity, 42, 1983, 2, S. 567-573 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Society for Microbiology
|
| Schlagwörter: |
| author_facet |
Sakuma, T Suenaga, T Yoshida, I Azuma, M Sakuma, T Suenaga, T Yoshida, I Azuma, M |
|---|---|
| author |
Sakuma, T Suenaga, T Yoshida, I Azuma, M |
| spellingShingle |
Sakuma, T Suenaga, T Yoshida, I Azuma, M Infection and Immunity Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection Infectious Diseases Immunology Microbiology Parasitology |
| author_sort |
sakuma, t |
| spelling |
Sakuma, T Suenaga, T Yoshida, I Azuma, M 0019-9567 1098-5522 American Society for Microbiology Infectious Diseases Immunology Microbiology Parasitology http://dx.doi.org/10.1128/iai.42.2.567-573.1983 <jats:p>The mechanism of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection was investigated by determining the effect of splenectomy, antithymocyte serum, and antimacrophage serum on resistance. It was greatly reduced by these treatments, not only in normal mice, but also in mice treated with live or heat-inactivated BCG. Production of circulating interferon by ectromelia virus and Newcastle disease virus was augmented in BCG-treated mice and was markedly depressed by splenectomy and antithymocyte and antimacrophage serum treatments in both BCG-treated and normal mice. Carbon clearance activity was activated in BCG-treated mice, but splenectomy did not influence phagocytic activity. These results suggest that augmented interferon production in the spleens of BCG-treated mice plays a major role in enhanced resistance. Other possible mechanisms are discussed.</jats:p> Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection Infection and Immunity |
| doi_str_mv |
10.1128/iai.42.2.567-573.1983 |
| facet_avail |
Online Free |
| finc_class_facet |
Medizin Biologie |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTEyOC9pYWkuNDIuMi41NjctNTczLjE5ODM |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTEyOC9pYWkuNDIuMi41NjctNTczLjE5ODM |
| institution |
DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Zi4 DE-Gla1 DE-15 DE-Pl11 DE-Rs1 DE-14 FID-BBI-DE-23 DE-105 DE-Ch1 DE-L229 |
| imprint |
American Society for Microbiology, 1983 |
| imprint_str_mv |
American Society for Microbiology, 1983 |
| issn |
0019-9567 1098-5522 |
| issn_str_mv |
0019-9567 1098-5522 |
| language |
English |
| mega_collection |
American Society for Microbiology (CrossRef) |
| match_str |
sakuma1983mechanismsofenhancedresistanceofmycobacteriumbovisbcgtreatedmicetoectromeliavirusinfection |
| publishDateSort |
1983 |
| publisher |
American Society for Microbiology |
| recordtype |
ai |
| record_format |
ai |
| series |
Infection and Immunity |
| source_id |
49 |
| title |
Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| title_unstemmed |
Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| title_full |
Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| title_fullStr |
Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| title_full_unstemmed |
Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| title_short |
Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| title_sort |
mechanisms of enhanced resistance of mycobacterium bovis bcg-treated mice to ectromelia virus infection |
| topic |
Infectious Diseases Immunology Microbiology Parasitology |
| url |
http://dx.doi.org/10.1128/iai.42.2.567-573.1983 |
| publishDate |
1983 |
| physical |
567-573 |
| description |
<jats:p>The mechanism of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection was investigated by determining the effect of splenectomy, antithymocyte serum, and antimacrophage serum on resistance. It was greatly reduced by these treatments, not only in normal mice, but also in mice treated with live or heat-inactivated BCG. Production of circulating interferon by ectromelia virus and Newcastle disease virus was augmented in BCG-treated mice and was markedly depressed by splenectomy and antithymocyte and antimacrophage serum treatments in both BCG-treated and normal mice. Carbon clearance activity was activated in BCG-treated mice, but splenectomy did not influence phagocytic activity. These results suggest that augmented interferon production in the spleens of BCG-treated mice plays a major role in enhanced resistance. Other possible mechanisms are discussed.</jats:p> |
| container_issue |
2 |
| container_start_page |
567 |
| container_title |
Infection and Immunity |
| container_volume |
42 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792339664531619840 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T15:51:44.246Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Mechanisms+of+enhanced+resistance+of+Mycobacterium+bovis+BCG-treated+mice+to+ectromelia+virus+infection&rft.date=1983-11-01&genre=article&issn=1098-5522&volume=42&issue=2&spage=567&epage=573&pages=567-573&jtitle=Infection+and+Immunity&atitle=Mechanisms+of+enhanced+resistance+of+Mycobacterium+bovis+BCG-treated+mice+to+ectromelia+virus+infection&aulast=Azuma&aufirst=M&rft_id=info%3Adoi%2F10.1128%2Fiai.42.2.567-573.1983&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792339664531619840 |
| author | Sakuma, T, Suenaga, T, Yoshida, I, Azuma, M |
| author_facet | Sakuma, T, Suenaga, T, Yoshida, I, Azuma, M, Sakuma, T, Suenaga, T, Yoshida, I, Azuma, M |
| author_sort | sakuma, t |
| container_issue | 2 |
| container_start_page | 567 |
| container_title | Infection and Immunity |
| container_volume | 42 |
| description | <jats:p>The mechanism of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection was investigated by determining the effect of splenectomy, antithymocyte serum, and antimacrophage serum on resistance. It was greatly reduced by these treatments, not only in normal mice, but also in mice treated with live or heat-inactivated BCG. Production of circulating interferon by ectromelia virus and Newcastle disease virus was augmented in BCG-treated mice and was markedly depressed by splenectomy and antithymocyte and antimacrophage serum treatments in both BCG-treated and normal mice. Carbon clearance activity was activated in BCG-treated mice, but splenectomy did not influence phagocytic activity. These results suggest that augmented interferon production in the spleens of BCG-treated mice plays a major role in enhanced resistance. Other possible mechanisms are discussed.</jats:p> |
| doi_str_mv | 10.1128/iai.42.2.567-573.1983 |
| facet_avail | Online, Free |
| finc_class_facet | Medizin, Biologie |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTEyOC9pYWkuNDIuMi41NjctNTczLjE5ODM |
| imprint | American Society for Microbiology, 1983 |
| imprint_str_mv | American Society for Microbiology, 1983 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Zi4, DE-Gla1, DE-15, DE-Pl11, DE-Rs1, DE-14, FID-BBI-DE-23, DE-105, DE-Ch1, DE-L229 |
| issn | 0019-9567, 1098-5522 |
| issn_str_mv | 0019-9567, 1098-5522 |
| language | English |
| last_indexed | 2024-03-01T15:51:44.246Z |
| match_str | sakuma1983mechanismsofenhancedresistanceofmycobacteriumbovisbcgtreatedmicetoectromeliavirusinfection |
| mega_collection | American Society for Microbiology (CrossRef) |
| physical | 567-573 |
| publishDate | 1983 |
| publishDateSort | 1983 |
| publisher | American Society for Microbiology |
| record_format | ai |
| recordtype | ai |
| series | Infection and Immunity |
| source_id | 49 |
| spelling | Sakuma, T Suenaga, T Yoshida, I Azuma, M 0019-9567 1098-5522 American Society for Microbiology Infectious Diseases Immunology Microbiology Parasitology http://dx.doi.org/10.1128/iai.42.2.567-573.1983 <jats:p>The mechanism of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection was investigated by determining the effect of splenectomy, antithymocyte serum, and antimacrophage serum on resistance. It was greatly reduced by these treatments, not only in normal mice, but also in mice treated with live or heat-inactivated BCG. Production of circulating interferon by ectromelia virus and Newcastle disease virus was augmented in BCG-treated mice and was markedly depressed by splenectomy and antithymocyte and antimacrophage serum treatments in both BCG-treated and normal mice. Carbon clearance activity was activated in BCG-treated mice, but splenectomy did not influence phagocytic activity. These results suggest that augmented interferon production in the spleens of BCG-treated mice plays a major role in enhanced resistance. Other possible mechanisms are discussed.</jats:p> Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection Infection and Immunity |
| spellingShingle | Sakuma, T, Suenaga, T, Yoshida, I, Azuma, M, Infection and Immunity, Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection, Infectious Diseases, Immunology, Microbiology, Parasitology |
| title | Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| title_full | Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| title_fullStr | Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| title_full_unstemmed | Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| title_short | Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| title_sort | mechanisms of enhanced resistance of mycobacterium bovis bcg-treated mice to ectromelia virus infection |
| title_unstemmed | Mechanisms of enhanced resistance of Mycobacterium bovis BCG-treated mice to ectromelia virus infection |
| topic | Infectious Diseases, Immunology, Microbiology, Parasitology |
| url | http://dx.doi.org/10.1128/iai.42.2.567-573.1983 |