Insight into the Role of HOG Pathway Components Ssk2p, Pbs2p, and Hog1p in the Opportunistic Yeast Candida lusitaniae

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Bibliographische Detailangaben
Zeitschriftentitel:	Eukaryotic Cell
Personen und Körperschaften:	Boisnard, Stéphanie, Ruprich-Robert, Gwenaël, Florent, Martine, Da Silva, Bruno, Chapeland-Leclerc, Florence, Papon, Nicolas
In:	Eukaryotic Cell, 7, 2008, 12, S. 2179-2183
Format:	E-Article
Sprache:	Englisch
veröffentlicht:	American Society for Microbiology
Schlagwörter:	Molecular Biology General Medicine Microbiology

Details
Zusammenfassung:	<jats:title>ABSTRACT</jats:title> <jats:p> In the present study, we have investigated the role of <jats:italic>SSK2</jats:italic> , <jats:italic>PBS2</jats:italic> , and <jats:italic>HOG1</jats:italic> , encoding modules of the high-osmolarity-glycerol mitogen-activated protein kinase pathway in <jats:italic>Candida lusitaniae</jats:italic> . Functional analysis of mutants indicated that Ssk2p, Pbs2p, and Hog1p are involved in osmotolerance, drug sensitivity, and heavy metal tolerance but not in oxidant stress adaptation. </jats:p>
Umfang:	2179-2183
ISSN:	1535-9778 1535-9786
DOI:	10.1128/ec.00262-08