Enhancement of the Diversity of Polyoxins by a Thymine-7-Hydroxylase Homolog outside the Polyoxin Biosynthesis Gene Cluster

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Bibliographische Detailangaben
Zeitschriftentitel:	Applied and Environmental Microbiology
Personen und Körperschaften:	Zhao, Changming, Huang, Tingting, Chen, Wenqing, Deng, Zixin
In:	Applied and Environmental Microbiology, 76, 2010, 21, S. 7343-7347
Format:	E-Article
Sprache:	Englisch
veröffentlicht:	American Society for Microbiology
Schlagwörter:	Ecology Applied Microbiology and Biotechnology Food Science Biotechnology

Details
Zusammenfassung:	<jats:title>ABSTRACT</jats:title> <jats:p> Polyoxins consist of 14 structurally variable components which differentiate at three branch sites of the carbon skeleton. Open reading frame (ORF) SAV_4805 of <jats:italic>Streptomyces avermitilis</jats:italic> , showing similarity to thymine-7-hydroxylase, was proved to enhance the diversity of polyoxins at the C-5 site of the 1-(5′-amino-5′-deoxy-β- <jats:sc>d</jats:sc> -allofuranuronosyl) pyrimidine moiety. </jats:p>
Umfang:	7343-7347
ISSN:	0099-2240 1098-5336
DOI:	10.1128/aem.01257-10