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Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains
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| Zeitschriftentitel: | Antimicrobial Agents and Chemotherapy |
|---|---|
| Personen und Körperschaften: | , , , , |
| In: | Antimicrobial Agents and Chemotherapy, 49, 2005, 8, S. 3501-3512 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Society for Microbiology
|
| Schlagwörter: |
| author_facet |
Sader, Helio S. Fritsche, Thomas R. Kaniga, Koné Ge, Yigong Jones, Ronald N. Sader, Helio S. Fritsche, Thomas R. Kaniga, Koné Ge, Yigong Jones, Ronald N. |
|---|---|
| author |
Sader, Helio S. Fritsche, Thomas R. Kaniga, Koné Ge, Yigong Jones, Ronald N. |
| spellingShingle |
Sader, Helio S. Fritsche, Thomas R. Kaniga, Koné Ge, Yigong Jones, Ronald N. Antimicrobial Agents and Chemotherapy Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains Infectious Diseases Pharmacology (medical) Pharmacology |
| author_sort |
sader, helio s. |
| spelling |
Sader, Helio S. Fritsche, Thomas R. Kaniga, Koné Ge, Yigong Jones, Ronald N. 0066-4804 1098-6596 American Society for Microbiology Infectious Diseases Pharmacology (medical) Pharmacology http://dx.doi.org/10.1128/aac.49.8.3501-3512.2005 <jats:title>ABSTRACT</jats:title> <jats:p> PPI-0903M is a novel <jats:italic>N</jats:italic> -phosphono-type cephalosporin active against oxacillin-resistant staphylococci and many other gram-positive organisms. This study evaluated the in vitro activity and spectrum of PPI-0903M against 1,478 recent clinical isolates collected from 80 medical centers (22 countries). PPI-0903M demonstrated broader in vitro activity against gram-positive bacteria, particularly against multidrug-resistant staphylococci and streptococci of current clinical concern, than currently available extended-spectrum cephalosporins while maintaining similar activity against gram-negative pathogens. </jats:p> Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains Antimicrobial Agents and Chemotherapy |
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Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| title_unstemmed |
Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| title_full |
Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| title_fullStr |
Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| title_full_unstemmed |
Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| title_short |
Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| title_sort |
antimicrobial activity and spectrum of ppi-0903m (t-91825), a novel cephalosporin, tested against a worldwide collection of clinical strains |
| topic |
Infectious Diseases Pharmacology (medical) Pharmacology |
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http://dx.doi.org/10.1128/aac.49.8.3501-3512.2005 |
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2005 |
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3501-3512 |
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<jats:title>ABSTRACT</jats:title>
<jats:p>
PPI-0903M is a novel
<jats:italic>N</jats:italic>
-phosphono-type cephalosporin active against oxacillin-resistant staphylococci and many other gram-positive organisms. This study evaluated the in vitro activity and spectrum of PPI-0903M against 1,478 recent clinical isolates collected from 80 medical centers (22 countries). PPI-0903M demonstrated broader in vitro activity against gram-positive bacteria, particularly against multidrug-resistant staphylococci and streptococci of current clinical concern, than currently available extended-spectrum cephalosporins while maintaining similar activity against gram-negative pathogens.
</jats:p> |
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| author | Sader, Helio S., Fritsche, Thomas R., Kaniga, Koné, Ge, Yigong, Jones, Ronald N. |
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| description | <jats:title>ABSTRACT</jats:title> <jats:p> PPI-0903M is a novel <jats:italic>N</jats:italic> -phosphono-type cephalosporin active against oxacillin-resistant staphylococci and many other gram-positive organisms. This study evaluated the in vitro activity and spectrum of PPI-0903M against 1,478 recent clinical isolates collected from 80 medical centers (22 countries). PPI-0903M demonstrated broader in vitro activity against gram-positive bacteria, particularly against multidrug-resistant staphylococci and streptococci of current clinical concern, than currently available extended-spectrum cephalosporins while maintaining similar activity against gram-negative pathogens. </jats:p> |
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| spelling | Sader, Helio S. Fritsche, Thomas R. Kaniga, Koné Ge, Yigong Jones, Ronald N. 0066-4804 1098-6596 American Society for Microbiology Infectious Diseases Pharmacology (medical) Pharmacology http://dx.doi.org/10.1128/aac.49.8.3501-3512.2005 <jats:title>ABSTRACT</jats:title> <jats:p> PPI-0903M is a novel <jats:italic>N</jats:italic> -phosphono-type cephalosporin active against oxacillin-resistant staphylococci and many other gram-positive organisms. This study evaluated the in vitro activity and spectrum of PPI-0903M against 1,478 recent clinical isolates collected from 80 medical centers (22 countries). PPI-0903M demonstrated broader in vitro activity against gram-positive bacteria, particularly against multidrug-resistant staphylococci and streptococci of current clinical concern, than currently available extended-spectrum cephalosporins while maintaining similar activity against gram-negative pathogens. </jats:p> Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains Antimicrobial Agents and Chemotherapy |
| spellingShingle | Sader, Helio S., Fritsche, Thomas R., Kaniga, Koné, Ge, Yigong, Jones, Ronald N., Antimicrobial Agents and Chemotherapy, Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains, Infectious Diseases, Pharmacology (medical), Pharmacology |
| title | Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| title_full | Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| title_fullStr | Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| title_full_unstemmed | Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| title_short | Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| title_sort | antimicrobial activity and spectrum of ppi-0903m (t-91825), a novel cephalosporin, tested against a worldwide collection of clinical strains |
| title_unstemmed | Antimicrobial Activity and Spectrum of PPI-0903M (T-91825), a Novel Cephalosporin, Tested against a Worldwide Collection of Clinical Strains |
| topic | Infectious Diseases, Pharmacology (medical), Pharmacology |
| url | http://dx.doi.org/10.1128/aac.49.8.3501-3512.2005 |