Emergence of Metallo-β-Lactamase NDM-1-Producing Multidrug-Resistant Escherichia coli in Australia

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Bibliographische Detailangaben
Zeitschriftentitel:	Antimicrobial Agents and Chemotherapy
Personen und Körperschaften:	Poirel, Laurent, Lagrutta, Emilie, Taylor, Peter, Pham, Jeanette, Nordmann, Patrice
In:	Antimicrobial Agents and Chemotherapy, 54, 2010, 11, S. 4914-4916
Format:	E-Article
Sprache:	Englisch
veröffentlicht:	American Society for Microbiology
Schlagwörter:	Infectious Diseases Pharmacology (medical) Pharmacology

Details
Zusammenfassung:	<jats:title>ABSTRACT</jats:title> <jats:p> A multidrug-resistant <jats:italic>Escherichia coli</jats:italic> isolate recovered in Australia produced a carbapenem-hydrolyzing β-lactamase. Molecular investigations revealed the first identification of the <jats:italic>bla</jats:italic> <jats:sub>NDM-1</jats:sub> metallo-β-lactamase gene in that country. In addition, this <jats:italic>E. coli</jats:italic> isolate expressed the extended-spectrum β-lactamase CTX-M-15, together with two 16S rRNA methylases, namely, ArmA and RmtB, conferring a high level of resistance to aminoglycosides. </jats:p>
Umfang:	4914-4916
ISSN:	0066-4804 1098-6596
DOI:	10.1128/aac.00878-10