Eintrag weiter verarbeiten
Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia
Gespeichert in:
| Zeitschriftentitel: | Anaesthesia |
|---|---|
| Personen und Körperschaften: | , , , , |
| In: | Anaesthesia, 72, 2017, 11, S. 1357-1364 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Onodi, C. Bühler, P. K. Thomas, J. Schmitz, A. Weiss, M. Onodi, C. Bühler, P. K. Thomas, J. Schmitz, A. Weiss, M. |
|---|---|
| author |
Onodi, C. Bühler, P. K. Thomas, J. Schmitz, A. Weiss, M. |
| spellingShingle |
Onodi, C. Bühler, P. K. Thomas, J. Schmitz, A. Weiss, M. Anaesthesia Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia Anesthesiology and Pain Medicine |
| author_sort |
onodi, c. |
| spelling |
Onodi, C. Bühler, P. K. Thomas, J. Schmitz, A. Weiss, M. 0003-2409 1365-2044 Wiley Anesthesiology and Pain Medicine http://dx.doi.org/10.1111/anae.13969 <jats:title>Summary</jats:title><jats:p>Capnography (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) is routinely used as a non‐invasive estimate of arterial carbon dioxide (Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) levels in order to modify ventilatory settings, whereby it is assumed that there is a positive gap between Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> and ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> of approximately 0.5 <jats:styled-content style="fixed-case">kP</jats:styled-content>a. However, negative values (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> > Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) can be observed. We retrospectively analysed arterial to end‐tidal carbon dioxide differences in 799 children undergoing general anaesthesia with mechanical ventilation of the lungs in order to elucidate predictors for a negative gap. A total of 2452 blood gas analysis readings with complete vital sign monitoring, anaesthesia gas analysis and spirometry data were analysed. Mean arterial to end‐tidal carbon dioxide difference was −0.18 <jats:styled-content style="fixed-case">kP</jats:styled-content>a (limits of 95% agreement −1.10 to 0.74) and 71.2% of samples demonstrated negative values. The intercept model revealed Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> to be the strongest predictor for a negative Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>‐ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> difference. A decrease in Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> by 1 <jats:styled-content style="fixed-case">kP</jats:styled-content>a resulted in a decrease in the Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>‐ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> difference by 0.23 <jats:styled-content style="fixed-case">kP</jats:styled-content>a. This study demonstrates that ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> monitoring in children whose lungs are mechanically ventilated may paradoxically lead to overestimation of ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> > Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) with a subsequent risk of unrecognised hypocarbia.</jats:p> Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia Anaesthesia |
| doi_str_mv |
10.1111/anae.13969 |
| facet_avail |
Online Free |
| finc_class_facet |
Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9hbmFlLjEzOTY5 |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9hbmFlLjEzOTY5 |
| institution |
DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 |
| imprint |
Wiley, 2017 |
| imprint_str_mv |
Wiley, 2017 |
| issn |
0003-2409 1365-2044 |
| issn_str_mv |
0003-2409 1365-2044 |
| language |
English |
| mega_collection |
Wiley (CrossRef) |
| match_str |
onodi2017arterialtoendtidalcarbondioxidedifferenceinchildrenundergoingmechanicalventilationofthelungsduringgeneralanaesthesia |
| publishDateSort |
2017 |
| publisher |
Wiley |
| recordtype |
ai |
| record_format |
ai |
| series |
Anaesthesia |
| source_id |
49 |
| title |
Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_unstemmed |
Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_full |
Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_fullStr |
Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_full_unstemmed |
Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_short |
Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_sort |
arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| topic |
Anesthesiology and Pain Medicine |
| url |
http://dx.doi.org/10.1111/anae.13969 |
| publishDate |
2017 |
| physical |
1357-1364 |
| description |
<jats:title>Summary</jats:title><jats:p>Capnography (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) is routinely used as a non‐invasive estimate of arterial carbon dioxide (Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) levels in order to modify ventilatory settings, whereby it is assumed that there is a positive gap between Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> and ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> of approximately 0.5 <jats:styled-content style="fixed-case">kP</jats:styled-content>a. However, negative values (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> > Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) can be observed. We retrospectively analysed arterial to end‐tidal carbon dioxide differences in 799 children undergoing general anaesthesia with mechanical ventilation of the lungs in order to elucidate predictors for a negative gap. A total of 2452 blood gas analysis readings with complete vital sign monitoring, anaesthesia gas analysis and spirometry data were analysed. Mean arterial to end‐tidal carbon dioxide difference was −0.18 <jats:styled-content style="fixed-case">kP</jats:styled-content>a (limits of 95% agreement −1.10 to 0.74) and 71.2% of samples demonstrated negative values. The intercept model revealed Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> to be the strongest predictor for a negative Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>‐ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> difference. A decrease in Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> by 1 <jats:styled-content style="fixed-case">kP</jats:styled-content>a resulted in a decrease in the Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>‐ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> difference by 0.23 <jats:styled-content style="fixed-case">kP</jats:styled-content>a. This study demonstrates that ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> monitoring in children whose lungs are mechanically ventilated may paradoxically lead to overestimation of ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> > Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) with a subsequent risk of unrecognised hypocarbia.</jats:p> |
| container_issue |
11 |
| container_start_page |
1357 |
| container_title |
Anaesthesia |
| container_volume |
72 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792345380985241601 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T17:22:12.273Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Arterial+to+end%E2%80%90tidal+carbon+dioxide+difference+in+children+undergoing+mechanical+ventilation+of+the+lungs+during+general+anaesthesia&rft.date=2017-11-01&genre=article&issn=1365-2044&volume=72&issue=11&spage=1357&epage=1364&pages=1357-1364&jtitle=Anaesthesia&atitle=Arterial+to+end%E2%80%90tidal+carbon+dioxide+difference+in+children+undergoing+mechanical+ventilation+of+the+lungs+during+general+anaesthesia&aulast=Weiss&aufirst=M.&rft_id=info%3Adoi%2F10.1111%2Fanae.13969&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792345380985241601 |
| author | Onodi, C., Bühler, P. K., Thomas, J., Schmitz, A., Weiss, M. |
| author_facet | Onodi, C., Bühler, P. K., Thomas, J., Schmitz, A., Weiss, M., Onodi, C., Bühler, P. K., Thomas, J., Schmitz, A., Weiss, M. |
| author_sort | onodi, c. |
| container_issue | 11 |
| container_start_page | 1357 |
| container_title | Anaesthesia |
| container_volume | 72 |
| description | <jats:title>Summary</jats:title><jats:p>Capnography (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) is routinely used as a non‐invasive estimate of arterial carbon dioxide (Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) levels in order to modify ventilatory settings, whereby it is assumed that there is a positive gap between Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> and ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> of approximately 0.5 <jats:styled-content style="fixed-case">kP</jats:styled-content>a. However, negative values (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> > Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) can be observed. We retrospectively analysed arterial to end‐tidal carbon dioxide differences in 799 children undergoing general anaesthesia with mechanical ventilation of the lungs in order to elucidate predictors for a negative gap. A total of 2452 blood gas analysis readings with complete vital sign monitoring, anaesthesia gas analysis and spirometry data were analysed. Mean arterial to end‐tidal carbon dioxide difference was −0.18 <jats:styled-content style="fixed-case">kP</jats:styled-content>a (limits of 95% agreement −1.10 to 0.74) and 71.2% of samples demonstrated negative values. The intercept model revealed Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> to be the strongest predictor for a negative Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>‐ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> difference. A decrease in Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> by 1 <jats:styled-content style="fixed-case">kP</jats:styled-content>a resulted in a decrease in the Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>‐ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> difference by 0.23 <jats:styled-content style="fixed-case">kP</jats:styled-content>a. This study demonstrates that ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> monitoring in children whose lungs are mechanically ventilated may paradoxically lead to overestimation of ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> > Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) with a subsequent risk of unrecognised hypocarbia.</jats:p> |
| doi_str_mv | 10.1111/anae.13969 |
| facet_avail | Online, Free |
| finc_class_facet | Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9hbmFlLjEzOTY5 |
| imprint | Wiley, 2017 |
| imprint_str_mv | Wiley, 2017 |
| institution | DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4 |
| issn | 0003-2409, 1365-2044 |
| issn_str_mv | 0003-2409, 1365-2044 |
| language | English |
| last_indexed | 2024-03-01T17:22:12.273Z |
| match_str | onodi2017arterialtoendtidalcarbondioxidedifferenceinchildrenundergoingmechanicalventilationofthelungsduringgeneralanaesthesia |
| mega_collection | Wiley (CrossRef) |
| physical | 1357-1364 |
| publishDate | 2017 |
| publishDateSort | 2017 |
| publisher | Wiley |
| record_format | ai |
| recordtype | ai |
| series | Anaesthesia |
| source_id | 49 |
| spelling | Onodi, C. Bühler, P. K. Thomas, J. Schmitz, A. Weiss, M. 0003-2409 1365-2044 Wiley Anesthesiology and Pain Medicine http://dx.doi.org/10.1111/anae.13969 <jats:title>Summary</jats:title><jats:p>Capnography (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) is routinely used as a non‐invasive estimate of arterial carbon dioxide (Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) levels in order to modify ventilatory settings, whereby it is assumed that there is a positive gap between Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> and ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> of approximately 0.5 <jats:styled-content style="fixed-case">kP</jats:styled-content>a. However, negative values (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> > Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) can be observed. We retrospectively analysed arterial to end‐tidal carbon dioxide differences in 799 children undergoing general anaesthesia with mechanical ventilation of the lungs in order to elucidate predictors for a negative gap. A total of 2452 blood gas analysis readings with complete vital sign monitoring, anaesthesia gas analysis and spirometry data were analysed. Mean arterial to end‐tidal carbon dioxide difference was −0.18 <jats:styled-content style="fixed-case">kP</jats:styled-content>a (limits of 95% agreement −1.10 to 0.74) and 71.2% of samples demonstrated negative values. The intercept model revealed Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> to be the strongest predictor for a negative Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>‐ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> difference. A decrease in Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> by 1 <jats:styled-content style="fixed-case">kP</jats:styled-content>a resulted in a decrease in the Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>‐ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> difference by 0.23 <jats:styled-content style="fixed-case">kP</jats:styled-content>a. This study demonstrates that ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> monitoring in children whose lungs are mechanically ventilated may paradoxically lead to overestimation of ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> (ET<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub> > Pa<jats:styled-content style="fixed-case">CO</jats:styled-content><jats:sub>2</jats:sub>) with a subsequent risk of unrecognised hypocarbia.</jats:p> Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia Anaesthesia |
| spellingShingle | Onodi, C., Bühler, P. K., Thomas, J., Schmitz, A., Weiss, M., Anaesthesia, Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia, Anesthesiology and Pain Medicine |
| title | Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_full | Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_fullStr | Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_full_unstemmed | Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_short | Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_sort | arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| title_unstemmed | Arterial to end‐tidal carbon dioxide difference in children undergoing mechanical ventilation of the lungs during general anaesthesia |
| topic | Anesthesiology and Pain Medicine |
| url | http://dx.doi.org/10.1111/anae.13969 |