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Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients
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| Zeitschriftentitel: | Anaesthesia |
|---|---|
| Personen und Körperschaften: | , , , , , , |
| In: | Anaesthesia, 68, 2013, 7, S. 760-764 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
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| Schlagwörter: |
| author_facet |
O'Brien, C. Urquhart, C. S. Allam, S Anderson, K. J. Leitch, J. A. Macpherson, A. Kenny, G. N. C. O'Brien, C. Urquhart, C. S. Allam, S Anderson, K. J. Leitch, J. A. Macpherson, A. Kenny, G. N. C. |
|---|---|
| author |
O'Brien, C. Urquhart, C. S. Allam, S Anderson, K. J. Leitch, J. A. Macpherson, A. Kenny, G. N. C. |
| spellingShingle |
O'Brien, C. Urquhart, C. S. Allam, S Anderson, K. J. Leitch, J. A. Macpherson, A. Kenny, G. N. C. Anaesthesia Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients Anesthesiology and Pain Medicine |
| author_sort |
o'brien, c. |
| spelling |
O'Brien, C. Urquhart, C. S. Allam, S Anderson, K. J. Leitch, J. A. Macpherson, A. Kenny, G. N. C. 0003-2409 1365-2044 Wiley Anesthesiology and Pain Medicine http://dx.doi.org/10.1111/anae.12291 <jats:title>Summary</jats:title><jats:p>Previous volunteer studies of an effect‐site controlled patient‐maintained sedation system using propofol have demonstrated a risk of oversedation. We have incorporated a reaction time monitor into the handset to add an individualised patient‐feedback mechanism. This pilot study assessed if the reaction time‐feedback modification would prove safe and effective in 20 healthy patients receiving sedation while undergoing oral surgery. All patients successfully sedated themselves without reaching any unsafe endpoints. All 20 maintained verbal contact throughout. The mean (<jats:styled-content style="fixed-case">SD</jats:styled-content>) lowest peripheral blood oxygen saturation was 98.0 (2.1)% breathing room air. No patient required supplementary oxygen. The mean (<jats:styled-content style="fixed-case">SD</jats:styled-content>) maximum effect‐site propofol concentration reached was 1.6 (0.5) μg.ml<jats:sup>−1</jats:sup>. The present system was found to be safe and effective, allowing oral surgery treatment under conscious sedation, but preventing oversedation.</jats:p> Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients Anaesthesia |
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Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_unstemmed |
Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_full |
Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_fullStr |
Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_full_unstemmed |
Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_short |
Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_sort |
reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
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Anesthesiology and Pain Medicine |
| url |
http://dx.doi.org/10.1111/anae.12291 |
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2013 |
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760-764 |
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<jats:title>Summary</jats:title><jats:p>Previous volunteer studies of an effect‐site controlled patient‐maintained sedation system using propofol have demonstrated a risk of oversedation. We have incorporated a reaction time monitor into the handset to add an individualised patient‐feedback mechanism. This pilot study assessed if the reaction time‐feedback modification would prove safe and effective in 20 healthy patients receiving sedation while undergoing oral surgery. All patients successfully sedated themselves without reaching any unsafe endpoints. All 20 maintained verbal contact throughout. The mean (<jats:styled-content style="fixed-case">SD</jats:styled-content>) lowest peripheral blood oxygen saturation was 98.0 (2.1)% breathing room air. No patient required supplementary oxygen. The mean (<jats:styled-content style="fixed-case">SD</jats:styled-content>) maximum effect‐site propofol concentration reached was 1.6 (0.5) μg.ml<jats:sup>−1</jats:sup>. The present system was found to be safe and effective, allowing oral surgery treatment under conscious sedation, but preventing oversedation.</jats:p> |
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| author | O'Brien, C., Urquhart, C. S., Allam, S, Anderson, K. J., Leitch, J. A., Macpherson, A., Kenny, G. N. C. |
| author_facet | O'Brien, C., Urquhart, C. S., Allam, S, Anderson, K. J., Leitch, J. A., Macpherson, A., Kenny, G. N. C., O'Brien, C., Urquhart, C. S., Allam, S, Anderson, K. J., Leitch, J. A., Macpherson, A., Kenny, G. N. C. |
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| description | <jats:title>Summary</jats:title><jats:p>Previous volunteer studies of an effect‐site controlled patient‐maintained sedation system using propofol have demonstrated a risk of oversedation. We have incorporated a reaction time monitor into the handset to add an individualised patient‐feedback mechanism. This pilot study assessed if the reaction time‐feedback modification would prove safe and effective in 20 healthy patients receiving sedation while undergoing oral surgery. All patients successfully sedated themselves without reaching any unsafe endpoints. All 20 maintained verbal contact throughout. The mean (<jats:styled-content style="fixed-case">SD</jats:styled-content>) lowest peripheral blood oxygen saturation was 98.0 (2.1)% breathing room air. No patient required supplementary oxygen. The mean (<jats:styled-content style="fixed-case">SD</jats:styled-content>) maximum effect‐site propofol concentration reached was 1.6 (0.5) μg.ml<jats:sup>−1</jats:sup>. The present system was found to be safe and effective, allowing oral surgery treatment under conscious sedation, but preventing oversedation.</jats:p> |
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| spelling | O'Brien, C. Urquhart, C. S. Allam, S Anderson, K. J. Leitch, J. A. Macpherson, A. Kenny, G. N. C. 0003-2409 1365-2044 Wiley Anesthesiology and Pain Medicine http://dx.doi.org/10.1111/anae.12291 <jats:title>Summary</jats:title><jats:p>Previous volunteer studies of an effect‐site controlled patient‐maintained sedation system using propofol have demonstrated a risk of oversedation. We have incorporated a reaction time monitor into the handset to add an individualised patient‐feedback mechanism. This pilot study assessed if the reaction time‐feedback modification would prove safe and effective in 20 healthy patients receiving sedation while undergoing oral surgery. All patients successfully sedated themselves without reaching any unsafe endpoints. All 20 maintained verbal contact throughout. The mean (<jats:styled-content style="fixed-case">SD</jats:styled-content>) lowest peripheral blood oxygen saturation was 98.0 (2.1)% breathing room air. No patient required supplementary oxygen. The mean (<jats:styled-content style="fixed-case">SD</jats:styled-content>) maximum effect‐site propofol concentration reached was 1.6 (0.5) μg.ml<jats:sup>−1</jats:sup>. The present system was found to be safe and effective, allowing oral surgery treatment under conscious sedation, but preventing oversedation.</jats:p> Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients Anaesthesia |
| spellingShingle | O'Brien, C., Urquhart, C. S., Allam, S, Anderson, K. J., Leitch, J. A., Macpherson, A., Kenny, G. N. C., Anaesthesia, Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients, Anesthesiology and Pain Medicine |
| title | Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_full | Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_fullStr | Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_full_unstemmed | Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_short | Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_sort | reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| title_unstemmed | Reaction time‐monitored patient‐maintained propofol sedation: a pilot study in oral surgery patients |
| topic | Anesthesiology and Pain Medicine |
| url | http://dx.doi.org/10.1111/anae.12291 |