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Management of bronchiectasis in adults
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| Zeitschriftentitel: | European Respiratory Journal |
|---|---|
| Personen und Körperschaften: | , , |
| In: | European Respiratory Journal, 45, 2015, 5, S. 1446-1462 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
European Respiratory Society (ERS)
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Chalmers, James D. Aliberti, Stefano Blasi, Francesco Chalmers, James D. Aliberti, Stefano Blasi, Francesco |
|---|---|
| author |
Chalmers, James D. Aliberti, Stefano Blasi, Francesco |
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Chalmers, James D. Aliberti, Stefano Blasi, Francesco European Respiratory Journal Management of bronchiectasis in adults Pulmonary and Respiratory Medicine |
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chalmers, james d. |
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Chalmers, James D. Aliberti, Stefano Blasi, Francesco 0903-1936 1399-3003 European Respiratory Society (ERS) Pulmonary and Respiratory Medicine http://dx.doi.org/10.1183/09031936.00119114 <jats:p>Formerly regarded as a rare disease, bronchiectasis is now increasingly recognised and a renewed interest in the condition is stimulating drug development and clinical research. Bronchiectasis represents the final common pathway of a number of infectious, genetic, autoimmune, developmental and allergic disorders and is highly heterogeneous in its aetiology, impact and prognosis.</jats:p><jats:p>The goals of therapy should be: to improve airway mucus clearance through physiotherapy with or without adjunctive therapies; to suppress, eradicate and prevent airway bacterial colonisation; to reduce airway inflammation; and to improve physical functioning and quality of life.</jats:p><jats:p>Fortunately, an increasing body of evidence supports interventions in bronchiectasis. The field has benefited greatly from the introduction of evidence-based guidelines in some European countries and randomised controlled trials have now demonstrated the benefit of long-term macrolide therapy, with accumulating evidence for inhaled therapies, physiotherapy and pulmonary rehabilitation.</jats:p><jats:p>This review provides a critical update on the management of bronchiectasis focussing on emerging evidence and recent randomised controlled trials.</jats:p> Management of bronchiectasis in adults European Respiratory Journal |
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Management of bronchiectasis in adults |
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Management of bronchiectasis in adults |
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Management of bronchiectasis in adults |
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Management of bronchiectasis in adults |
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Management of bronchiectasis in adults |
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Management of bronchiectasis in adults |
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management of bronchiectasis in adults |
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Pulmonary and Respiratory Medicine |
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http://dx.doi.org/10.1183/09031936.00119114 |
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2015 |
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1446-1462 |
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<jats:p>Formerly regarded as a rare disease, bronchiectasis is now increasingly recognised and a renewed interest in the condition is stimulating drug development and clinical research. Bronchiectasis represents the final common pathway of a number of infectious, genetic, autoimmune, developmental and allergic disorders and is highly heterogeneous in its aetiology, impact and prognosis.</jats:p><jats:p>The goals of therapy should be: to improve airway mucus clearance through physiotherapy with or without adjunctive therapies; to suppress, eradicate and prevent airway bacterial colonisation; to reduce airway inflammation; and to improve physical functioning and quality of life.</jats:p><jats:p>Fortunately, an increasing body of evidence supports interventions in bronchiectasis. The field has benefited greatly from the introduction of evidence-based guidelines in some European countries and randomised controlled trials have now demonstrated the benefit of long-term macrolide therapy, with accumulating evidence for inhaled therapies, physiotherapy and pulmonary rehabilitation.</jats:p><jats:p>This review provides a critical update on the management of bronchiectasis focussing on emerging evidence and recent randomised controlled trials.</jats:p> |
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| author | Chalmers, James D., Aliberti, Stefano, Blasi, Francesco |
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| description | <jats:p>Formerly regarded as a rare disease, bronchiectasis is now increasingly recognised and a renewed interest in the condition is stimulating drug development and clinical research. Bronchiectasis represents the final common pathway of a number of infectious, genetic, autoimmune, developmental and allergic disorders and is highly heterogeneous in its aetiology, impact and prognosis.</jats:p><jats:p>The goals of therapy should be: to improve airway mucus clearance through physiotherapy with or without adjunctive therapies; to suppress, eradicate and prevent airway bacterial colonisation; to reduce airway inflammation; and to improve physical functioning and quality of life.</jats:p><jats:p>Fortunately, an increasing body of evidence supports interventions in bronchiectasis. The field has benefited greatly from the introduction of evidence-based guidelines in some European countries and randomised controlled trials have now demonstrated the benefit of long-term macrolide therapy, with accumulating evidence for inhaled therapies, physiotherapy and pulmonary rehabilitation.</jats:p><jats:p>This review provides a critical update on the management of bronchiectasis focussing on emerging evidence and recent randomised controlled trials.</jats:p> |
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| spelling | Chalmers, James D. Aliberti, Stefano Blasi, Francesco 0903-1936 1399-3003 European Respiratory Society (ERS) Pulmonary and Respiratory Medicine http://dx.doi.org/10.1183/09031936.00119114 <jats:p>Formerly regarded as a rare disease, bronchiectasis is now increasingly recognised and a renewed interest in the condition is stimulating drug development and clinical research. Bronchiectasis represents the final common pathway of a number of infectious, genetic, autoimmune, developmental and allergic disorders and is highly heterogeneous in its aetiology, impact and prognosis.</jats:p><jats:p>The goals of therapy should be: to improve airway mucus clearance through physiotherapy with or without adjunctive therapies; to suppress, eradicate and prevent airway bacterial colonisation; to reduce airway inflammation; and to improve physical functioning and quality of life.</jats:p><jats:p>Fortunately, an increasing body of evidence supports interventions in bronchiectasis. The field has benefited greatly from the introduction of evidence-based guidelines in some European countries and randomised controlled trials have now demonstrated the benefit of long-term macrolide therapy, with accumulating evidence for inhaled therapies, physiotherapy and pulmonary rehabilitation.</jats:p><jats:p>This review provides a critical update on the management of bronchiectasis focussing on emerging evidence and recent randomised controlled trials.</jats:p> Management of bronchiectasis in adults European Respiratory Journal |
| spellingShingle | Chalmers, James D., Aliberti, Stefano, Blasi, Francesco, European Respiratory Journal, Management of bronchiectasis in adults, Pulmonary and Respiratory Medicine |
| title | Management of bronchiectasis in adults |
| title_full | Management of bronchiectasis in adults |
| title_fullStr | Management of bronchiectasis in adults |
| title_full_unstemmed | Management of bronchiectasis in adults |
| title_short | Management of bronchiectasis in adults |
| title_sort | management of bronchiectasis in adults |
| title_unstemmed | Management of bronchiectasis in adults |
| topic | Pulmonary and Respiratory Medicine |
| url | http://dx.doi.org/10.1183/09031936.00119114 |