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Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia
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| Zeitschriftentitel: | Blood |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , , , , |
| In: | Blood, 121, 2013, 24, S. 4925-4929 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Society of Hematology
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| Schlagwörter: |
| author_facet |
Gandre-Babbe, Shilpa Paluru, Prasuna Aribeana, Chiaka Chou, Stella T. Bresolin, Silvia Lu, Lin Sullivan, Spencer K. Tasian, Sarah K. Weng, Julie Favre, Helene Choi, John K. French, Deborah L. Loh, Mignon L. Weiss, Mitchell J. Gandre-Babbe, Shilpa Paluru, Prasuna Aribeana, Chiaka Chou, Stella T. Bresolin, Silvia Lu, Lin Sullivan, Spencer K. Tasian, Sarah K. Weng, Julie Favre, Helene Choi, John K. French, Deborah L. Loh, Mignon L. Weiss, Mitchell J. |
|---|---|
| author |
Gandre-Babbe, Shilpa Paluru, Prasuna Aribeana, Chiaka Chou, Stella T. Bresolin, Silvia Lu, Lin Sullivan, Spencer K. Tasian, Sarah K. Weng, Julie Favre, Helene Choi, John K. French, Deborah L. Loh, Mignon L. Weiss, Mitchell J. |
| spellingShingle |
Gandre-Babbe, Shilpa Paluru, Prasuna Aribeana, Chiaka Chou, Stella T. Bresolin, Silvia Lu, Lin Sullivan, Spencer K. Tasian, Sarah K. Weng, Julie Favre, Helene Choi, John K. French, Deborah L. Loh, Mignon L. Weiss, Mitchell J. Blood Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia Cell Biology Hematology Immunology Biochemistry |
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gandre-babbe, shilpa |
| spelling |
Gandre-Babbe, Shilpa Paluru, Prasuna Aribeana, Chiaka Chou, Stella T. Bresolin, Silvia Lu, Lin Sullivan, Spencer K. Tasian, Sarah K. Weng, Julie Favre, Helene Choi, John K. French, Deborah L. Loh, Mignon L. Weiss, Mitchell J. 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2013-01-478412 <jats:title>Key Points</jats:title> <jats:p>Patient-derived iPSCs recapitulate juvenile myelomonocytic leukemia. MEK inhibition normalizes GM-CSF independence and hypersensitivity in myeloid precursors from JMML iPSCs.</jats:p> Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia Blood |
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10.1182/blood-2013-01-478412 |
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American Society of Hematology, 2013 |
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American Society of Hematology, 2013 |
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| title |
Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_unstemmed |
Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_full |
Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_fullStr |
Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_full_unstemmed |
Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_short |
Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_sort |
patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| topic |
Cell Biology Hematology Immunology Biochemistry |
| url |
http://dx.doi.org/10.1182/blood-2013-01-478412 |
| publishDate |
2013 |
| physical |
4925-4929 |
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<jats:title>Key Points</jats:title>
<jats:p>Patient-derived iPSCs recapitulate juvenile myelomonocytic leukemia. MEK inhibition normalizes GM-CSF independence and hypersensitivity in myeloid precursors from JMML iPSCs.</jats:p> |
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| author | Gandre-Babbe, Shilpa, Paluru, Prasuna, Aribeana, Chiaka, Chou, Stella T., Bresolin, Silvia, Lu, Lin, Sullivan, Spencer K., Tasian, Sarah K., Weng, Julie, Favre, Helene, Choi, John K., French, Deborah L., Loh, Mignon L., Weiss, Mitchell J. |
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| description | <jats:title>Key Points</jats:title> <jats:p>Patient-derived iPSCs recapitulate juvenile myelomonocytic leukemia. MEK inhibition normalizes GM-CSF independence and hypersensitivity in myeloid precursors from JMML iPSCs.</jats:p> |
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| spelling | Gandre-Babbe, Shilpa Paluru, Prasuna Aribeana, Chiaka Chou, Stella T. Bresolin, Silvia Lu, Lin Sullivan, Spencer K. Tasian, Sarah K. Weng, Julie Favre, Helene Choi, John K. French, Deborah L. Loh, Mignon L. Weiss, Mitchell J. 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2013-01-478412 <jats:title>Key Points</jats:title> <jats:p>Patient-derived iPSCs recapitulate juvenile myelomonocytic leukemia. MEK inhibition normalizes GM-CSF independence and hypersensitivity in myeloid precursors from JMML iPSCs.</jats:p> Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia Blood |
| spellingShingle | Gandre-Babbe, Shilpa, Paluru, Prasuna, Aribeana, Chiaka, Chou, Stella T., Bresolin, Silvia, Lu, Lin, Sullivan, Spencer K., Tasian, Sarah K., Weng, Julie, Favre, Helene, Choi, John K., French, Deborah L., Loh, Mignon L., Weiss, Mitchell J., Blood, Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia, Cell Biology, Hematology, Immunology, Biochemistry |
| title | Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_full | Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_fullStr | Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_full_unstemmed | Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_short | Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_sort | patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| title_unstemmed | Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia |
| topic | Cell Biology, Hematology, Immunology, Biochemistry |
| url | http://dx.doi.org/10.1182/blood-2013-01-478412 |