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The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
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Zeitschriftentitel: | Blood |
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Personen und Körperschaften: | , , , , , , , , |
In: | Blood, 123, 2014, 17, S. 2703-2714 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
American Society of Hematology
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Schlagwörter: |
author_facet |
Starnes, Taylor W. Bennin, David A. Bing, Xinyu Eickhoff, Jens C. Grahf, Daniel C. Bellak, Jason M. Seroogy, Christine M. Ferguson, Polly J. Huttenlocher, Anna Starnes, Taylor W. Bennin, David A. Bing, Xinyu Eickhoff, Jens C. Grahf, Daniel C. Bellak, Jason M. Seroogy, Christine M. Ferguson, Polly J. Huttenlocher, Anna |
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author |
Starnes, Taylor W. Bennin, David A. Bing, Xinyu Eickhoff, Jens C. Grahf, Daniel C. Bellak, Jason M. Seroogy, Christine M. Ferguson, Polly J. Huttenlocher, Anna |
spellingShingle |
Starnes, Taylor W. Bennin, David A. Bing, Xinyu Eickhoff, Jens C. Grahf, Daniel C. Bellak, Jason M. Seroogy, Christine M. Ferguson, Polly J. Huttenlocher, Anna Blood The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages Cell Biology Hematology Immunology Biochemistry |
author_sort |
starnes, taylor w. |
spelling |
Starnes, Taylor W. Bennin, David A. Bing, Xinyu Eickhoff, Jens C. Grahf, Daniel C. Bellak, Jason M. Seroogy, Christine M. Ferguson, Polly J. Huttenlocher, Anna 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2013-07-516948 <jats:title>Key Points</jats:title><jats:p>PSTPIP1 regulates the transition from podosomes to filopodia in macrophages by modulating WASP activity. The novel PSTPIP1-R405C mutant induces filopodia formation, increases matrix degradation, and is associated with severe pyoderma gangrenosum.</jats:p> The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages Blood |
doi_str_mv |
10.1182/blood-2013-07-516948 |
facet_avail |
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Biologie Medizin Chemie und Pharmazie |
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ElectronicArticle |
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imprint |
American Society of Hematology, 2014 |
imprint_str_mv |
American Society of Hematology, 2014 |
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0006-4971 1528-0020 |
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0006-4971 1528-0020 |
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English |
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2014 |
publisher |
American Society of Hematology |
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ai |
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series |
Blood |
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49 |
title |
The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_unstemmed |
The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_full |
The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_fullStr |
The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_full_unstemmed |
The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_short |
The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_sort |
the f-bar protein pstpip1 controls extracellular matrix degradation and filopodia formation in macrophages |
topic |
Cell Biology Hematology Immunology Biochemistry |
url |
http://dx.doi.org/10.1182/blood-2013-07-516948 |
publishDate |
2014 |
physical |
2703-2714 |
description |
<jats:title>Key Points</jats:title><jats:p>PSTPIP1 regulates the transition from podosomes to filopodia in macrophages by modulating WASP activity. The novel PSTPIP1-R405C mutant induces filopodia formation, increases matrix degradation, and is associated with severe pyoderma gangrenosum.</jats:p> |
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author | Starnes, Taylor W., Bennin, David A., Bing, Xinyu, Eickhoff, Jens C., Grahf, Daniel C., Bellak, Jason M., Seroogy, Christine M., Ferguson, Polly J., Huttenlocher, Anna |
author_facet | Starnes, Taylor W., Bennin, David A., Bing, Xinyu, Eickhoff, Jens C., Grahf, Daniel C., Bellak, Jason M., Seroogy, Christine M., Ferguson, Polly J., Huttenlocher, Anna, Starnes, Taylor W., Bennin, David A., Bing, Xinyu, Eickhoff, Jens C., Grahf, Daniel C., Bellak, Jason M., Seroogy, Christine M., Ferguson, Polly J., Huttenlocher, Anna |
author_sort | starnes, taylor w. |
container_issue | 17 |
container_start_page | 2703 |
container_title | Blood |
container_volume | 123 |
description | <jats:title>Key Points</jats:title><jats:p>PSTPIP1 regulates the transition from podosomes to filopodia in macrophages by modulating WASP activity. The novel PSTPIP1-R405C mutant induces filopodia formation, increases matrix degradation, and is associated with severe pyoderma gangrenosum.</jats:p> |
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imprint | American Society of Hematology, 2014 |
imprint_str_mv | American Society of Hematology, 2014 |
institution | DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229 |
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publishDate | 2014 |
publishDateSort | 2014 |
publisher | American Society of Hematology |
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recordtype | ai |
series | Blood |
source_id | 49 |
spelling | Starnes, Taylor W. Bennin, David A. Bing, Xinyu Eickhoff, Jens C. Grahf, Daniel C. Bellak, Jason M. Seroogy, Christine M. Ferguson, Polly J. Huttenlocher, Anna 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2013-07-516948 <jats:title>Key Points</jats:title><jats:p>PSTPIP1 regulates the transition from podosomes to filopodia in macrophages by modulating WASP activity. The novel PSTPIP1-R405C mutant induces filopodia formation, increases matrix degradation, and is associated with severe pyoderma gangrenosum.</jats:p> The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages Blood |
spellingShingle | Starnes, Taylor W., Bennin, David A., Bing, Xinyu, Eickhoff, Jens C., Grahf, Daniel C., Bellak, Jason M., Seroogy, Christine M., Ferguson, Polly J., Huttenlocher, Anna, Blood, The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages, Cell Biology, Hematology, Immunology, Biochemistry |
title | The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_full | The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_fullStr | The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_full_unstemmed | The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_short | The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_sort | the f-bar protein pstpip1 controls extracellular matrix degradation and filopodia formation in macrophages |
title_unstemmed | The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages |
topic | Cell Biology, Hematology, Immunology, Biochemistry |
url | http://dx.doi.org/10.1182/blood-2013-07-516948 |