author_facet Starnes, Taylor W.
Bennin, David A.
Bing, Xinyu
Eickhoff, Jens C.
Grahf, Daniel C.
Bellak, Jason M.
Seroogy, Christine M.
Ferguson, Polly J.
Huttenlocher, Anna
Starnes, Taylor W.
Bennin, David A.
Bing, Xinyu
Eickhoff, Jens C.
Grahf, Daniel C.
Bellak, Jason M.
Seroogy, Christine M.
Ferguson, Polly J.
Huttenlocher, Anna
author Starnes, Taylor W.
Bennin, David A.
Bing, Xinyu
Eickhoff, Jens C.
Grahf, Daniel C.
Bellak, Jason M.
Seroogy, Christine M.
Ferguson, Polly J.
Huttenlocher, Anna
spellingShingle Starnes, Taylor W.
Bennin, David A.
Bing, Xinyu
Eickhoff, Jens C.
Grahf, Daniel C.
Bellak, Jason M.
Seroogy, Christine M.
Ferguson, Polly J.
Huttenlocher, Anna
Blood
The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
Cell Biology
Hematology
Immunology
Biochemistry
author_sort starnes, taylor w.
spelling Starnes, Taylor W. Bennin, David A. Bing, Xinyu Eickhoff, Jens C. Grahf, Daniel C. Bellak, Jason M. Seroogy, Christine M. Ferguson, Polly J. Huttenlocher, Anna 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2013-07-516948 <jats:title>Key Points</jats:title><jats:p>PSTPIP1 regulates the transition from podosomes to filopodia in macrophages by modulating WASP activity. The novel PSTPIP1-R405C mutant induces filopodia formation, increases matrix degradation, and is associated with severe pyoderma gangrenosum.</jats:p> The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages Blood
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title The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
title_unstemmed The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
title_full The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
title_fullStr The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
title_full_unstemmed The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
title_short The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
title_sort the f-bar protein pstpip1 controls extracellular matrix degradation and filopodia formation in macrophages
topic Cell Biology
Hematology
Immunology
Biochemistry
url http://dx.doi.org/10.1182/blood-2013-07-516948
publishDate 2014
physical 2703-2714
description <jats:title>Key Points</jats:title><jats:p>PSTPIP1 regulates the transition from podosomes to filopodia in macrophages by modulating WASP activity. The novel PSTPIP1-R405C mutant induces filopodia formation, increases matrix degradation, and is associated with severe pyoderma gangrenosum.</jats:p>
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author Starnes, Taylor W., Bennin, David A., Bing, Xinyu, Eickhoff, Jens C., Grahf, Daniel C., Bellak, Jason M., Seroogy, Christine M., Ferguson, Polly J., Huttenlocher, Anna
author_facet Starnes, Taylor W., Bennin, David A., Bing, Xinyu, Eickhoff, Jens C., Grahf, Daniel C., Bellak, Jason M., Seroogy, Christine M., Ferguson, Polly J., Huttenlocher, Anna, Starnes, Taylor W., Bennin, David A., Bing, Xinyu, Eickhoff, Jens C., Grahf, Daniel C., Bellak, Jason M., Seroogy, Christine M., Ferguson, Polly J., Huttenlocher, Anna
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description <jats:title>Key Points</jats:title><jats:p>PSTPIP1 regulates the transition from podosomes to filopodia in macrophages by modulating WASP activity. The novel PSTPIP1-R405C mutant induces filopodia formation, increases matrix degradation, and is associated with severe pyoderma gangrenosum.</jats:p>
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spelling Starnes, Taylor W. Bennin, David A. Bing, Xinyu Eickhoff, Jens C. Grahf, Daniel C. Bellak, Jason M. Seroogy, Christine M. Ferguson, Polly J. Huttenlocher, Anna 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2013-07-516948 <jats:title>Key Points</jats:title><jats:p>PSTPIP1 regulates the transition from podosomes to filopodia in macrophages by modulating WASP activity. The novel PSTPIP1-R405C mutant induces filopodia formation, increases matrix degradation, and is associated with severe pyoderma gangrenosum.</jats:p> The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages Blood
spellingShingle Starnes, Taylor W., Bennin, David A., Bing, Xinyu, Eickhoff, Jens C., Grahf, Daniel C., Bellak, Jason M., Seroogy, Christine M., Ferguson, Polly J., Huttenlocher, Anna, Blood, The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages, Cell Biology, Hematology, Immunology, Biochemistry
title The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
title_full The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
title_fullStr The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
title_full_unstemmed The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
title_short The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
title_sort the f-bar protein pstpip1 controls extracellular matrix degradation and filopodia formation in macrophages
title_unstemmed The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages
topic Cell Biology, Hematology, Immunology, Biochemistry
url http://dx.doi.org/10.1182/blood-2013-07-516948