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How I manage medical complications of β-thalassemia in adults
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Zeitschriftentitel: | Blood |
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Personen und Körperschaften: | , |
In: | Blood, 132, 2018, 17, S. 1781-1791 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
American Society of Hematology
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Schlagwörter: |
author_facet |
Taher, Ali T. Cappellini, Maria Domenica Taher, Ali T. Cappellini, Maria Domenica |
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author |
Taher, Ali T. Cappellini, Maria Domenica |
spellingShingle |
Taher, Ali T. Cappellini, Maria Domenica Blood How I manage medical complications of β-thalassemia in adults Cell Biology Hematology Immunology Biochemistry |
author_sort |
taher, ali t. |
spelling |
Taher, Ali T. Cappellini, Maria Domenica 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2018-06-818187 <jats:title>Abstract</jats:title> <jats:p>The complex pathophysiology in β-thalassemia can translate to multiple morbidities that affect every organ system. Improved survival due to advances in management means that patients are exposed to the harmful effects of ineffective erythropoiesis, anemia, and iron overload for a longer duration, and we started seeing new or more frequent complications in adult compared with younger patients. In this article, we highlight particular aspects of managing adult patients with β-thalassemia, using our own experience in treating such patients. We cover both transfusion-dependent and nontransfusion-dependent forms of the disease and tackle specific morbidities of highest interest.</jats:p> How I manage medical complications of β-thalassemia in adults Blood |
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10.1182/blood-2018-06-818187 |
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American Society of Hematology, 2018 |
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American Society of Hematology, 2018 |
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American Society of Hematology |
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title |
How I manage medical complications of β-thalassemia in adults |
title_unstemmed |
How I manage medical complications of β-thalassemia in adults |
title_full |
How I manage medical complications of β-thalassemia in adults |
title_fullStr |
How I manage medical complications of β-thalassemia in adults |
title_full_unstemmed |
How I manage medical complications of β-thalassemia in adults |
title_short |
How I manage medical complications of β-thalassemia in adults |
title_sort |
how i manage medical complications of β-thalassemia in adults |
topic |
Cell Biology Hematology Immunology Biochemistry |
url |
http://dx.doi.org/10.1182/blood-2018-06-818187 |
publishDate |
2018 |
physical |
1781-1791 |
description |
<jats:title>Abstract</jats:title>
<jats:p>The complex pathophysiology in β-thalassemia can translate to multiple morbidities that affect every organ system. Improved survival due to advances in management means that patients are exposed to the harmful effects of ineffective erythropoiesis, anemia, and iron overload for a longer duration, and we started seeing new or more frequent complications in adult compared with younger patients. In this article, we highlight particular aspects of managing adult patients with β-thalassemia, using our own experience in treating such patients. We cover both transfusion-dependent and nontransfusion-dependent forms of the disease and tackle specific morbidities of highest interest.</jats:p> |
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author | Taher, Ali T., Cappellini, Maria Domenica |
author_facet | Taher, Ali T., Cappellini, Maria Domenica, Taher, Ali T., Cappellini, Maria Domenica |
author_sort | taher, ali t. |
container_issue | 17 |
container_start_page | 1781 |
container_title | Blood |
container_volume | 132 |
description | <jats:title>Abstract</jats:title> <jats:p>The complex pathophysiology in β-thalassemia can translate to multiple morbidities that affect every organ system. Improved survival due to advances in management means that patients are exposed to the harmful effects of ineffective erythropoiesis, anemia, and iron overload for a longer duration, and we started seeing new or more frequent complications in adult compared with younger patients. In this article, we highlight particular aspects of managing adult patients with β-thalassemia, using our own experience in treating such patients. We cover both transfusion-dependent and nontransfusion-dependent forms of the disease and tackle specific morbidities of highest interest.</jats:p> |
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spelling | Taher, Ali T. Cappellini, Maria Domenica 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2018-06-818187 <jats:title>Abstract</jats:title> <jats:p>The complex pathophysiology in β-thalassemia can translate to multiple morbidities that affect every organ system. Improved survival due to advances in management means that patients are exposed to the harmful effects of ineffective erythropoiesis, anemia, and iron overload for a longer duration, and we started seeing new or more frequent complications in adult compared with younger patients. In this article, we highlight particular aspects of managing adult patients with β-thalassemia, using our own experience in treating such patients. We cover both transfusion-dependent and nontransfusion-dependent forms of the disease and tackle specific morbidities of highest interest.</jats:p> How I manage medical complications of β-thalassemia in adults Blood |
spellingShingle | Taher, Ali T., Cappellini, Maria Domenica, Blood, How I manage medical complications of β-thalassemia in adults, Cell Biology, Hematology, Immunology, Biochemistry |
title | How I manage medical complications of β-thalassemia in adults |
title_full | How I manage medical complications of β-thalassemia in adults |
title_fullStr | How I manage medical complications of β-thalassemia in adults |
title_full_unstemmed | How I manage medical complications of β-thalassemia in adults |
title_short | How I manage medical complications of β-thalassemia in adults |
title_sort | how i manage medical complications of β-thalassemia in adults |
title_unstemmed | How I manage medical complications of β-thalassemia in adults |
topic | Cell Biology, Hematology, Immunology, Biochemistry |
url | http://dx.doi.org/10.1182/blood-2018-06-818187 |