High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology

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Bibliographische Detailangaben
Zeitschriftentitel:	Blood
Personen und Körperschaften:	Scott, David W., King, Rebecca L., Staiger, Annette M., Ben-Neriah, Susana, Jiang, Aixiang, Horn, Heike, Mottok, Anja, Farinha, Pedro, Slack, Graham W., Ennishi, Daisuke, Schmitz, Norbert, Pfreundschuh, Michael, Nowakowski, Grzegorz S., Kahl, Brad S., Connors, Joseph M., Gascoyne, Randy D., Ott, German, Macon, William R., Rosenwald, Andreas
In:	Blood, 131, 2018, 18, S. 2060-2064
Format:	E-Article
Sprache:	Englisch
veröffentlicht:	American Society of Hematology
Schlagwörter:	Cell Biology Hematology Immunology Biochemistry

Details
Zusammenfassung:	<jats:title>Key Points</jats:title> <jats:p>HGBL-DH/TH makes up 8% of de novo DLBCL, with HGBL-DH/TH with BCL2 rearrangement being a GCB phenomenon. Restricting FISH testing to tumors with dual protein expression and GCB subtype results in testing <15% of tumors, but missing ∼35% of HGBL-DH/TH.</jats:p>
Umfang:	2060-2064
ISSN:	0006-4971 1528-0020
DOI:	10.1182/blood-2017-12-820605