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SETD1A protects HSCs from activation-induced functional decline in vivo
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| Zeitschriftentitel: | Blood |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , |
| In: | Blood, 131, 2018, 12, S. 1311-1324 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Society of Hematology
|
| Schlagwörter: |
| author_facet |
Arndt, Kathrin Kranz, Andrea Fohgrub, Juliane Jolly, Adrien Bledau, Anita S. Di Virgilio, Michela Lesche, Mathias Dahl, Andreas Höfer, Thomas Stewart, A. Francis Waskow, Claudia Arndt, Kathrin Kranz, Andrea Fohgrub, Juliane Jolly, Adrien Bledau, Anita S. Di Virgilio, Michela Lesche, Mathias Dahl, Andreas Höfer, Thomas Stewart, A. Francis Waskow, Claudia |
|---|---|
| author |
Arndt, Kathrin Kranz, Andrea Fohgrub, Juliane Jolly, Adrien Bledau, Anita S. Di Virgilio, Michela Lesche, Mathias Dahl, Andreas Höfer, Thomas Stewart, A. Francis Waskow, Claudia |
| spellingShingle |
Arndt, Kathrin Kranz, Andrea Fohgrub, Juliane Jolly, Adrien Bledau, Anita S. Di Virgilio, Michela Lesche, Mathias Dahl, Andreas Höfer, Thomas Stewart, A. Francis Waskow, Claudia Blood SETD1A protects HSCs from activation-induced functional decline in vivo Cell Biology Hematology Immunology Biochemistry |
| author_sort |
arndt, kathrin |
| spelling |
Arndt, Kathrin Kranz, Andrea Fohgrub, Juliane Jolly, Adrien Bledau, Anita S. Di Virgilio, Michela Lesche, Mathias Dahl, Andreas Höfer, Thomas Stewart, A. Francis Waskow, Claudia 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2017-09-806844 <jats:title>Key Points</jats:title> <jats:p>SETD1A regulates DNA damage signaling and repair in HSCs and hematopoietic precursors in the absence of reactive oxygen species accumulation. SETD1A is important for the survival of mice after inflammation-induced HSC activation in situ.</jats:p> SETD1A protects HSCs from activation-induced functional decline in vivo Blood |
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10.1182/blood-2017-09-806844 |
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American Society of Hematology, 2018 |
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American Society of Hematology, 2018 |
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| title |
SETD1A protects HSCs from activation-induced functional decline in vivo |
| title_unstemmed |
SETD1A protects HSCs from activation-induced functional decline in vivo |
| title_full |
SETD1A protects HSCs from activation-induced functional decline in vivo |
| title_fullStr |
SETD1A protects HSCs from activation-induced functional decline in vivo |
| title_full_unstemmed |
SETD1A protects HSCs from activation-induced functional decline in vivo |
| title_short |
SETD1A protects HSCs from activation-induced functional decline in vivo |
| title_sort |
setd1a protects hscs from activation-induced functional decline in vivo |
| topic |
Cell Biology Hematology Immunology Biochemistry |
| url |
http://dx.doi.org/10.1182/blood-2017-09-806844 |
| publishDate |
2018 |
| physical |
1311-1324 |
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<jats:title>Key Points</jats:title>
<jats:p>SETD1A regulates DNA damage signaling and repair in HSCs and hematopoietic precursors in the absence of reactive oxygen species accumulation. SETD1A is important for the survival of mice after inflammation-induced HSC activation in situ.</jats:p> |
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| author | Arndt, Kathrin, Kranz, Andrea, Fohgrub, Juliane, Jolly, Adrien, Bledau, Anita S., Di Virgilio, Michela, Lesche, Mathias, Dahl, Andreas, Höfer, Thomas, Stewart, A. Francis, Waskow, Claudia |
| author_facet | Arndt, Kathrin, Kranz, Andrea, Fohgrub, Juliane, Jolly, Adrien, Bledau, Anita S., Di Virgilio, Michela, Lesche, Mathias, Dahl, Andreas, Höfer, Thomas, Stewart, A. Francis, Waskow, Claudia, Arndt, Kathrin, Kranz, Andrea, Fohgrub, Juliane, Jolly, Adrien, Bledau, Anita S., Di Virgilio, Michela, Lesche, Mathias, Dahl, Andreas, Höfer, Thomas, Stewart, A. Francis, Waskow, Claudia |
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| description | <jats:title>Key Points</jats:title> <jats:p>SETD1A regulates DNA damage signaling and repair in HSCs and hematopoietic precursors in the absence of reactive oxygen species accumulation. SETD1A is important for the survival of mice after inflammation-induced HSC activation in situ.</jats:p> |
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| physical | 1311-1324 |
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| source_id | 49 |
| spelling | Arndt, Kathrin Kranz, Andrea Fohgrub, Juliane Jolly, Adrien Bledau, Anita S. Di Virgilio, Michela Lesche, Mathias Dahl, Andreas Höfer, Thomas Stewart, A. Francis Waskow, Claudia 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2017-09-806844 <jats:title>Key Points</jats:title> <jats:p>SETD1A regulates DNA damage signaling and repair in HSCs and hematopoietic precursors in the absence of reactive oxygen species accumulation. SETD1A is important for the survival of mice after inflammation-induced HSC activation in situ.</jats:p> SETD1A protects HSCs from activation-induced functional decline in vivo Blood |
| spellingShingle | Arndt, Kathrin, Kranz, Andrea, Fohgrub, Juliane, Jolly, Adrien, Bledau, Anita S., Di Virgilio, Michela, Lesche, Mathias, Dahl, Andreas, Höfer, Thomas, Stewart, A. Francis, Waskow, Claudia, Blood, SETD1A protects HSCs from activation-induced functional decline in vivo, Cell Biology, Hematology, Immunology, Biochemistry |
| title | SETD1A protects HSCs from activation-induced functional decline in vivo |
| title_full | SETD1A protects HSCs from activation-induced functional decline in vivo |
| title_fullStr | SETD1A protects HSCs from activation-induced functional decline in vivo |
| title_full_unstemmed | SETD1A protects HSCs from activation-induced functional decline in vivo |
| title_short | SETD1A protects HSCs from activation-induced functional decline in vivo |
| title_sort | setd1a protects hscs from activation-induced functional decline in vivo |
| title_unstemmed | SETD1A protects HSCs from activation-induced functional decline in vivo |
| topic | Cell Biology, Hematology, Immunology, Biochemistry |
| url | http://dx.doi.org/10.1182/blood-2017-09-806844 |