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Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib
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Zeitschriftentitel: | Blood |
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Personen und Körperschaften: | , , , , , , , , , , , , , , , |
In: | Blood, 125, 2015, 16, S. 2497-2506 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
American Society of Hematology
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Schlagwörter: |
author_facet |
Byrd, John C. Furman, Richard R. Coutre, Steven E. Burger, Jan A. Blum, Kristie A. Coleman, Morton Wierda, William G. Jones, Jeffrey A. Zhao, Weiqiang Heerema, Nyla A. Johnson, Amy J. Shaw, Yun Bilotti, Elizabeth Zhou, Cathy James, Danelle F. O'Brien, Susan Byrd, John C. Furman, Richard R. Coutre, Steven E. Burger, Jan A. Blum, Kristie A. Coleman, Morton Wierda, William G. Jones, Jeffrey A. Zhao, Weiqiang Heerema, Nyla A. Johnson, Amy J. Shaw, Yun Bilotti, Elizabeth Zhou, Cathy James, Danelle F. O'Brien, Susan |
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author |
Byrd, John C. Furman, Richard R. Coutre, Steven E. Burger, Jan A. Blum, Kristie A. Coleman, Morton Wierda, William G. Jones, Jeffrey A. Zhao, Weiqiang Heerema, Nyla A. Johnson, Amy J. Shaw, Yun Bilotti, Elizabeth Zhou, Cathy James, Danelle F. O'Brien, Susan |
spellingShingle |
Byrd, John C. Furman, Richard R. Coutre, Steven E. Burger, Jan A. Blum, Kristie A. Coleman, Morton Wierda, William G. Jones, Jeffrey A. Zhao, Weiqiang Heerema, Nyla A. Johnson, Amy J. Shaw, Yun Bilotti, Elizabeth Zhou, Cathy James, Danelle F. O'Brien, Susan Blood Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib Cell Biology Hematology Immunology Biochemistry |
author_sort |
byrd, john c. |
spelling |
Byrd, John C. Furman, Richard R. Coutre, Steven E. Burger, Jan A. Blum, Kristie A. Coleman, Morton Wierda, William G. Jones, Jeffrey A. Zhao, Weiqiang Heerema, Nyla A. Johnson, Amy J. Shaw, Yun Bilotti, Elizabeth Zhou, Cathy James, Danelle F. O'Brien, Susan 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2014-10-606038 <jats:title>Key Points</jats:title> <jats:p>Three-year follow-up of ibrutinib in CLL demonstrated continued activity with durable responses that improve in quality with extended treatment. Toxicity diminished over time with respect to grade ≥3 cytopenias, fatigue, infections, and adverse events leading to discontinuation.</jats:p> Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib Blood |
doi_str_mv |
10.1182/blood-2014-10-606038 |
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Biologie Medizin Chemie und Pharmazie |
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American Society of Hematology, 2015 |
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American Society of Hematology, 2015 |
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2015 |
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American Society of Hematology |
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Blood |
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49 |
title |
Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
title_unstemmed |
Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
title_full |
Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
title_fullStr |
Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
title_full_unstemmed |
Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
title_short |
Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
title_sort |
three-year follow-up of treatment-naïve and previously treated patients with cll and sll receiving single-agent ibrutinib |
topic |
Cell Biology Hematology Immunology Biochemistry |
url |
http://dx.doi.org/10.1182/blood-2014-10-606038 |
publishDate |
2015 |
physical |
2497-2506 |
description |
<jats:title>Key Points</jats:title>
<jats:p>Three-year follow-up of ibrutinib in CLL demonstrated continued activity with durable responses that improve in quality with extended treatment. Toxicity diminished over time with respect to grade ≥3 cytopenias, fatigue, infections, and adverse events leading to discontinuation.</jats:p> |
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author | Byrd, John C., Furman, Richard R., Coutre, Steven E., Burger, Jan A., Blum, Kristie A., Coleman, Morton, Wierda, William G., Jones, Jeffrey A., Zhao, Weiqiang, Heerema, Nyla A., Johnson, Amy J., Shaw, Yun, Bilotti, Elizabeth, Zhou, Cathy, James, Danelle F., O'Brien, Susan |
author_facet | Byrd, John C., Furman, Richard R., Coutre, Steven E., Burger, Jan A., Blum, Kristie A., Coleman, Morton, Wierda, William G., Jones, Jeffrey A., Zhao, Weiqiang, Heerema, Nyla A., Johnson, Amy J., Shaw, Yun, Bilotti, Elizabeth, Zhou, Cathy, James, Danelle F., O'Brien, Susan, Byrd, John C., Furman, Richard R., Coutre, Steven E., Burger, Jan A., Blum, Kristie A., Coleman, Morton, Wierda, William G., Jones, Jeffrey A., Zhao, Weiqiang, Heerema, Nyla A., Johnson, Amy J., Shaw, Yun, Bilotti, Elizabeth, Zhou, Cathy, James, Danelle F., O'Brien, Susan |
author_sort | byrd, john c. |
container_issue | 16 |
container_start_page | 2497 |
container_title | Blood |
container_volume | 125 |
description | <jats:title>Key Points</jats:title> <jats:p>Three-year follow-up of ibrutinib in CLL demonstrated continued activity with durable responses that improve in quality with extended treatment. Toxicity diminished over time with respect to grade ≥3 cytopenias, fatigue, infections, and adverse events leading to discontinuation.</jats:p> |
doi_str_mv | 10.1182/blood-2014-10-606038 |
facet_avail | Online, Free |
finc_class_facet | Biologie, Medizin, Chemie und Pharmazie |
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publisher | American Society of Hematology |
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source_id | 49 |
spelling | Byrd, John C. Furman, Richard R. Coutre, Steven E. Burger, Jan A. Blum, Kristie A. Coleman, Morton Wierda, William G. Jones, Jeffrey A. Zhao, Weiqiang Heerema, Nyla A. Johnson, Amy J. Shaw, Yun Bilotti, Elizabeth Zhou, Cathy James, Danelle F. O'Brien, Susan 0006-4971 1528-0020 American Society of Hematology Cell Biology Hematology Immunology Biochemistry http://dx.doi.org/10.1182/blood-2014-10-606038 <jats:title>Key Points</jats:title> <jats:p>Three-year follow-up of ibrutinib in CLL demonstrated continued activity with durable responses that improve in quality with extended treatment. Toxicity diminished over time with respect to grade ≥3 cytopenias, fatigue, infections, and adverse events leading to discontinuation.</jats:p> Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib Blood |
spellingShingle | Byrd, John C., Furman, Richard R., Coutre, Steven E., Burger, Jan A., Blum, Kristie A., Coleman, Morton, Wierda, William G., Jones, Jeffrey A., Zhao, Weiqiang, Heerema, Nyla A., Johnson, Amy J., Shaw, Yun, Bilotti, Elizabeth, Zhou, Cathy, James, Danelle F., O'Brien, Susan, Blood, Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib, Cell Biology, Hematology, Immunology, Biochemistry |
title | Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
title_full | Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
title_fullStr | Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
title_full_unstemmed | Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
title_short | Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
title_sort | three-year follow-up of treatment-naïve and previously treated patients with cll and sll receiving single-agent ibrutinib |
title_unstemmed | Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib |
topic | Cell Biology, Hematology, Immunology, Biochemistry |
url | http://dx.doi.org/10.1182/blood-2014-10-606038 |