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Expression of transforming growth factor beta 1 in the submandibular gland of the rat.
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Zeitschriftentitel: | Journal of Histochemistry & Cytochemistry |
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Personen und Körperschaften: | , , , |
In: | Journal of Histochemistry & Cytochemistry, 39, 1991, 12, S. 1707-1711 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
SAGE Publications
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Schlagwörter: |
author_facet |
Amano, O Tsuji, T Nakamura, T Iseki, S Amano, O Tsuji, T Nakamura, T Iseki, S |
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author |
Amano, O Tsuji, T Nakamura, T Iseki, S |
spellingShingle |
Amano, O Tsuji, T Nakamura, T Iseki, S Journal of Histochemistry & Cytochemistry Expression of transforming growth factor beta 1 in the submandibular gland of the rat. Histology Anatomy |
author_sort |
amano, o |
spelling |
Amano, O Tsuji, T Nakamura, T Iseki, S 0022-1554 1551-5044 SAGE Publications Histology Anatomy http://dx.doi.org/10.1177/39.12.1940322 <jats:p> We employed immunocytochemical and in situ hybridization techniques to study the expression of transforming growth factor beta 1 (TGF-beta 1) in rat submandibular gland. Immunoreactivity for TGF-beta 1 was observed in the cells of granular convoluted tubules (GCTs), striated ducts, and excretory ducts, whereas it was absent in the intercalated ducts and secretory acini in both male and female rats. Immunoelectron microscopy revealed the ultrastructural localization of TGF-beta 1 in the secretory granules of GCT cells. On the other hand, signals for rat TGF-beta 1 mRNA were abundant in the GCT and striated duct cells but were lacking in the excretory duct cells. These results provided evidence for the production of TGF-beta 1 in the GCTs and striated ducts of rat submandibular gland. </jats:p> Expression of transforming growth factor beta 1 in the submandibular gland of the rat. Journal of Histochemistry & Cytochemistry |
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10.1177/39.12.1940322 |
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SAGE Publications, 1991 |
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SAGE Publications, 1991 |
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1991 |
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SAGE Publications |
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Journal of Histochemistry & Cytochemistry |
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title |
Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_unstemmed |
Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_full |
Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_fullStr |
Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_full_unstemmed |
Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_short |
Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_sort |
expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
topic |
Histology Anatomy |
url |
http://dx.doi.org/10.1177/39.12.1940322 |
publishDate |
1991 |
physical |
1707-1711 |
description |
<jats:p> We employed immunocytochemical and in situ hybridization techniques to study the expression of transforming growth factor beta 1 (TGF-beta 1) in rat submandibular gland. Immunoreactivity for TGF-beta 1 was observed in the cells of granular convoluted tubules (GCTs), striated ducts, and excretory ducts, whereas it was absent in the intercalated ducts and secretory acini in both male and female rats. Immunoelectron microscopy revealed the ultrastructural localization of TGF-beta 1 in the secretory granules of GCT cells. On the other hand, signals for rat TGF-beta 1 mRNA were abundant in the GCT and striated duct cells but were lacking in the excretory duct cells. These results provided evidence for the production of TGF-beta 1 in the GCTs and striated ducts of rat submandibular gland. </jats:p> |
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author | Amano, O, Tsuji, T, Nakamura, T, Iseki, S |
author_facet | Amano, O, Tsuji, T, Nakamura, T, Iseki, S, Amano, O, Tsuji, T, Nakamura, T, Iseki, S |
author_sort | amano, o |
container_issue | 12 |
container_start_page | 1707 |
container_title | Journal of Histochemistry & Cytochemistry |
container_volume | 39 |
description | <jats:p> We employed immunocytochemical and in situ hybridization techniques to study the expression of transforming growth factor beta 1 (TGF-beta 1) in rat submandibular gland. Immunoreactivity for TGF-beta 1 was observed in the cells of granular convoluted tubules (GCTs), striated ducts, and excretory ducts, whereas it was absent in the intercalated ducts and secretory acini in both male and female rats. Immunoelectron microscopy revealed the ultrastructural localization of TGF-beta 1 in the secretory granules of GCT cells. On the other hand, signals for rat TGF-beta 1 mRNA were abundant in the GCT and striated duct cells but were lacking in the excretory duct cells. These results provided evidence for the production of TGF-beta 1 in the GCTs and striated ducts of rat submandibular gland. </jats:p> |
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imprint | SAGE Publications, 1991 |
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institution | DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Zwi2, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229 |
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spelling | Amano, O Tsuji, T Nakamura, T Iseki, S 0022-1554 1551-5044 SAGE Publications Histology Anatomy http://dx.doi.org/10.1177/39.12.1940322 <jats:p> We employed immunocytochemical and in situ hybridization techniques to study the expression of transforming growth factor beta 1 (TGF-beta 1) in rat submandibular gland. Immunoreactivity for TGF-beta 1 was observed in the cells of granular convoluted tubules (GCTs), striated ducts, and excretory ducts, whereas it was absent in the intercalated ducts and secretory acini in both male and female rats. Immunoelectron microscopy revealed the ultrastructural localization of TGF-beta 1 in the secretory granules of GCT cells. On the other hand, signals for rat TGF-beta 1 mRNA were abundant in the GCT and striated duct cells but were lacking in the excretory duct cells. These results provided evidence for the production of TGF-beta 1 in the GCTs and striated ducts of rat submandibular gland. </jats:p> Expression of transforming growth factor beta 1 in the submandibular gland of the rat. Journal of Histochemistry & Cytochemistry |
spellingShingle | Amano, O, Tsuji, T, Nakamura, T, Iseki, S, Journal of Histochemistry & Cytochemistry, Expression of transforming growth factor beta 1 in the submandibular gland of the rat., Histology, Anatomy |
title | Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_full | Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_fullStr | Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_full_unstemmed | Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_short | Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_sort | expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
title_unstemmed | Expression of transforming growth factor beta 1 in the submandibular gland of the rat. |
topic | Histology, Anatomy |
url | http://dx.doi.org/10.1177/39.12.1940322 |