Wilson’s disease presenting during pregnancy: A diagnostic and therapeutic dilemma

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Bibliographische Detailangaben
Zeitschriftentitel:	Obstetric Medicine
Personen und Körperschaften:	Durairaj, Jayalakshmi, Shanbhag, Esha R, Veena, P, Gowda, Mamtha, Keepanasseril, Anish
In:	Obstetric Medicine, 11, 2018, 3, S. 148-150
Format:	E-Article
Sprache:	Englisch
veröffentlicht:	SAGE Publications
Schlagwörter:	Obstetrics and Gynecology

Details
Zusammenfassung:	<jats:p> Wilson’s disease is an autosomal recessive genetic disorder affecting copper transport leading to hepatic and/or neuropsychiatric manifestations. Changes in pregnancy can mimic certain clinical features of chronic liver disease such as spider naevi, and constraints for the use of various investigation for diagnosis pose a challenge to physicians. A high index of suspicion, multi-disciplinary team approach, use of correct non-invasive testing including viral serology, autoantibodies and copper studies and ultrasonography help to diagnose most of the pre-existing, de novo or pregnancy-specific hepatological conditions. We report a case of Wilson’s disease diagnosed during pregnancy and discuss the challenges in diagnosis and treatment in pregnancy. </jats:p>
Umfang:	148-150
ISSN:	1753-495X 1753-4968
DOI:	10.1177/1753495x17743162