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Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia?: Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease...
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Zeitschriftentitel: | American Journal of Alzheimer's Disease & Other Dementiasr |
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Personen und Körperschaften: | , , , , , , |
In: | American Journal of Alzheimer's Disease & Other Dementiasr, 28, 2013, 1, S. 62-68 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
SAGE Publications
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author_facet |
Aras, Sevgi Tek, Ibrahim Varli, Murat Yalcin, Ahmet Cengiz, Ozlem Karaarslan Atmis, Volkan Atli, Teslime Aras, Sevgi Tek, Ibrahim Varli, Murat Yalcin, Ahmet Cengiz, Ozlem Karaarslan Atmis, Volkan Atli, Teslime |
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author |
Aras, Sevgi Tek, Ibrahim Varli, Murat Yalcin, Ahmet Cengiz, Ozlem Karaarslan Atmis, Volkan Atli, Teslime |
spellingShingle |
Aras, Sevgi Tek, Ibrahim Varli, Murat Yalcin, Ahmet Cengiz, Ozlem Karaarslan Atmis, Volkan Atli, Teslime American Journal of Alzheimer's Disease & Other Dementiasr Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? Psychiatry and Mental health Geriatrics and Gerontology Clinical Psychology General Neuroscience |
author_sort |
aras, sevgi |
spelling |
Aras, Sevgi Tek, Ibrahim Varli, Murat Yalcin, Ahmet Cengiz, Ozlem Karaarslan Atmis, Volkan Atli, Teslime 1533-3175 1938-2731 SAGE Publications Psychiatry and Mental health Geriatrics and Gerontology Clinical Psychology General Neuroscience http://dx.doi.org/10.1177/1533317512467682 <jats:p> In this study, the importance of plasma viscosity (PV) as a biomarker in differential diagnosis of dementia subtypes especially Alzheimer’s disease (AD) and vascular dementia (VaD) was investigated. Our study recruited 45 patients with AD, 35 patients with VaD, and control participants. Individuals with inflammatory disease, infection, heart, liver, renal failure, and with high erythrocyte sedimentation rate and C-reactive protein levels were excluded from the study. The cases underwent comprehensive geriatric assessment. The PV measurements were performed with Brookfield DV-II viscometer. The PV measurements of AD, VaD, and control groups were 1.61 ± 0.08, 1.70 ± 0.06, and 1.48 ± 0.06 mPa S, respectively. The PV levels of the dementia group were significantly higher than the control group ( P < .001). When the dementia group was analyzed by itself, patients with VaD had higher PV levels than the patients with AD ( P < .001). The PV is a biomarker to be used in diagnosis as well as in differentiating between the 2 most common forms of dementia which are AD and VaD. </jats:p> Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? American Journal of Alzheimer's Disease & Other Dementiasr |
doi_str_mv |
10.1177/1533317512467682 |
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SAGE Publications, 2013 |
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2013 |
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SAGE Publications |
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American Journal of Alzheimer's Disease & Other Dementiasr |
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49 |
title_sub |
Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title |
Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_unstemmed |
Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_full |
Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_fullStr |
Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_full_unstemmed |
Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_short |
Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_sort |
plasma viscosity : is a biomarker for the differential diagnosis of alzheimer’s disease and vascular dementia? |
topic |
Psychiatry and Mental health Geriatrics and Gerontology Clinical Psychology General Neuroscience |
url |
http://dx.doi.org/10.1177/1533317512467682 |
publishDate |
2013 |
physical |
62-68 |
description |
<jats:p> In this study, the importance of plasma viscosity (PV) as a biomarker in differential diagnosis of dementia subtypes especially Alzheimer’s disease (AD) and vascular dementia (VaD) was investigated. Our study recruited 45 patients with AD, 35 patients with VaD, and control participants. Individuals with inflammatory disease, infection, heart, liver, renal failure, and with high erythrocyte sedimentation rate and C-reactive protein levels were excluded from the study. The cases underwent comprehensive geriatric assessment. The PV measurements were performed with Brookfield DV-II viscometer. The PV measurements of AD, VaD, and control groups were 1.61 ± 0.08, 1.70 ± 0.06, and 1.48 ± 0.06 mPa S, respectively. The PV levels of the dementia group were significantly higher than the control group ( P < .001). When the dementia group was analyzed by itself, patients with VaD had higher PV levels than the patients with AD ( P < .001). The PV is a biomarker to be used in diagnosis as well as in differentiating between the 2 most common forms of dementia which are AD and VaD. </jats:p> |
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author | Aras, Sevgi, Tek, Ibrahim, Varli, Murat, Yalcin, Ahmet, Cengiz, Ozlem Karaarslan, Atmis, Volkan, Atli, Teslime |
author_facet | Aras, Sevgi, Tek, Ibrahim, Varli, Murat, Yalcin, Ahmet, Cengiz, Ozlem Karaarslan, Atmis, Volkan, Atli, Teslime, Aras, Sevgi, Tek, Ibrahim, Varli, Murat, Yalcin, Ahmet, Cengiz, Ozlem Karaarslan, Atmis, Volkan, Atli, Teslime |
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container_title | American Journal of Alzheimer's Disease & Other Dementiasr |
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description | <jats:p> In this study, the importance of plasma viscosity (PV) as a biomarker in differential diagnosis of dementia subtypes especially Alzheimer’s disease (AD) and vascular dementia (VaD) was investigated. Our study recruited 45 patients with AD, 35 patients with VaD, and control participants. Individuals with inflammatory disease, infection, heart, liver, renal failure, and with high erythrocyte sedimentation rate and C-reactive protein levels were excluded from the study. The cases underwent comprehensive geriatric assessment. The PV measurements were performed with Brookfield DV-II viscometer. The PV measurements of AD, VaD, and control groups were 1.61 ± 0.08, 1.70 ± 0.06, and 1.48 ± 0.06 mPa S, respectively. The PV levels of the dementia group were significantly higher than the control group ( P < .001). When the dementia group was analyzed by itself, patients with VaD had higher PV levels than the patients with AD ( P < .001). The PV is a biomarker to be used in diagnosis as well as in differentiating between the 2 most common forms of dementia which are AD and VaD. </jats:p> |
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spelling | Aras, Sevgi Tek, Ibrahim Varli, Murat Yalcin, Ahmet Cengiz, Ozlem Karaarslan Atmis, Volkan Atli, Teslime 1533-3175 1938-2731 SAGE Publications Psychiatry and Mental health Geriatrics and Gerontology Clinical Psychology General Neuroscience http://dx.doi.org/10.1177/1533317512467682 <jats:p> In this study, the importance of plasma viscosity (PV) as a biomarker in differential diagnosis of dementia subtypes especially Alzheimer’s disease (AD) and vascular dementia (VaD) was investigated. Our study recruited 45 patients with AD, 35 patients with VaD, and control participants. Individuals with inflammatory disease, infection, heart, liver, renal failure, and with high erythrocyte sedimentation rate and C-reactive protein levels were excluded from the study. The cases underwent comprehensive geriatric assessment. The PV measurements were performed with Brookfield DV-II viscometer. The PV measurements of AD, VaD, and control groups were 1.61 ± 0.08, 1.70 ± 0.06, and 1.48 ± 0.06 mPa S, respectively. The PV levels of the dementia group were significantly higher than the control group ( P < .001). When the dementia group was analyzed by itself, patients with VaD had higher PV levels than the patients with AD ( P < .001). The PV is a biomarker to be used in diagnosis as well as in differentiating between the 2 most common forms of dementia which are AD and VaD. </jats:p> Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? American Journal of Alzheimer's Disease & Other Dementiasr |
spellingShingle | Aras, Sevgi, Tek, Ibrahim, Varli, Murat, Yalcin, Ahmet, Cengiz, Ozlem Karaarslan, Atmis, Volkan, Atli, Teslime, American Journal of Alzheimer's Disease & Other Dementiasr, Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia?, Psychiatry and Mental health, Geriatrics and Gerontology, Clinical Psychology, General Neuroscience |
title | Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_full | Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_fullStr | Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_full_unstemmed | Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_short | Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_sort | plasma viscosity : is a biomarker for the differential diagnosis of alzheimer’s disease and vascular dementia? |
title_sub | Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
title_unstemmed | Plasma Viscosity : Is a Biomarker for the Differential Diagnosis of Alzheimer’s Disease and Vascular Dementia? |
topic | Psychiatry and Mental health, Geriatrics and Gerontology, Clinical Psychology, General Neuroscience |
url | http://dx.doi.org/10.1177/1533317512467682 |