author_facet Khan, A. U.
Khan, A. U.
author Khan, A. U.
spellingShingle Khan, A. U.
Journal of International Medical Research
Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
Biochemistry (medical)
Cell Biology
Biochemistry
General Medicine
author_sort khan, a. u.
spelling Khan, A. U. 0300-0605 1473-2300 SAGE Publications Biochemistry (medical) Cell Biology Biochemistry General Medicine http://dx.doi.org/10.1177/030006058701500302 <jats:p> Nineteen elderly hypertensive patients already being treated with a diuretic and, where necessary, another anti-hypertensive agent, were studied in a double-blind, randomized, crossover comparison of conventional propranolol, 40 mg three times daily, with a long-acting propranolol formulation, 160 mg once daily, as a second line agent. Patients were assessed before taking the morning's allocated medication. This was done as near as possible to 24 h after the last dose of once daily propranolol and as near as possible to 15 h after the last dose of three times daily conventional propranolol. Assessment was carried out at the time of randomization and after 4 weeks' treatment with both propranolol formulations. Heart rate and blood pressures were measured in the supine and standing positions and after exercise. Both propranolol formulations were effective as second line agents in these elderly patients and both were well tolerated. Patient compliance on both propranolol formulations was very good although the long-acting formulation may be of value in improving this still further. </jats:p> Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients Journal of International Medical Research
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title Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
title_unstemmed Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
title_full Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
title_fullStr Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
title_full_unstemmed Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
title_short Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
title_sort comparison of a long-acting form of propranolol and conventional propranolol in the treatment of hypertension in elderly patients
topic Biochemistry (medical)
Cell Biology
Biochemistry
General Medicine
url http://dx.doi.org/10.1177/030006058701500302
publishDate 1987
physical 128-133
description <jats:p> Nineteen elderly hypertensive patients already being treated with a diuretic and, where necessary, another anti-hypertensive agent, were studied in a double-blind, randomized, crossover comparison of conventional propranolol, 40 mg three times daily, with a long-acting propranolol formulation, 160 mg once daily, as a second line agent. Patients were assessed before taking the morning's allocated medication. This was done as near as possible to 24 h after the last dose of once daily propranolol and as near as possible to 15 h after the last dose of three times daily conventional propranolol. Assessment was carried out at the time of randomization and after 4 weeks' treatment with both propranolol formulations. Heart rate and blood pressures were measured in the supine and standing positions and after exercise. Both propranolol formulations were effective as second line agents in these elderly patients and both were well tolerated. Patient compliance on both propranolol formulations was very good although the long-acting formulation may be of value in improving this still further. </jats:p>
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author Khan, A. U.
author_facet Khan, A. U., Khan, A. U.
author_sort khan, a. u.
container_issue 3
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container_title Journal of International Medical Research
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description <jats:p> Nineteen elderly hypertensive patients already being treated with a diuretic and, where necessary, another anti-hypertensive agent, were studied in a double-blind, randomized, crossover comparison of conventional propranolol, 40 mg three times daily, with a long-acting propranolol formulation, 160 mg once daily, as a second line agent. Patients were assessed before taking the morning's allocated medication. This was done as near as possible to 24 h after the last dose of once daily propranolol and as near as possible to 15 h after the last dose of three times daily conventional propranolol. Assessment was carried out at the time of randomization and after 4 weeks' treatment with both propranolol formulations. Heart rate and blood pressures were measured in the supine and standing positions and after exercise. Both propranolol formulations were effective as second line agents in these elderly patients and both were well tolerated. Patient compliance on both propranolol formulations was very good although the long-acting formulation may be of value in improving this still further. </jats:p>
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spelling Khan, A. U. 0300-0605 1473-2300 SAGE Publications Biochemistry (medical) Cell Biology Biochemistry General Medicine http://dx.doi.org/10.1177/030006058701500302 <jats:p> Nineteen elderly hypertensive patients already being treated with a diuretic and, where necessary, another anti-hypertensive agent, were studied in a double-blind, randomized, crossover comparison of conventional propranolol, 40 mg three times daily, with a long-acting propranolol formulation, 160 mg once daily, as a second line agent. Patients were assessed before taking the morning's allocated medication. This was done as near as possible to 24 h after the last dose of once daily propranolol and as near as possible to 15 h after the last dose of three times daily conventional propranolol. Assessment was carried out at the time of randomization and after 4 weeks' treatment with both propranolol formulations. Heart rate and blood pressures were measured in the supine and standing positions and after exercise. Both propranolol formulations were effective as second line agents in these elderly patients and both were well tolerated. Patient compliance on both propranolol formulations was very good although the long-acting formulation may be of value in improving this still further. </jats:p> Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients Journal of International Medical Research
spellingShingle Khan, A. U., Journal of International Medical Research, Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients, Biochemistry (medical), Cell Biology, Biochemistry, General Medicine
title Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
title_full Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
title_fullStr Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
title_full_unstemmed Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
title_short Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
title_sort comparison of a long-acting form of propranolol and conventional propranolol in the treatment of hypertension in elderly patients
title_unstemmed Comparison of a Long-Acting Form of Propranolol and Conventional Propranolol in the Treatment of Hypertension in Elderly Patients
topic Biochemistry (medical), Cell Biology, Biochemistry, General Medicine
url http://dx.doi.org/10.1177/030006058701500302