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Extranodal NK/T-cell lymphoma in adolescents: imaging findings of a consecutive 7-year case series

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Bibliographische Detailangaben
Zeitschriftentitel: Journal of International Medical Research
Personen und Körperschaften: Guan, Pujun, Chen, Zihang, Chu, Lei, Zhen, Li, Zhang, Li, Pan, Ling, Liu, Weiping, Liu, Rongbo
In: Journal of International Medical Research, 47, 2019, 3, S. 1210-1220
Format: E-Article
Sprache: Englisch
veröffentlicht:
SAGE Publications
Schlagwörter:
Biochemistry (medical)
Cell Biology
Biochemistry
General Medicine
Details
Zusammenfassung: <jats:sec><jats:title>Objectives</jats:title><jats:p> Extranodal NK/T-cell lymphoma is reportedly a rare but emerging type of lymphoma in adolescents. The present study was performed to specify its imaging characteristics. </jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p> Our hospital’s picture archiving and communication systems were searched from January 2009 to December 2016. We identified 13 patients aged &lt;18 years with pathologically confirmed extranodal NK/T-cell lymphoma in the head and neck region. The computed tomography and magnetic resonance images were reviewed to summarize the imaging characteristics of extranodal NK/T-cell lymphoma in adolescents. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> The mean age at onset was 15.2 ± 1.46 years (range, 12–17 years) with a male:female ratio of 1.17:1.00. Most of the patients (n = 10) displayed nasal cavity and/or paranasal involvement. The tumor was homogeneous in both computed tomography and magnetic resonance images and showed slight enhancement. No calcification or liquefactive necrosis was observed. Adjacent structures were usually involved. </jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p> Suggestive imaging characteristics could acquaint specialists with extranodal NK/T-cell lymphoma in adolescents, facilitating improved early recognition of the diagnosis and helping to improve the patient’s outcome. </jats:p></jats:sec>
Umfang: 1210-1220
ISSN: 0300-0605
1473-2300
DOI: 10.1177/0300060518822406