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The Amount of Weight Loss Six Months after Bariatric Surgery: It Makes a Difference

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Bibliographische Detailangaben
Zeitschriftentitel: Obesity Facts
Personen und Körperschaften: Nedeljkovic-Arsenovic, Olga, Banovic, Marko, Radenkovic, Dejan, Rancic, Nemanja, Polovina, Snezana, Micic, Dragan, Nedeljkovic, Ivana
In: Obesity Facts, 12, 2019, 3, S. 281-290
Format: E-Article
Sprache: Englisch
veröffentlicht:
S. Karger AG
Schlagwörter:
Physiology (medical)
Health (social science)
Details
Zusammenfassung: <jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; Bariatric surgery, especially Roux-en-Y gastric bypass (RYGB), has become the most frequently used therapy for morbid obesity. &lt;b&gt;&lt;i&gt;Objectives:&lt;/i&gt;&lt;/b&gt; The aim of this study was to examine the effects of surgically induced weight loss on cardiopulmonary function 6 months after the procedure, as well as the effect of such an intervention on well-known risk factors for cardiovascular diseases. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; This is a cross-sectional study on 66 morbidly obese patients (BMI ≥40 or ≥35 kg/m&lt;sup&gt;2&lt;/sup&gt; with present comorbidities), comparing their cardiopulmonary function prior to and 6 months after RYGB surgery. &lt;b&gt;&lt;i&gt;Results:&lt;/i&gt;&lt;/b&gt; The substantial amount of weight loss (29.80 ± 13.27 kg) after RYGB surgery was associated with significant reduction of comorbidities, especially diabetes and sedentary lifestyle (&lt;i&gt;p&lt;/i&gt; = 0.005 and &lt;i&gt;p&lt;/i&gt; = 0.002, respectively). Regarding functional capacity, there was significant increase in peak oxygen uptake (VO&lt;sub&gt;2&lt;/sub&gt; peak, &lt;i&gt;p&lt;/i&gt; = 0.003), duration of exercise testing, metabolic equivalents (exercise time and METs, &lt;i&gt;p&lt;/i&gt; &amp;#x3c; 0.001), and in peak O&lt;sub&gt;2&lt;/sub&gt; pulse. These findings were particularly pronounced in a group of patients who had lost more than 18% of initial weight. &lt;b&gt;&lt;i&gt;Conclusions:&lt;/i&gt;&lt;/b&gt; Reduction of body weight after RYGB surgery is associated with significantly improved cardiorespiratory function 6 months after surgery, especially in patients who lost more than 18% of their initial body weight. In addition, substantial decreases in body weight were also associated with a reduction of cardiovascular risk factors such as diabetes, smoking, hypertriglyceridemia, and sedentary lifestyle.</jats:p>
Umfang: 281-290
ISSN: 1662-4025
1662-4033
DOI: 10.1159/000499387