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Zusammenfassung: <jats:title>Abstract</jats:title> <jats:p>Cancer is a disease of the genome. High-throughput genome analysis tools now enable the detection of somatic alterations in cancer cells including point mutations, copy number alterations, translocations, and infections. Our approaches include next-generation sequencing of cancer genomes, exomes, and transcriptomes as well as single nucleotide polymorphisms (SNP) array analysis of copy number.</jats:p> <jats:p>As part of “The Cancer Genome Atlas” or TCGA project of the National Institutes of Health, which aims to characterize the genomes of 10,000 human cancers, we are performing genomic analysis of lung carcinomas. In this presentation, I will discuss analysis of the genomes of squamous cell lung carcinomas. New results regarding mutations, genomic structure, and classification will be presented.</jats:p>
Umfang: IA7-IA7
ISSN: 1078-0432
1557-3265
DOI: 10.1158/1078-0432.12aacriaslc-ia7