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Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report
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| Zeitschriftentitel: | Journal of Ophthalmology |
|---|---|
| Personen und Körperschaften: | , |
| In: | Journal of Ophthalmology, 2010, 2010, S. 1-3 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Hindawi Limited
|
| Schlagwörter: |
| author_facet |
De Benedetti, Giacomo Brancaccio, Andrea De Benedetti, Giacomo Brancaccio, Andrea |
|---|---|
| author |
De Benedetti, Giacomo Brancaccio, Andrea |
| spellingShingle |
De Benedetti, Giacomo Brancaccio, Andrea Journal of Ophthalmology Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report Ophthalmology |
| author_sort |
de benedetti, giacomo |
| spelling |
De Benedetti, Giacomo Brancaccio, Andrea 2090-004X 2090-0058 Hindawi Limited Ophthalmology http://dx.doi.org/10.1155/2010/296034 <jats:p><jats:italic>Purpose</jats:italic>. To report one case of corneal antibiotic deposition after ciprofloxacin administration in Laser Assisted Subepithelial Keratomileusis (LASEK).<jats:italic>Methods</jats:italic>. One case of post-LASEK treatment resulted in corneal precipitates and poor wound healing. Debris was analyzed with dark field microscopy and placed on a blood-agar plate seeded with a susceptible stain of<jats:italic>Staphylococcus aureus</jats:italic>(ATCC 29213).<jats:italic>Results</jats:italic>. The alterations resolved with discontinuation of ciprofloxacin treatment, although some residual deposits persisted subepithelially for 6 months. Analysis of precipitates revealed polydisperse crystalline needles of 183 m average length ( m) and the excised precipitate demonstrated a zone of inhibition.<jats:italic>Conclusions</jats:italic>. Fluoroquinolone antibiotic drops have been used extensively in postsurgical treatment of refractive surgery. Corneal precipitates have been previously reported in the literature, but up to now nothing has been documented after LASEK. Polypharmacy during refractive surgery may impair epithelialisation, and clinical management should reduce toxic environment and promote ocular surface stability when performing surface ablations.</jats:p> Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report Journal of Ophthalmology |
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| title |
Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| title_unstemmed |
Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| title_full |
Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| title_fullStr |
Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| title_full_unstemmed |
Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| title_short |
Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| title_sort |
corneal deposit of ciprofloxacin after laser assisted subepithelial keratomileusis procedure: a case report |
| topic |
Ophthalmology |
| url |
http://dx.doi.org/10.1155/2010/296034 |
| publishDate |
2010 |
| physical |
1-3 |
| description |
<jats:p><jats:italic>Purpose</jats:italic>. To report one case of corneal antibiotic deposition after ciprofloxacin administration in Laser Assisted Subepithelial Keratomileusis (LASEK).<jats:italic>Methods</jats:italic>. One case of post-LASEK treatment resulted in corneal precipitates and poor wound healing. Debris was analyzed with dark field microscopy and placed on a blood-agar plate seeded with a susceptible stain of<jats:italic>Staphylococcus aureus</jats:italic>(ATCC 29213).<jats:italic>Results</jats:italic>. The alterations resolved with discontinuation of ciprofloxacin treatment, although some residual deposits persisted subepithelially for 6 months. Analysis of precipitates revealed polydisperse crystalline needles of 183 m average length ( m) and the excised precipitate demonstrated a zone of inhibition.<jats:italic>Conclusions</jats:italic>. Fluoroquinolone antibiotic drops have been used extensively in postsurgical treatment of refractive surgery. Corneal precipitates have been previously reported in the literature, but up to now nothing has been documented after LASEK. Polypharmacy during refractive surgery may impair epithelialisation, and clinical management should reduce toxic environment and promote ocular surface stability when performing surface ablations.</jats:p> |
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| author | De Benedetti, Giacomo, Brancaccio, Andrea |
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| author_sort | de benedetti, giacomo |
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| description | <jats:p><jats:italic>Purpose</jats:italic>. To report one case of corneal antibiotic deposition after ciprofloxacin administration in Laser Assisted Subepithelial Keratomileusis (LASEK).<jats:italic>Methods</jats:italic>. One case of post-LASEK treatment resulted in corneal precipitates and poor wound healing. Debris was analyzed with dark field microscopy and placed on a blood-agar plate seeded with a susceptible stain of<jats:italic>Staphylococcus aureus</jats:italic>(ATCC 29213).<jats:italic>Results</jats:italic>. The alterations resolved with discontinuation of ciprofloxacin treatment, although some residual deposits persisted subepithelially for 6 months. Analysis of precipitates revealed polydisperse crystalline needles of 183 m average length ( m) and the excised precipitate demonstrated a zone of inhibition.<jats:italic>Conclusions</jats:italic>. Fluoroquinolone antibiotic drops have been used extensively in postsurgical treatment of refractive surgery. Corneal precipitates have been previously reported in the literature, but up to now nothing has been documented after LASEK. Polypharmacy during refractive surgery may impair epithelialisation, and clinical management should reduce toxic environment and promote ocular surface stability when performing surface ablations.</jats:p> |
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| spelling | De Benedetti, Giacomo Brancaccio, Andrea 2090-004X 2090-0058 Hindawi Limited Ophthalmology http://dx.doi.org/10.1155/2010/296034 <jats:p><jats:italic>Purpose</jats:italic>. To report one case of corneal antibiotic deposition after ciprofloxacin administration in Laser Assisted Subepithelial Keratomileusis (LASEK).<jats:italic>Methods</jats:italic>. One case of post-LASEK treatment resulted in corneal precipitates and poor wound healing. Debris was analyzed with dark field microscopy and placed on a blood-agar plate seeded with a susceptible stain of<jats:italic>Staphylococcus aureus</jats:italic>(ATCC 29213).<jats:italic>Results</jats:italic>. The alterations resolved with discontinuation of ciprofloxacin treatment, although some residual deposits persisted subepithelially for 6 months. Analysis of precipitates revealed polydisperse crystalline needles of 183 m average length ( m) and the excised precipitate demonstrated a zone of inhibition.<jats:italic>Conclusions</jats:italic>. Fluoroquinolone antibiotic drops have been used extensively in postsurgical treatment of refractive surgery. Corneal precipitates have been previously reported in the literature, but up to now nothing has been documented after LASEK. Polypharmacy during refractive surgery may impair epithelialisation, and clinical management should reduce toxic environment and promote ocular surface stability when performing surface ablations.</jats:p> Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report Journal of Ophthalmology |
| spellingShingle | De Benedetti, Giacomo, Brancaccio, Andrea, Journal of Ophthalmology, Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report, Ophthalmology |
| title | Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| title_full | Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| title_fullStr | Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| title_full_unstemmed | Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| title_short | Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| title_sort | corneal deposit of ciprofloxacin after laser assisted subepithelial keratomileusis procedure: a case report |
| title_unstemmed | Corneal Deposit of Ciprofloxacin after Laser Assisted Subepithelial Keratomileusis Procedure: A Case Report |
| topic | Ophthalmology |
| url | http://dx.doi.org/10.1155/2010/296034 |