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Kelly, Brent
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Malone, C. Helen
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author Boisen, Julie
Malone, C. Helen
Kelly, Brent
Wagner, Richard F.
spellingShingle Boisen, Julie
Malone, C. Helen
Kelly, Brent
Wagner, Richard F.
Case Reports in Dermatological Medicine
Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
Dermatology
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spelling Boisen, Julie Malone, C. Helen Kelly, Brent Wagner, Richard F. 2090-6463 2090-6471 Hindawi Limited Dermatology http://dx.doi.org/10.1155/2016/9067428 <jats:p>Cutaneous squamous cell carcinoma of the ear represents a high-risk tumor location with an increased risk of metastasis and local tissue invasion. However, it is uncommon for these cancers to invade through nearby cartilage. Cartilage invasion is facilitated by matrix metalloproteases, specifically collagenase 3. We present the unusual case of a 76-year-old man with an auricular squamous cell carcinoma that exhibited full-thickness perforation of the scapha cartilage. Permanent sections through the eroded cartilage confirmed tumor invasion extending to the posterior ear skin.</jats:p> Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage Case Reports in Dermatological Medicine
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title Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_unstemmed Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_full Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_fullStr Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_full_unstemmed Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_short Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_sort cutaneous squamous cell carcinoma with invasion through ear cartilage
topic Dermatology
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description <jats:p>Cutaneous squamous cell carcinoma of the ear represents a high-risk tumor location with an increased risk of metastasis and local tissue invasion. However, it is uncommon for these cancers to invade through nearby cartilage. Cartilage invasion is facilitated by matrix metalloproteases, specifically collagenase 3. We present the unusual case of a 76-year-old man with an auricular squamous cell carcinoma that exhibited full-thickness perforation of the scapha cartilage. Permanent sections through the eroded cartilage confirmed tumor invasion extending to the posterior ear skin.</jats:p>
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spelling Boisen, Julie Malone, C. Helen Kelly, Brent Wagner, Richard F. 2090-6463 2090-6471 Hindawi Limited Dermatology http://dx.doi.org/10.1155/2016/9067428 <jats:p>Cutaneous squamous cell carcinoma of the ear represents a high-risk tumor location with an increased risk of metastasis and local tissue invasion. However, it is uncommon for these cancers to invade through nearby cartilage. Cartilage invasion is facilitated by matrix metalloproteases, specifically collagenase 3. We present the unusual case of a 76-year-old man with an auricular squamous cell carcinoma that exhibited full-thickness perforation of the scapha cartilage. Permanent sections through the eroded cartilage confirmed tumor invasion extending to the posterior ear skin.</jats:p> Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage Case Reports in Dermatological Medicine
spellingShingle Boisen, Julie, Malone, C. Helen, Kelly, Brent, Wagner, Richard F., Case Reports in Dermatological Medicine, Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage, Dermatology
title Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_full Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_fullStr Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_full_unstemmed Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_short Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_sort cutaneous squamous cell carcinoma with invasion through ear cartilage
title_unstemmed Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
topic Dermatology
url http://dx.doi.org/10.1155/2016/9067428