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Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications
Gespeichert in:
Zeitschriftentitel: | Stem Cells International |
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Personen und Körperschaften: | , |
In: | Stem Cells International, 2016, 2016, S. 1-9 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
Hindawi Limited
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Schlagwörter: |
Zusammenfassung: | <jats:p>Aging, chronic inflammation, and environmental insults play an important role in a number of disease processes through alterations of the epigenome. In this review we explore how age-related changes in the epigenetic landscape can affect heterogeneity within the haematopoietic stem cell (HSC) compartment and the deriving clinical implications.</jats:p> |
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Umfang: | 1-9 |
ISSN: |
1687-966X
1687-9678 |
DOI: | 10.1155/2016/5797521 |