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Resistance to Infection With Intracellular Parasites. Identification of a Candidate Gene
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| Zeitschriftentitel: | Physiology |
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| Personen und Körperschaften: | , |
| In: | Physiology, 9, 1994, 4, S. 178-183 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Physiological Society
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| Schlagwörter: |
| Zusammenfassung: | <jats:p> In the mouse, natural resistance to infection with unrelated intracellular parasites is controlled by the Bcg locus. With an positional cloning approach, a candidate gene for Bcg has been isolated. This gene encodes for a novel macrophage-specific transport protein, Nramp, which is altered in innately susceptible animals. </jats:p> |
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| Umfang: | 178-183 |
| ISSN: |
1548-9213
1548-9221 |
| DOI: | 10.1152/physiologyonline.1994.9.4.178 |