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In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis
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| Zeitschriftentitel: | Chemical Science |
|---|---|
| Personen und Körperschaften: | , , , , , , |
| In: | Chemical Science, 6, 2015, 8, S. 5076-5085 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Royal Society of Chemistry (RSC)
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| Schlagwörter: |
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Sucipto, H. Sahner, J. H. Prusov, E. Wenzel, S. C. Hartmann, R. W. Koehnke, J. Müller, R. Sucipto, H. Sahner, J. H. Prusov, E. Wenzel, S. C. Hartmann, R. W. Koehnke, J. Müller, R. |
|---|---|
| author |
Sucipto, H. Sahner, J. H. Prusov, E. Wenzel, S. C. Hartmann, R. W. Koehnke, J. Müller, R. |
| spellingShingle |
Sucipto, H. Sahner, J. H. Prusov, E. Wenzel, S. C. Hartmann, R. W. Koehnke, J. Müller, R. Chemical Science In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis General Chemistry |
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sucipto, h. |
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Sucipto, H. Sahner, J. H. Prusov, E. Wenzel, S. C. Hartmann, R. W. Koehnke, J. Müller, R. 2041-6520 2041-6539 Royal Society of Chemistry (RSC) General Chemistry http://dx.doi.org/10.1039/c5sc01013f <p>α-Pyrone rings exist in many polyketide synthase (PKS) derived natural products. We report the first <italic>in vitro</italic> reconstitution of α-pyrone ring formation by a type I PKS using chemically synthesized substrates.</p> In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis Chemical Science |
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| title |
In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_unstemmed |
In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_full |
In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_fullStr |
In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_full_unstemmed |
In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_short |
In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_sort |
in vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| topic |
General Chemistry |
| url |
http://dx.doi.org/10.1039/c5sc01013f |
| publishDate |
2015 |
| physical |
5076-5085 |
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<p>α-Pyrone rings exist in many polyketide synthase (PKS) derived natural products. We report the first <italic>in vitro</italic> reconstitution of α-pyrone ring formation by a type I PKS using chemically synthesized substrates.</p> |
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| author | Sucipto, H., Sahner, J. H., Prusov, E., Wenzel, S. C., Hartmann, R. W., Koehnke, J., Müller, R. |
| author_facet | Sucipto, H., Sahner, J. H., Prusov, E., Wenzel, S. C., Hartmann, R. W., Koehnke, J., Müller, R., Sucipto, H., Sahner, J. H., Prusov, E., Wenzel, S. C., Hartmann, R. W., Koehnke, J., Müller, R. |
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| container_title | Chemical Science |
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| description | <p>α-Pyrone rings exist in many polyketide synthase (PKS) derived natural products. We report the first <italic>in vitro</italic> reconstitution of α-pyrone ring formation by a type I PKS using chemically synthesized substrates.</p> |
| doi_str_mv | 10.1039/c5sc01013f |
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| imprint | Royal Society of Chemistry (RSC), 2015 |
| imprint_str_mv | Royal Society of Chemistry (RSC), 2015 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229 |
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| series | Chemical Science |
| source_id | 49 |
| spelling | Sucipto, H. Sahner, J. H. Prusov, E. Wenzel, S. C. Hartmann, R. W. Koehnke, J. Müller, R. 2041-6520 2041-6539 Royal Society of Chemistry (RSC) General Chemistry http://dx.doi.org/10.1039/c5sc01013f <p>α-Pyrone rings exist in many polyketide synthase (PKS) derived natural products. We report the first <italic>in vitro</italic> reconstitution of α-pyrone ring formation by a type I PKS using chemically synthesized substrates.</p> In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis Chemical Science |
| spellingShingle | Sucipto, H., Sahner, J. H., Prusov, E., Wenzel, S. C., Hartmann, R. W., Koehnke, J., Müller, R., Chemical Science, In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis, General Chemistry |
| title | In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_full | In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_fullStr | In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_full_unstemmed | In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_short | In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_sort | in vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| title_unstemmed | In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis |
| topic | General Chemistry |
| url | http://dx.doi.org/10.1039/c5sc01013f |